Article

Magnetic resonance cartography of renal tubule volume fraction during diuretic intervention.
Tasbihi, Ehsan ORCID: https://orcid.org/0000-0002-4190-7202, Gladytz, Thomas ORCID: https://orcid.org/0000-0003-1072-0098, Millward, Jason M. ORCID: https://orcid.org/0000-0003-4484-2798, Cantow, Kathleen ORCID: https://orcid.org/0000-0002-3907-6315, Seeliger, Erdmann ORCID: https://orcid.org/0000-0002-5685-8044 and Niendorf, Thoralf ORCID: https://orcid.org/0000-0001-7584-6527
Acta Physiologica 241 (9): e70095. September 2025

16/8 intermittent fasting in mice protects from diet-induced obesity by increasing leptin sensitivity and postprandial thermogenesis.
Arruda, A.C. ORCID: https://orcid.org/0000-0003-0788-0154, Santos, R.B., Freitas-Lima, L.C. ORCID: https://orcid.org/0000-0001-9550-6095, Budu, A., Perilhão, M.S., Wasinski, F., Arthur, G.M. ORCID: https://orcid.org/0000-0003-0443-9654, Guzmán, R.R. ORCID: https://orcid.org/0000-0002-1430-1272, Gomes, G., Pesquero, J.B., Mecawi, A.S., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164, Keller, A.C., Donato Junior, J., Festuccia, W.T., Mori, M.A. and Araujo, R.C. ORCID: https://orcid.org/0000-0003-0095-4608
Acta Physiologica 241 (5): e70036. May 2025

Beyond hemoglobin: critical role of 2,3-bisphosphoglycerate mutase in kidney function and injury.
Kulow, V.A. ORCID: https://orcid.org/0000-0002-4226-6697, Roegner, K., Labes, R. ORCID: https://orcid.org/0000-0001-8179-1315, Kasim, M., Mathia, S., Czopek, C.S., Berndt, N., Becker, P.N., Ter-Avetisyan, G., Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199, Enghard, P., Hinze, C., Klocke, J., Eckardt, K.U., Schmidt-Ott, K.M., Persson, P.B., Rosenberger, C. ORCID: https://orcid.org/0000-0003-4194-561X and Fähling, M. ORCID: https://orcid.org/0000-0003-1079-5049
Acta Physiologica 241 (1): e14242. January 2025

Metformin modulates microbiota and improves blood pressure and cardiac remodeling in a rat model of hypertension.
Wimmer, M.I. ORCID: https://orcid.org/0009-0004-5793-0249, Bartolomaeus, H. ORCID: https://orcid.org/0000-0003-4288-3828, Anandakumar, H. ORCID: https://orcid.org/0009-0000-3326-5126, Chen, C.Y. ORCID: https://orcid.org/0000-0003-1765-7132, Vecera, V. ORCID: https://orcid.org/0009-0002-9969-1827, Kedziora, S. ORCID: https://orcid.org/0000-0003-0124-2557, Kamboj, S., Schumacher, F. ORCID: https://orcid.org/0000-0001-8703-3275, Pals, S., Rauch, A. ORCID: https://orcid.org/0000-0002-5152-5830, Meisel, J., Potapenko, O. ORCID: https://orcid.org/0000-0002-4397-568X, Yarritu, A. ORCID: https://orcid.org/0000-0002-1724-0559, Bartolomaeus, T.U.P. ORCID: https://orcid.org/0000-0002-5156-7184, Samaan, M. ORCID: https://orcid.org/0009-0008-5924-3732, Thiele, A. ORCID: https://orcid.org/0000-0003-0786-2239, Stürzbecher, L. ORCID: https://orcid.org/0009-0001-6164-9060, Geisberger, S.Y. ORCID: https://orcid.org/0000-0001-6477-1312, Kleuser, B. ORCID: https://orcid.org/0000-0002-1888-9595, Oefner, P.J. ORCID: https://orcid.org/0000-0002-1499-3977, Haase, N. ORCID: https://orcid.org/0000-0003-0727-1738, Löber, U. ORCID: https://orcid.org/0000-0001-7468-9531, Gronwald, W. ORCID: https://orcid.org/0000-0003-3646-0060, Forslund-Startceva, S.K. ORCID: https://orcid.org/0000-0003-4285-6993, Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644 and Wilck, N. ORCID: https://orcid.org/0000-0003-3189-5364
Acta Physiologica 240 (11): e14226. November 2024

Immunosuppression with cyclosporine versus tacrolimus shows distinctive nephrotoxicity profiles within renal compartments.
Demirci, H. ORCID: https://orcid.org/0000-0001-7730-9653, Popovic, S. ORCID: https://orcid.org/0000-0002-3121-7953, Dittmayer, C., Yilmaz, D.E. ORCID: https://orcid.org/0000-0002-1110-8389, El-Shimy, I.A. ORCID: https://orcid.org/0000-0003-0587-5140, Mülleder, M., Hinze, C., Su, M., Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Osmanodja, B., Paliege, A., Budde, K., Amann, K., Persson, P.B., Mutig, K. and Bachmann, S.
Acta Physiologica 240 (8): e14190. August 2024

Impairment of the adrenergic reserve associated with exercise intolerance in a murine model of heart failure with preserved ejection fraction.
Semmler, L. ORCID: https://orcid.org/0000-0003-2933-7566, Jeising, T., Huettemeister, J., Bathe-Peters, M. ORCID: https://orcid.org/0000-0002-9618-0856, Georgoula, K. ORCID: https://orcid.org/0009-0003-0527-0421, Roshanbin, R., Sander, P., Fu, S., Bode, D., Hohendanner, F., Pieske, B., Annibale, P. ORCID: https://orcid.org/0000-0003-3208-5347, Schiattarella, G.G. ORCID: https://orcid.org/0000-0002-7582-7171, Oeing, C.U. ORCID: https://orcid.org/0000-0002-0816-4443 and Heinzel, F.R. ORCID: https://orcid.org/0000-0002-4529-5282
Acta Physiologica 240 (4): e14124. April 2024

Routing of Kv7.1 to endoplasmic reticulum plasma membrane junctions.
Serrano-Novillo, C., Estadella, I., Navarro-Pérez, M. ORCID: https://orcid.org/0000-0001-8106-9787, Oliveras, A. ORCID: https://orcid.org/0000-0002-5880-5245, de Benito-Bueno, A. ORCID: https://orcid.org/0000-0002-2499-3145, Socuéllamos, P.G. ORCID: https://orcid.org/0000-0001-7097-1708, Bosch, M., Coronado, M.J., Sastre, D., Valenzuela, C. ORCID: https://orcid.org/0000-0003-3929-1960, Soeller, C. ORCID: https://orcid.org/0000-0002-9302-2203 and Felipe, A. ORCID: https://orcid.org/0000-0002-7294-6431
Acta Physiologica 240 (3): e14106. March 2024

Multiple sclerosis and circadian rhythms: Can diet act as a treatment?
Pivovarova-Ramich, O. ORCID: https://orcid.org/0000-0002-3583-8546, Zimmermann, H.G. ORCID: https://orcid.org/0000-0002-0276-8051 and Paul, F. ORCID: https://orcid.org/0000-0002-6378-0070
Acta Physiologica 237 (4): e13939. April 2023

Monitoring kidney size to interpret MRI-based assessment of renal oxygenation in acute pathophysiological scenarios.
Cantow, K. ORCID: https://orcid.org/0000-0002-3907-6315, Gladytz, T. ORCID: https://orcid.org/0000-0003-1072-0098, Millward, J.M. ORCID: https://orcid.org/0000-0003-4484-2798, Waiczies, S. ORCID: https://orcid.org/0000-0002-9916-9572, Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527 and Seeliger, E. ORCID: https://orcid.org/0000-0002-5685-8044
Acta Physiologica 237 (2): e13868. February 2023

Reliable kidney size determination by magnetic resonance imaging in pathophysiological settings.
Gladytz, T. ORCID: https://orcid.org/0000-0003-1072-0098, Millward, J.M. ORCID: https://orcid.org/0000-0003-4484-2798, Cantow, K. ORCID: https://orcid.org/0000-0002-3907-6315, Hummel, L. ORCID: https://orcid.org/0000-0002-6613-6029, Zhao, K. ORCID: https://orcid.org/0000-0003-4769-7477, Flemming, B., Periquito, J.S. ORCID: https://orcid.org/0000-0003-3702-9264, Pohlmann, A. ORCID: https://orcid.org/0000-0002-8572-2568, Waiczies, S. ORCID: https://orcid.org/0000-0002-9916-9572, Seeliger, E. ORCID: https://orcid.org/0000-0002-5685-8044 and Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527
Acta Physiologica 233 (2): e13701. October 2021

Adaptive physiological water conservation explains hypertension and muscle catabolism in experimental chronic renal failure.
Kovarik, J., Morisawa, N., Wild, J., Marton, A., Takase-Minegishi, K., Minegishi, S., Daub, S., Sands, J.M., Klein, J.D., Bailey, J.L., Kovalik, J.P., Rauh, M., Karbach, S., Hilgers, K.F., Luft, F. ORCID: https://orcid.org/0000-0002-8635-1199, Nishiyama, A., Nakano, D., Kitada, K. and Titze, J.
Acta Physiologica 232 (1): e13629. May 2021

Aestivation motifs explain hypertension and muscle mass loss in mice with psoriatic skin barrier defect.
Wild, J. ORCID: https://orcid.org/0000-0002-1446-8101, Jung, R., Knopp, T., Efentakis, P., Benaki, D., Grill, A., Wegner, J., Molitor, M., Garlapati, V., Rakova, N. ORCID: https://orcid.org/0000-0002-5397-6715, Markó, L. ORCID: https://orcid.org/0000-0003-1888-5575, Marton, A. ORCID: https://orcid.org/0000-0002-7702-1577, Mikros, E., Muenzel, T., Kossmann, S., Rauh, M., Nakano, D., Kitada, K., Luft, F. ORCID: https://orcid.org/0000-0002-8635-1199, Waisman, A., Wenzel, P., Titze, J. ORCID: https://orcid.org/0000-0001-8463-8404 and Karbach, S.
Acta Physiologica 232 (1): e13628. May 2021

A synthetic epoxyeicosatrienoic acid analogue prevents the initiation of ischemic acute kidney injury.
Hoff, U. ORCID: https://orcid.org/0000-0002-4814-1780, Bubalo, G., Fechner, M., Blum, M. ORCID: https://orcid.org/0000-0003-3155-0710, Zhu, Y., Pohlmann, A. ORCID: https://orcid.org/0000-0002-8572-2568, Hentschel, J., Arakelyan, K., Seeliger, E. ORCID: https://orcid.org/0000-0002-5685-8044, Flemming, B., Gürgen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Rothe, M. ORCID: https://orcid.org/0000-0002-6813-4705, Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527, Manthati, V.L., Falck, J.R., Haase, M., Schunck, W.H. ORCID: https://orcid.org/0000-0001-7965-7731 and Dragun, D.
Acta Physiologica 227 (2): e13297. October 2019

Acute physical exercise and long-term individual shear rate therapy increase telomerase activity in human peripheral blood mononuclear cells.
Zietzer, A., Buschmann, E.E., Janke, D., Li, L., Brix, M., Meyborg, H., Stawowy, P., Jungk, C., Buschmann, I. and Hillmeister, P.
Acta Physiologica 220 (5): 251-262. June 2017

Sex dependent differences in renal angiotensinogen as an early marker of diabetic nephropathy.
de Alencar Franco Costa, D., Todiras, M. ORCID: https://orcid.org/0000-0002-9373-4753, Campos, L.A., Cipolla-Neto, J., Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164 and Baltatu, O.C.
Acta Physiologica 213 (3): 740-746. March 2015

Functional transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 channels along different segments of the renal vasculature.
Chen, L., Kaßmann, M. ORCID: https://orcid.org/0000-0002-4785-6530, Sendeski, M., Tsvetkov, D. ORCID: https://orcid.org/0000-0002-6472-971X, Marko, L. ORCID: https://orcid.org/0000-0003-1888-5575, Michalick, L., Riehle, M., Wolfgang, L.B., Wolfgang, K.M., Harteneck, C., Tepel, M., Patzak, A. and Gollasch, M. ORCID: https://orcid.org/0000-0003-2797-1934
Acta Physiologica 213 (2): 481-491. February 2015

Leucocyte telomere length as marker for cardiovascular ageing.
Zietzer, A. and Hillmeister, P.
Acta Physiologica 211 (2): 251-256. June 2014

Early effects of an x-ray contrast medium on renal T(2) */T(2) MRI as compared to short-term hyperoxia, hypoxia and aortic occlusion in rats.
Arakelyan, K., Cantow, K. ORCID: https://orcid.org/0000-0002-3907-6315, Hentschel, J., Flemming, B., Pohlmann, A. ORCID: https://orcid.org/0000-0002-8572-2568, Ladwig, M., Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527 and Seeliger, E. ORCID: https://orcid.org/0000-0002-5685-8044
Acta Physiologica 208 (2): 202-213. June 2013

Calprotectin and neutrophil gelatinase-associated lipocalin in the differentiation of pre-renal and intrinsic acute kidney injury.
Seibert, F.S., Pagonas, N., Arndt, R., Heller, F., Dragun, D., Persson, P., Schmidt-Ott, K. ORCID: https://orcid.org/0000-0002-7700-7142, Zidek, W. and Westhoff, T.H.
Acta Physiologica 207 (4): 700-708. April 2013

The Kallikrein-Kinin system.
Hillmeister, P. and Persson, P.B.
Acta Physiologica 206 (4): 215-219. December 2012

Impaired aldosterone responsiveness in Corticosteroid Binding Globulin (CBG) deficient mice.
Sorensen, M.V., Praetorius, H.A., Nykjaer, A., Willnow, T.E. ORCID: https://orcid.org/0000-0001-9515-7921 and Leipziger, J.
Acta Physiologica 201 (1): 169-177. January 2011

Review

Phosphoproteomics for studying signaling pathways evoked by hormones of the renin-angiotensin system: a source of untapped potential.
Souza-Silva, I.M. ORCID: https://orcid.org/0000-0002-6140-3503, Carregari, V.C. ORCID: https://orcid.org/0000-0001-6863-1333, Steckelings, U.M. ORCID: https://orcid.org/0000-0002-5430-4275 and Verano-Braga, T. ORCID: https://orcid.org/0000-0002-7083-2588
Acta Physiologica 241 (2): e14280. February 2025

A gender perspective on diet, microbiome, and sex hormone interplay in cardiovascular disease.
Jovanovic, N. ORCID: https://orcid.org/0000-0001-6300-9705, Zach, V. ORCID: https://orcid.org/0000-0001-9555-0010, Crocini, C. ORCID: https://orcid.org/0000-0001-8231-2726, Bahr, L.S. ORCID: https://orcid.org/0000-0001-7932-8639, Forslund-Startceva, S.K. ORCID: https://orcid.org/0000-0003-4285-6993 and Franz, K. ORCID: https://orcid.org/0000-0002-3819-9671
Acta Physiologica 240 (11): e14228. November 2024

Calcineurin inhibition, cardiovascular consequences, vascular resistance, and potential responses.
Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199
Acta Physiologica 240 (3): e14084. March 2024

Single cell‐ and spatial 'omics revolutionize physiology.
Conrad, T. ORCID: https://orcid.org/0000-0001-5618-6295 and Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521
Acta Physiologica 235 (4): e13848. August 2022

Local cyclic adenosine monophosphate signalling cascades - roles and targets in chronic kidney disease.
Sholokh, A. ORCID: https://orcid.org/0000-0002-1263-2078 and Klussmann, E. ORCID: https://orcid.org/0000-0003-4004-5003
Acta Physiologica 232 (1): e13641. May 2021

Biomarkers and predicting acute kidney injury.
Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199
Acta Physiologica 231 (1): e13479. January 2021

Probing renal blood volume with magnetic resonance imaging.
Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527, Seeliger, E. ORCID: https://orcid.org/0000-0002-5685-8044, Cantow, K. ORCID: https://orcid.org/0000-0002-3907-6315, Flemming, B., Waiczies, S. ORCID: https://orcid.org/0000-0002-9916-9572 and Pohlmann, A. ORCID: https://orcid.org/0000-0002-8572-2568
Acta Physiologica 228 (4): e13435. April 2020

The interstitium conducts extrarenal storage of sodium and represents a third compartment essential for extracellular volume and blood pressure homeostasis.
Wiig, H. ORCID: https://orcid.org/0000-0002-7740-8210, Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199 and Titze, J.
Acta Physiologica 222 (3): e13006. March 2018

Renoprotection: focus on TRPV1, TRPV4, TRPC6 and TRPM2.
Markó, L., Mannaa, M., Haschler, T.N., Krämer, S. and Gollasch, M. ORCID: https://orcid.org/0000-0003-2797-1934
Acta Physiologica 219 (3): 589-612. March 2017

Biomarkers in acute kidney injury - pathophysiological basis and clinical performance.
Schrezenmeier, E.V., Barasch, J., Budde, K., Westhoff, T. and Schmidt-Ott, K.M. ORCID: https://orcid.org/0000-0002-7700-7142
Acta Physiologica 219 (3): 554-572. March 2017

How bold is blood oxygenation level dependent (BOLD) magnetic resonance imaging of the kidney? Opportunities, challenges and future directions.
Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527, Pohlmann, A. ORCID: https://orcid.org/0000-0002-8572-2568, Arakelyan, K., Flemming, B., Cantow, K. ORCID: https://orcid.org/0000-0002-3907-6315, Hentschel, J., Grosenick, D., Ladwig, M., Reimann, H. ORCID: https://orcid.org/0000-0003-1053-9256, Klix, S., Waiczies, S. ORCID: https://orcid.org/0000-0002-9916-9572 and Seeliger, E. ORCID: https://orcid.org/0000-0002-5685-8044
Acta Physiologica 213 (1): 19-38. January 2015

Novel signalling mechanisms and targets in renal ischaemia and reperfusion injury.
Kusch, A. ORCID: https://orcid.org/0000-0002-6666-7081, Hoff, U., Bubalo, G., Zhu, Y., Fechner, M., Schmidt-Ullrich, R. ORCID: https://orcid.org/0000-0002-2472-6530, Marko, L. ORCID: https://orcid.org/0000-0003-1888-5575, Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Schmidt-Ott, K.M. ORCID: https://orcid.org/0000-0002-7700-7142, Gürgen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Blum, M. ORCID: https://orcid.org/0000-0003-3155-0710, Schunck, W.H. ORCID: https://orcid.org/0000-0001-7965-7731 and Dragun, D.
Acta Physiologica 208 (1): 25-40. May 2013

Linking non-invasive parametric MRI with invasive physiological measurements (MR-PHYSIOL): towards a hybrid and integrated approach for investigation of acute kidney injury in rats.
Pohlmann, A. ORCID: https://orcid.org/0000-0002-8572-2568, Cantow, K. ORCID: https://orcid.org/0000-0002-3907-6315, Hentschel, J., Arakelyan, K., Ladwig, M., Flemming, B., Hoff, U., Persson, P.B., Seeliger, E. ORCID: https://orcid.org/0000-0002-5685-8044 and Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527
Acta Physiologica 207 (4): 673-689. April 2013

Neutrophil gelatinase-associated lipocalin: pathophysiology and clinical applications.
Singer, E., Markó, L. ORCID: https://orcid.org/0000-0003-1888-5575, Paragas, N., Barasch, J., Dragun, D., Müller, D.N. ORCID: https://orcid.org/0000-0003-3650-5644, Budde, K. and Schmidt-Ott, K.M. ORCID: https://orcid.org/0000-0002-7700-7142
Acta Physiologica 207 (4): 663-672. April 2013

Transient receptor potential vanilloid 1 (TRPV1), TRPV4, and the kidney.
Kaßmann, M. ORCID: https://orcid.org/0000-0002-4785-6530, Harteneck, C., Zhu, Z., Nürnberg, B., Tepel, M. and Gollasch, M. ORCID: https://orcid.org/0000-0003-2797-1934
Acta Physiologica 207 (3): 546-564. March 2013

Editorial

What's for dinner? Why a close look at diet and microbiota is worthwhile in experimental hypertension research.
Wilck, N. ORCID: https://orcid.org/0000-0003-3189-5364
Acta Physiologica 232 (4): e13704. August 2021

Solute excretion, metabolism, and cardio-renoprotection via two distinct mechanisms revolutionize clinical outcomes.
Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199
Acta Physiologica 232 (3): e13589. 6 July 2021

SARS-CoV-2 effects on the renin-angiotensin-aldosterone system, therapeutic implications.
Ye, Q., Lai, E.Y. ORCID: https://orcid.org/0000-0003-3074-6869, Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199, Persson, P.B. and Mao, J. ORCID: https://orcid.org/0000-0002-6076-3806
Acta Physiologica 231 (4): e13608. April 2021

Did you know? Fluid-and-electrolyte replacement and the uncertainty principle.
Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199
Acta Physiologica 230 (4): e13511. December 2020

Imagine physiology without imaging.
Cantow, K. ORCID: https://orcid.org/0000-0002-3907-6315, Hummel, L., Flemming, B., Waiczies, S. ORCID: https://orcid.org/0000-0002-9916-9572, Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527 and Seeliger, E. ORCID: https://orcid.org/0000-0002-5685-8044
Acta Physiologica 230 (3): e13549. November 2020

Covid-19, ACE2, and the kidney.
Hardenberg, J.H. and Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199
Acta Physiologica 230 (1): e13539. September 2020

Did you know? Why is essential hypertension essential - or is it?
Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199
Acta Physiologica 229 (3): e13469. July 2020

Google maps for tissues: multiscale imaging of biological systems and disease.
Niendorf, T. ORCID: https://orcid.org/0000-0001-7584-6527, Frydman, L., Neeman, M. and Seeliger, E. ORCID: https://orcid.org/0000-0002-5685-8044
Acta Physiologica 228 (2): e13392. February 2020

The role of AKAP12 in coordination of VEGF-induced endothelial cell motility.
Walker-Gray, R. and Klussmann, E. ORCID: https://orcid.org/0000-0003-4004-5003
Acta Physiologica 228 (1): e13359. January 2020