2026

Lipid-facilitated opening of the ADAM10 sheddase revealed by enhanced sampling simulations.
Schahl, Adrien, Haloi, Nandan, Carroni, Marta, Zhang, Shengpan, Sattentau, Quentin James ORCID: https://orcid.org/0000-0001-7170-1937, Sezgin, Erdinc ORCID: https://orcid.org/0000-0002-4915-388X, Delemotte, Lucie and Howard, Rebecca J.
Advanced Science 13 (19): e15713. 2 April 2026

Aberrant SUMOylation restricts the targetable cancer immunopeptidome.
Demel, Uta M. ORCID: https://orcid.org/0000-0002-6480-4185, Meurer, Anna, Zaghla, Badeel Kh Q., Atay, Bilge, Steiert, Daniel, Hummel, Luca V., Isaakidis, Konstandina, Zang, Chuanbing, Korenkov, Michael ORCID: https://orcid.org/0000-0002-2988-8483, Schielin, Marlon, Yousefian, Schayan ORCID: https://orcid.org/0000-0003-0902-0369, Mecklenbräuker, Shima, Kirchner, Marieluise ORCID: https://orcid.org/0000-0002-7049-534X, Haas, Simon ORCID: https://orcid.org/0000-0001-9227-2051, Busse, Antonia ORCID: https://orcid.org/0000-0002-3470-6947, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Müller, Stefan, Wirth, Matthias ORCID: https://orcid.org/0000-0002-8340-0872, Klatt, Martin G. and Keller, Ulrich ORCID: https://orcid.org/0000-0002-8485-1958
Advanced Science 13 (17): e11449. 23 March 2026

2025

Single-cell RNA sequencing delineates renal anti-fibrotic mechanisms mediated by TRPC6 inhibition.
Xu, Yao ORCID: https://orcid.org/0000-0002-3840-9077, Zheng, Zhihuang ORCID: https://orcid.org/0000-0002-5114-3824, Oswald, Marleen Silke, Cheng, Guozhe, Liu, Jun, Zhai, Qidi, Kruegel, Ute, Schaefer, Michael, Gerhardt, Holger ORCID: https://orcid.org/0000-0002-3030-0384, Endlich, Nicole, Gollasch, Maik ORCID: https://orcid.org/0000-0003-2797-1934, Simm, Stefan and Tsvetkov, Dmitry ORCID: https://orcid.org/0000-0002-6472-971X
Advanced Science 12 (33): e01175. 4 September 2025

2024

The networking brain: how extracellular matrix, cellular networks, and vasculature shape the in vivo mechanical properties of the brain.
Bergs, J., Morr, A.S. ORCID: https://orcid.org/0000-0002-0101-1292, Silva, R.V. ORCID: https://orcid.org/0000-0002-8687-2154, Infante-Duarte, C. ORCID: https://orcid.org/0000-0003-3005-351X and Sack, I. ORCID: https://orcid.org/0000-0003-2460-1444
Advanced Science 11 (31): e2402338. 21 August 2024

Efficient recovery of complete gut viral genomes by combined short- and long-read sequencing.
Chen, J., Sun, C., Dong, Y., Jin, M., Lai, S., Jia, L., Zhao, X., Wang, H., Gao, N.L., Bork, P. ORCID: https://orcid.org/0000-0002-2627-833X, Liu, Z., Chen, W.H. ORCID: https://orcid.org/0000-0001-5160-4398 and Zhao, X.M.
Advanced Science 11 (13): 2305818. 3 April 2024

External mechanical stability regulates hematoma vascularization in bone healing rather than endothelial YAP/TAZ mechanotransduction.
Mehl, J. ORCID: https://orcid.org/0000-0002-8279-7142, Farahani, S.K., Brauer, E., Klaus-Bergmann, A. ORCID: https://orcid.org/0000-0002-1164-3322, Thiele, T., Ellinghaus, A., Bartels-Klein, E., Koch, K., Schmidt-Bleek, K., Petersen, A., Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384, Vogel, V. and Duda, G.N. ORCID: https://orcid.org/0000-0001-7605-3908
Advanced Science 11 (13): e2307050. 3 April 2024

2023

Long-read sequencing reveals extensive DNA methylations in human gut phagenome contributed by prevalently phage-encoded methyltransferases.
Sun, C. ORCID: https://orcid.org/0000-0001-5025-2650, Chen, J., Jin, M., Zhao, X., Li, Y., Dong, Y., Gao, N., Liu, Z., Bork, P. ORCID: https://orcid.org/0000-0002-2627-833X, Zhao, X.M. and Chen, W.H. ORCID: https://orcid.org/0000-0001-5160-4398
Advanced Science 10 (25): 2302159. 5 September 2023