Article

Brain atrophy staging in spinocerebellar ataxia type 3 for clinical prognosis and trial enrichment.
Baumeister, Hannah, Wegner, Philipp, Ferreira, Mónica, Schaprian, Tamara, França, Marcondes C., Rezende, Thiago Junqueira Ribeiro, Muro Martinez, Alberto Rolim, Jiang, Hong, Chen, Zhao, Weihua, Liao, Grobe-Einsler, Marcus, Koyak, Berkan, Önder, Demet, van de Warrenburg, Bart, van Gaalen, Judith, Durr, Alexandra, Coarelli, Giulia, Synofzik, Matthis, Schöls, Ludger, Giunti, Paola, Garcia-Moreno, Hector, Öz, Gülin, Joers, James, Timmann, Dagmar, Thieme, Andreas G., Jacobi, Heike, de Vries, Jeroen, Barker, Peter, Onyike, Chiadikaobi, Ratai, Eva-Maria, Schmahmann, Jeremy D., Reetz, Kathrin, Infante, Jon, Huebener-Schmid, Jeannette, Kuegler, David, Klockgether, Thomas, Berron, David and Faber, Jennifer
EBioMedicine 123 : 106090. January 2026

Metabolic inflammation, brain age and cognitive functioning in short- and long-term clinical weight loss trials.
Maurer, Lukas, Kozarzewski, Leonard, Haberbosch, Linus, Flöel, Agnes, Haynes, John-Dylan, Spranger, Joachim ORCID: https://orcid.org/0000-0002-8900-4467, Mai, Knut and Weygandt, Martin ORCID: https://orcid.org/0000-0001-9962-4582
EBioMedicine 123 : 106064. January 2026

HLA-A∗03:01 as predictive genetic biomarker for glatiramer acetate treatment response in multiple sclerosis: a retrospective cohort analysis.
Zhang, Brian C., Schneider-Hohendorf, Tilman, Elyanow, Rebecca, Pignolet, Beatrice, Falk, Simon, Wünsch, Christian, Deffner, Marie, Yusko, Erik, May, Damon, Mattox, Daniel, Dawin, Eva, Gerdes, Lisa Ann, Bucciarelli, Florence, Revie, Lisa, Antony, Gisela, Jarius, Sven, Seidel, Christiane, Senel, Makbule, Bittner, Stefan, Luessi, Felix, Havla, Joachim, Knop, Matthias, Friese, Manuel A., Rothacher, Susanne, Salmen, Anke, Hayashi, Fumie, Henry, Roland, Caillier, Stacy, Santaniello, Adam, Seipelt, Maria, Heesen, Christoph, Nischwitz, Sandra, Bayas, Antonios, Tumani, Hayrettin, Then Bergh, Florian, Meyer Zu Hörste, Gerd, Kümpfel, Tania, Gross, Catharina C., Wildemann, Brigitte, Kerschensteiner, Martin, Gold, Ralf, Meuth, Sven G., Zipp, Frauke ORCID: https://orcid.org/0000-0002-1231-1928, Cree, Bruce A.C., Oksenberg, Jorge, Wilson, Michael R., Hauser, Stephen L., Zamvil, Scott S., Klotz, Luisa, Liblau, Roland, Robins, Harlan, Sabatino, Joseph J., Wiendl, Heinz and Schwab, Nicholas
EBioMedicine 118 : 105873. August 2025

Deep learning-based body composition analysis from whole-body magnetic resonance imaging to predict all-cause mortality in a large western population.
Jung, M. ORCID: https://orcid.org/0000-0002-1124-4284, Raghu, V.K. ORCID: https://orcid.org/0000-0003-3524-3945, Reisert, M., Rieder, H., Rospleszcz, S., Pischon, T. ORCID: https://orcid.org/0000-0003-1568-767X, Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527, Kauczor, H.U., Völzke, H., Bülow, R., Russe, M.F. ORCID: https://orcid.org/0000-0003-3187-2429, Schlett, C.L., Lu, M.T., Bamberg, F. ORCID: https://orcid.org/0000-0002-7460-3942 and Weiss, J.
EBioMedicine 110 : 105467. December 2024

Neural network-assisted humanisation of COVID-19 hamster transcriptomic data reveals matching severity states in human disease.
Friedrich, V.D., Pennitz, P., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Adler, J.M., Postmus, D., Müller, K., Teixeira Alves, L.G. ORCID: https://orcid.org/0000-0002-5822-4168, Prigann, J., Pott, F., Vladimirova, D., Hoefler, T., Goekeri, C., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Goffinet, C., Saliba, A.E., Scholz, M., Witzenrath, M., Trimpert, J., Kirsten, H. and Nouailles, G.
EBioMedicine 108 : 105312. October 2024

Post-hoc standardisation of parametric T1 maps in cardiovascular magnetic resonance imaging: a proof-of-concept.
Viezzer, D. ORCID: https://orcid.org/0000-0002-1599-3557, Hadler, T. ORCID: https://orcid.org/0000-0002-6151-6858, Gröschel, J. ORCID: https://orcid.org/0000-0002-7268-9041, Ammann, C., Blaszczyk, E. ORCID: https://orcid.org/0000-0001-7370-1690, Kolbitsch, C. ORCID: https://orcid.org/0000-0002-4355-8368, Hufnagel, S., Kranzusch-Groß, R., Lange, S. and Schulz-Menger, J. ORCID: https://orcid.org/0000-0003-3100-1092
EBioMedicine 102 : 105055. April 2024

Lower magnitude and faster waning of antibody responses to SARS-CoV-2 vaccination in anti-TNF-α-treated IBD patients are linked to lack of activation and expansion of cTfh1 cells and impaired B memory cell formation.
Garner-Spitzer, E. ORCID: https://orcid.org/0000-0002-5283-0458, Wagner, A., Gudipati, V., Schoetta, A.M., Orola-Taus, M., Kundi, M., Kunert, R., Mayrhofer, P., Huppa, J.B. ORCID: https://orcid.org/0000-0003-2634-8198, Stockinger, H., Carsetti, R., Gattinger, P., Valenta, R., Kratzer, B. ORCID: https://orcid.org/0000-0003-1091-4327, Sehgal, A.N.A., Pickl, W.F., Reinisch, W., Novacek, G. and Wiedermann, U. ORCID: https://orcid.org/0000-0002-1302-3223
EBioMedicine 96 : 104788. October 2023

Gut microbiome and atrial fibrillation - results from a large population-based study.
Palmu, J. ORCID: https://orcid.org/0000-0003-0059-3347, Börschel, C.S. ORCID: https://orcid.org/0000-0001-9920-0229, Ortega-Alonso, A., Markó, L. ORCID: https://orcid.org/0000-0003-1888-5575, Inouye, M., Jousilahti, P., Salido, R.A., Sanders, K., Brennan, C., Humphrey, G.C., Sanders, J.G., Gutmann, F. ORCID: https://orcid.org/0000-0001-6763-2270, Linz, D., Salomaa, V. ORCID: https://orcid.org/0000-0001-7563-5324, Havulinna, A.S. ORCID: https://orcid.org/0000-0002-4787-8959, Forslund, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Knight, R., Lahti, L., Niiranen, T. and Schnabel, R.B. ORCID: https://orcid.org/0000-0001-7170-9509
EBioMedicine 91 : 104583. May 2023

Association between B-cell depletion and attack risk in neuromyelitis optica spectrum disorder: An exploratory analysis from N-MOmentum, a double-blind, randomised, placebo-controlled, multicentre phase 2/3 trial.
Bennett, J.L., Aktas, O., Rees, W.A., Smith, M.A., Gunsior, M., Yan, L., She, D., Cimbora, D., Pittock, S.J., Weinshenker, B.G., Paul, F. ORCID: https://orcid.org/0000-0002-6378-0070, Marignier, R., Wingerchuk, D., Cutter, G., Green, A., Hartung, H.P., Kim, H.J., Fujihara, K., Levy, M., Katz, E. and Cree, B.A.C.
EBioMedicine 86 : 104321. December 2022

A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: results from the CONKO-005 trial.
Hoyer, K., Hablesreiter, R., Inoue, Y., Yoshida, K., Briest, F., Christen, F., Kakiuchi, N., Yoshizato, T., Shiozawa, Y., Shiraishi, Y., Striefler, J.K., Bischoff, S., Lohneis, P., Putter, H., Blau, O., Keilholz, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Pelzer, U., Hummel, M., Riess, H., Ogawa, S., Sinn, M. and Damm, F.
EBioMedicine 66 : 103327. April 2021

Clinical implications of serum neurofilament in newly diagnosed MS patients: a longitudinal multicentre cohort study.
Bittner, S., Steffen, F., Uphaus, T., Muthuraman, M., Fleischer, V., Salmen, A., Luessi, F., Berthele, A., Klotz, L., Meuth, S.G., Bayas, A., Paul, F. ORCID: https://orcid.org/0000-0002-6378-0070, Hartung, H.P., Linker, R., Heesen, C., Stangel, M., Wildemann, B., Then Bergh, F., Tackenberg, B., Kuempfel, T., Weber, F., Zettl, U.K., Ziemann, U., Tumani, H., Groppa, S., Mühlau, M., Lukas, C., Hemmer, B., Wiendl, H., Gold, R. and Zipp, F.
EBioMedicine 56 : 102807. June 2020

Ketogenic diets attenuate cyclooxygenase and lipoxygenase gene expression in multiple sclerosis.
Bock, M., Karber, M. and Kuhn, H.
EBioMedicine 36 : 293-303. October 2018

Chlamydia trachomatis prevents apoptosis via activation of PDPK1-MYC and enhanced mitochondrial binding of hexokinase II.
Al-Zeer, M.A., Xavier, A., Abu Lubad, M., Sigulla, J., Kessler, M., Hurwitz, R. and Meyer, T.F.
EBioMedicine 23 : 100-110. September 2017

A molecular signature of myalgia in myotonic dystrophy 2.
Moshourab, R. ORCID: https://orcid.org/0000-0002-9180-8472, Palada, V., Grunwald, S. ORCID: https://orcid.org/0000-0002-3899-5424, Grieben, U. ORCID: https://orcid.org/0000-0002-6252-8738, Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352 and Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117
EBioMedicine 7 : 205-211. May 2016

Gut microbiota linked to sexual preference and HIV infection.
Noguera-Julian, M., Rocafort, M., Guillen, Y., Rivera, J., Casadella, M., Nowak, P., Hildebrand, F., Zeller, G., Parera, M., Bellido, R., Rodriguez, C., Carrillo, J., Mothe, B., Coll, J., Bravo, I., Estany, C., Herrero, C., Saz, J., Sirera, G., Torrela, A., Navarro, J., Crespo, M., Brander, C., Negredo, E., Blanco, J., Guarner, F., Calle, M.L., Bork, P. ORCID: https://orcid.org/0000-0002-2627-833X, Soennerborg, A., Clotet, B. and Paredes, R.
EBioMedicine 5 : 135-146. March 2016

Review

Novel targets, treatments, and advanced models for intracerebral haemorrhage.
Zille, M., Farr, T.D., Keep, R.F., Römer, C., Xi, G. and Boltze, J.
EBioMedicine 76 : 103880. 12 February 2022

Editorial

The evolving landscape of cardiometabolic diseases.
Eroglu, T. ORCID: https://orcid.org/0000-0003-3404-2754, Capone, F. ORCID: https://orcid.org/0000-0001-8127-5564 and Schiattarella, G.G. ORCID: https://orcid.org/0000-0002-7582-7171
EBioMedicine 109 : 105447. November 2024