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Article

Benchmarking whole exome sequencing in the German network for personalized medicine.
Menzel, M., Martis-Thiele, M., Goldschmid, H., Ott, A., Romanovsky, E., Siemanowski-Hrach, J., Seillier, L., Brüchle, N.O., Maurer, A., Lehmann, K.V., Begemann, M., Elbracht, M., Meyer, R., Dintner, S., Claus, R., Meier-Kolthoff, J.P, Blanc, E., Möbs, M., Joosten, M., Benary, M., Basitta, P., Hölscher, F., Tischler, V., Groß, T., Kutz, O., Prause, R., William, D., Horny, Kai, Goering, W., Sivalingam, S., Borkhardt, A., Blank, C., Junk, S.V., Yasin, L., Moskalev, E.A., Carta, M.G., Ferrazzi, F., Tögel, L., Wolter, S., Adam, E., Matysiak, U., Rosenthal, T., Dönitz, J., Lehmann, U., Schmidt, G., Bartels, S., Hofmann, W., Hirsch, S., Dikow, N., Göbel, K., Banan, R., Hamelmann, S., Fink, A., Ball, M., Neumann, O., Rehker, J., Kloth, M., Murtagh, J., Hartmann, N., Jurmeister, P., Mock, A., Kumbrink, J., Jung, A., Mayr, E.M., Jacob, A., Trautmann, M., Kirmse, S., Falkenberg, K., Ruckert, C., Hirsch, D., Immel, A., Dietmaier, W., Haack, T., Marienfeld, R., Fürstberger, A., Niewöhner, J., Gerstenmaier, U., Eberhardt, T., Greif, P.A., Appenzeller, S., Maurus, K., Doll, J., Jelting, Y., Jonigk, D., Märkl, B., Beule, D., Horst, D., Wulf, A.L., Aust, D., Werner, M., Reuter-Jessen, K., Ströbel, P., Auber, B., Sahm, F., Merkelbach-Bruse, S., Siebolts, U., Roth, W., Lassmann, S., Klauschen, F., Gaisa, N.T., Weichert, W., Evert, M., Armeanu-Ebinger, S., Ossowski, S., Schroeder, C., Schaaf, C.P., Malek, N., Schirmacher, P., Kazdal, D., Pfarr, N., Budczies, J. and Stenzinger, A.
European Journal of Cancer 211 : 114306. November 2024

A prospective observational study of real-world treatment and outcome in secondary CNS lymphoma.
Habringer, S., Demel, U.M., Fietz, A.K., Lammer, F., Schroers, R., Hofer, S., Bairey, O., Braess, J., Meier-Stiegen, A.S., Stuhlmann, R., Schmidt-Hieber, M., Hoffmann, J., Zinngrebe, B., Kaiser, U., Reimer, P., Möhle, R., Fix, P., Höffkes, H.G., Langenkamp, U., Büschenfelde, C.M.Z., Hopfer, O., Stoltefuß, A., La Rosée, P., Blasberg, H., Jordan, K., Kaun, S., Meurer, A., Unteroberdörster, M., von Brünneck, A.C., Capper, D., Heppner, F.L., Chapuy, B., Janz, M., Schwartz, S., Konietschke, F., Vajkoczy, P., Korfel, A. and Keller, U.
European Journal of Cancer 196 : 113436. January 2024

TTF-1 status in early-stage lung adenocarcinoma is an independent predictor of relapse and survival superior to tumor grading.
Schallenberg, S., Dernbach, G., Dragomir, M.P., Schlachtenberger, G., Boschung, K., Friedrich, C., Standvoss, K., Ruff, L., Anders, P., Grohé, C., Randerath, W., Merkelbach-Bruse, S., Quaas, A., Heldwein, M., Keilholz, U., Hekmat, J.K., Rückert, C., Büttner, R., Horst, D., Klauschen, F. and Frost, N.
European Journal of Cancer 197 : 113474. January 2024

Tumour mutational burden and survival with molecularly matched therapy.
de Bortoli, T., Benary, M., Horak, P., Lamping, M., Stintzing, S., Tinhofer, I., Leyvraz, S., Schäfer, R., Klauschen, F., Keller, U., Stenzinger, A., Fröhling, S., Kurzrock, R., Keilholz, U., Rieke, D.T. and Jelas, I.
European Journal of Cancer 190 : 112925. September 2023

Treatment with ribociclib shows favourable immunomodulatory effects in patients with hormone receptor-positive breast cancer-findings from the RIBECCA trial.
Peuker, C.A., Yaghobramzi, S., Grunert, C., Keilholz, L, Gjerga, E., Hennig, S., Schaper, S., Na, I.K., Keller, U., Brucker, S., Decker, T., Fasching, P., Fehm, T., Janni, W., Kümmel, S., Schneeweiss, A., Schuler, M., Lüftner, D. and Busse, A.
European Journal of Cancer 162 : 45-55. February 2022

Support of a molecular tumour board by an evidence-based decision management system for precision oncology.
Lamping, M., Benary, M., Leyvraz, S., Messerschmidt, C., Blanc, E., Kessler, T., Schütte, M., Lenze, D., Jöhrens, K., Burock, S., Klinghammer, K., Ochsenreither, S., Sers, C., Schäfer, R., Tinhofer, I., Beule, D., Klauschen, F., Yaspo, M.L., Keilholz, U. and Rieke, D.T.
European Journal of Cancer 127 : 41-51. March 2020

Prognostic impact of immune response in resectable colorectal liver metastases treated by surgery alone or surgery with perioperative FOLFOX in the randomised EORTC study 40983.
Tanis, E., Julie, C., Emile, J.F., Mauer, M., Nordlinger, B., Aust, D., Roth, A., Lutz, M.P., Gruenberger, T., Wrba, F., Sorbye, H., Bechstein, W., Schlag, P., Fisseler, A. and Ruers, T.
European Journal of Cancer 51 (17): 2708-2717. November 2015

Influence of comorbidity, age and performance status on treatment efficacy and safety of cetuximab plus irinotecan in irinotecan-refractory elderly patients with metastatic colorectal cancer.
Jehn, C.F., Böning, L., Kröning, H., Pezzutto, A. and Lüftner, D.
European Journal of Cancer 50 (7): 1269-1275. May 2014

Adult weight change and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition.
Aleksandrova, K., Pischon, T., Buijsse, B., May, A.M., Peeters, P.H., Bueno-de-Mesquita, H.B., Jenab, M., Fedirko, V., Dahm, C.C., Siersema, P.D., Freisling, H., Ferrari, P., Overvad, K., Tjønneland, A., Trichopoulou, A., Lagiou, P., Naska, A., Pala, V., Mattiello, A., Ohlsson, B., Jirström, K., Key, T.J., Khaw, K.T., Riboli, E. and Boeing, H.
European Journal of Cancer 49 (16): 3526-3536. November 2013

Comparative evaluation of the biological properties of reducible and acid-sensitive folate prodrugs of a highly potent doxorubicin derivative.
Abu Ajaj, K., El-Abadla, N., Welker, P., Azab, S., Zeisig, R., Fichtner, I. and Kratz, F.
European Journal of Cancer 48 (13): 2054-2065. September 2012

The impact of short-term psycho-oncological interventions on the psychological outcome of cancer patients of a surgical-oncology department - A randomised controlled study.
Goerling, U., Foerg, A., Sander, S., Schramm, N. and Schlag, P.M.
European Journal of Cancer 47 (13): 2009-2014. September 2011

Best supportive care (BSC) versus oxaliplatin, folinic acid and 5-fluorouracil (OFF) plus BSC in patients for second-line advanced pancreatic cancer: A phase III-study from the German CONKO-study group.
Pelzer, U., Schwaner, I., Stieler, J., Adler, M., Seraphin, J., Doerken, B., Riess, H. and Oettle, H.
European Journal of Cancer 47 (11): 1676-1681. July 2011

In vivo models for endocrine-dependent breast carcinomas: special considerations of clinical relevance.
Fichtner, I., Becker, M., Zeisig, R. and Sommer, A.
European Journal of Cancer 40 (6): 845-851. April 2004

Detection of cell-free nucleic acids in bronchial lavage fluid supernatants from patients with lung cancer.
Schmidt, B., Carstensen, T., Engel, E., Jandrig, B., Witt, C. and Fleischhacker, M.
European Journal of Cancer 40 (3): 452-460. February 2004

Anticancer drug response and expression of molecular markers in early-passage xenotransplanted colon carcinomas.
Fichtner, I., Slisow, W., Gill, J., Becker, M., Elbe, B., Hillebrand, T. and Bibby, M.
European Journal of Cancer 40 (2): 298-307. January 2004

Outcome analysis of 189 consecutive cancer patients referred to the intensive care unit as emergencies during a 2-year period.
Maschmeyer, G., Bertschat, F.L., Moesta, K.T., Haeusler, E., Held, T.K., Nolte, M., Osterziel, K.J., Papstein, V., Peters, M., Reich, G., Schmutzler, M., Sezer, O., Stula, M., Wauer, H., Woertz, T., Wischnewsky, M. and Hohenberger, P.
European Journal of Cancer 39 : 783-792. 1 April 2003

Antileukaemic activity of treosulfan in xenografted human acute lymphoblastic leukaemias (ALL).
Fichtner, I., Becker, M. and Baumgart, J.
European Journal of Cancer 39 (6): 801-807. April 2003

The EORTC laboratory research division.
Brunner, N., Double, J., Fichtner, I., Gescher, A., Newell, D., Oosterhuis, W. and Price, P.
European Journal of Cancer 38 (4): S14-S18. March 2002

Colorectal cancer - what is standard surgery?
Hohenberger, P.
European Journal of Cancer 37 (S7) : 173-187. 1 January 2001

Refined deletion mapping in sporadic breast cancer at chromosomal region 8p12-p21 and association with clinicopathological parameters.
Seitz, S., Werner, S., Fischer, J., Nothnagel, A., Schlag, P.M. and Scherneck, S.
European Journal of Cancer 36 (12): 1507-1513. 1 August 2000

Brain metastases in breast cancer: prognostic factors and management.
Lentzsch, S., Reichardt, P., Weber, F., Budach, V. and Doerken, B.
European Journal of Cancer 35 : 580-585. 1 April 1999

Reduction of chemotherapy-induced side-effects by parenteral glutamine supplementation in patients with metastatic colorectal cancer.
Decker-Baumann, C., Buhl, K., Frohmueller, S., von Herbay, A., Dueck, M. and Schlag, P.M.
European Journal of Cancer 35 : 202-207. 1 February 1999

Expression and regulation by interferon-gamma of the membrane-bound complement regulators CD46 (MCP), CD55 (DAF) and CD59 in gastrointestinal tumours.
Schmitt, C.A., Schwaeble, W., Wittig, B.M., Meyer Zum Bueschenfelde, K.H. and Dippold, W.G.
European Journal of Cancer 35 : 117-124. 1 January 1999

Immunohistological analysis of E-cadherin, alpha-, beta- and gamma-catenin expression in colorectal cancer: Implications for cell adhesion and signaling.
Ghadimi, B.M., Behrens, J., Hoffmann, I., Haensch, W., Birchmeier, W. and Schlag, P.M.
European Journal of Cancer 35 (1): 60-65. January 1999

Increased autologous blood donation in rectal cancer by recombinant human erythropoietin (rhEPO).
Rau, B., Schlag, P.M., Willeke, F., Herfarth, C., Stephan, P. and Franke, W.
European Journal of Cancer 34 : 992-998. 1 June 1998

Rhabdomyolysis and renal function impairment after isolated limb perfusion-comparison between the effects of perfusion with rhTNFalpha 'Triple-drug' regimen.
Hohenberger, P., Haier, J. and Schlag, P.M.
European Journal of Cancer 33 : 596-601. 1 January 1997

Modulation of 5-fluorouracil with methotrexate and low-dose N- (phosphonacetyl)-L-aspartate in patients with advanced colorectal cancer. results of a phase II study.
Koehne, C.H., Harstrick, A., Hiddemann, W., Schoeffski, P., Wilke, H., Bokemeyer, C., Doerken, B. and Schmoll, H.J.
European Journal of Cancer 33 : 1896-1899. 1 January 1997

Is isolated limb perfusion of metastatic malignant melanoma of the extremity worthwhile?
Koops, H.S., Garbe, C. and Hohenberger, P.
European Journal of Cancer 32A : 1633-1640. 1 September 1996

MDR1 gene expression: evaluation of its use as a molecular marker for prognosis and chemotherapy of bone and soft tissue sarcomas.
Stein, U., Shoemaker, R.H. and Schlag, P.M.
European Journal of Cancer 32 A : 86-92. 1 January 1996

European school of oncology position paper - gene therapy for the medical oncologist.
Blaese, M., Blankenstein, T., Brenner, M., Cohenhaguenauer, O., Gansbacher, B., Sorrentino, B. and Velu, T.
European Journal of Cancer 31A (9): 1531-1537. 1 January 1995

A pilot study of a new therapeutic approach in the treatment of locally advanced stages of rectal cancer - neoadjuvant radiation, chemotherapy and regional hyperthermia.
Riess, H., Loeffel, J., Wust, P., Rau, B., Gremmler, M., Speidel, A. and Schlag, P.M.
European Journal of Cancer 31A : 1356-1360. 1 January 1995

Increasing tumour immunogenicity by genetic modification.
Blankenstein, T.
European Journal of Cancer 30A : 1182-1187. 1 January 1994

Serum erythropoietin levels in patients with solid tumours.
Kettelhack, C., Schoeter, D., Matthias, D. and Schlag, P.M.
European Journal of Cancer 30A : 1289-1291. 1 January 1994

Point mutations in the mdr1 promoter of human osteosarcomas are associated with in vitro responsiveness to multidrug resistance relevated drugs.
Stein, U., Walther, W. and Wunderlich, V.
European Journal of Cancer 30A (10): 1541-1545. 1994

Perfusion of colorectal liver metastases and uptake of fluorouracil assessed by H215O and [18F]uracil positron emission tomography (PET).
Hohenberger, P., Strauss, L.G., Lehner, B., Frohmueller, S., Dimitrakopoulou, A. and Schlag, P.M.
European Journal of Cancer 29A : 1682-1686. 1 January 1993

Properties of two epithelial cell lines derived from HPV-associated cervical and vulvar lesions.
Kiessling, U., Kube, D., Janda, J., Bergmann, S., Johannsmeyer, K.D., Hauff, P., Arnold, W. and Waehlte, H.
European Journal of Cancer 29A : 1746-1753. 1 January 1993

Expression of the mdr1 gene in bone and soft tissue sarcomas of adult patients.
Stein, U., Wunderlich, V., Haensch, W. and Schmidt-Peter, P.
European Journal of Cancer 29A (14): 1979-1981. 1993

Selective oral antimicrobial prophylaxis for the prevention of infection in acute leukaemia-ciprofloxacin versus co-trimoxazole plus colistin.
Donnelly, J.P., Maschmeyer, G. and Daenen, S.
European Journal of Cancer 28A : 873-878. 1 January 1992

Review

Paediatric Strategy Forum for medicinal product development of DNA damage response pathway inhibitors in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
Pearson, A.D.J., Federico, S., Gatz, S.A., Ortiz, M., Lesa, G., Scobie, N., Gounaris, I., Weiner, S.L., Weigel, B., Unger, T.J., Stewart, E., Smith, M., Slotkin, E.K., Reaman, G., Pappo, A., Nysom, K., Norga, K., McDonough, J., Marshall, L.V., Ludwinski, D., Ligas, F., Karres, D., Kool, M., Horner, T.J., Henssen, A., Heenen, D., Hawkins, D.S., Gore, L., Bender, J.G., Galluzzo, S., Fox, E., de Rojas, T., Davies, B.R., Chakrabarti, J., Carmichael, J., Bradford, D., Blanc, P., Bernardi, R., Benchetrit, S., Akindele, K. and Vassal, G.
European Journal of Cancer 190 : 112950. September 2023

Target actionability review to evaluate CDK4/6 as a therapeutic target in paediatric solid and brain tumours.
Schubert, N.A., Chen, C.Y., Rodríguez, A., Koster, J., Dowless, M., Pfister, S.M., Shields, D.J., Stancato, L.F., Vassal, G., Caron, H.N., van den Boogaard, M.L., Henssen, A.G. and Molenaar, J.J.
European Journal of Cancer 170 : 196-208. July 2022

Accelerating drug development for neuroblastoma: summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma.
Moreno, L., Barone, G., DuBois, S.G., Molenaar, J., Fischer, M., Schulte, J., Eggert, A., Schleiermacher, G., Speleman, F., Chesler, L., Geoerger, B., Hogarty, M.D., Irwin, M.S., Bird, N., Blanchard, G.B., Buckland, S., Caron, H., Davis, S., De Wilde, B., Deubzer, H.E., Dolman, E., Eilers, M., George, R.E., George, S., Jaroslav, Š., Maris, J.M., Marshall, L., Merchant, M., Mortimer, P., Owens, C., Philpott, A., Poon, E., Shay, J.W., Tonelli, R., Valteau-Couanet, D., Vassal, G., Park, J.R. and Pearson, A.D.J.
European Journal of Cancer 136 : 52-68. September 2020

Sentinel node biopsy in gastrointestinal-tract cancer.
Schlag, P.M., Bembenek, A. and Schulze, T.
European Journal of Cancer 40 (14): 2022-2032. September 2004

Chemotherapy in alveolar soft part sarcomas: What do we know?
Reichardt, P., Lindner, T., Pink, D., Thuss-Patience, P.C., Kretzschmar, A. and Doerken, B.
European Journal of Cancer 39 (11): 1511-1516. 1 July 2003

Palliative endoscopic therapy of rectal carcinoma.
Dohmoto, M., Huenerbein, M. and Schlag, P.M.
European Journal of Cancer 32 (1): 25-29. 1 January 1996

Editorial

Soft tissue sarcoma of high grade - a primary systemic disease?
Hohenberger, P.
European Journal of Cancer 36 : 688-690. 1 April 2000

Immune ageing and cancer.
Hartwig, M.
European Journal of Cancer 28A : 1939-1940. 1 January 1992