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Genetic deletion of the purinergic receptor P2rx7 worsens the phenotype of α‑sarcoglycan muscular dystrophy.
Astigiano, Cecilia, Principi, Elisa, Pintus, Sara, Benzi, Andrea, Baratto, Serena, Panicucci, Chiara, Passalacqua, Mario, Sierra-Marquez, Juan, Nicke, Annette, Antonini, Francesca, Del Zotto, Genny, Cicatiello, Annunziata Gaetana, Raffaghello, Lizzia, Rezzonico Jost, Tanja, Grassi, Fabio, Bruzzone, Santina, Bruno, Claudio and Gazzerro, Elisabetta
ACS Pharmacology & Translational Science 8
(10): 3477-3489.
10 October 2025
Selectivity and safety characterization of a xanthine-imidazothiazole lead structure: a novel tryptophan hydroxylase inhibitor of peripheral serotonin synthesis.
Wesolowski, R., Schütz, A., Lisurek, M., Nazaré, M., Heinemann, U., Pleimes, D., Bader, M. and Specker, E.
ACS Pharmacology & Translational Science 8
(6): 1678-1693.
13 June 2025
Ligand-specific allosteric coupling controls G-protein-coupled receptor signaling.
Holze, J., Bermudez, M., Pfeil, E.M., Kauk, M., Bödefeld, T., Irmen, M., Matera, C., Dallanoce, C., De Amici, M., Holzgrabe, U., König, G.M., Tränkle, C., Wolber, G., Schrage, R., Mohr, K., Hoffmann, C., Kostenis, E. and Bock, A.
ACS Pharmacology & Translational Science 3
(5): 859-867.
9 October 2020
Review
Viewpoints on the first transatlantic GPCR symposium for early-career investigators.
Bender, B.J., Bock, A., Nesheva, D.N. and Perry-Hauser, N.A.
ACS Pharmacology & Translational Science 4
(5): 1705-1711.
8 October 2021
The European Research Network on Signal Transduction (ERNEST): toward a multidimensional holistic understanding of G protein-coupled receptor signaling.
Sommer, M.E., Selent, J., Carlsson, J., De Graaf, C., Gloriam, D.E., Keseru, G.M., Kosloff, M., Mordalski, S., Rizk, A., Rosenkilde, M.M., Sotelo, E., Tiemann, J.K.S., Tobin, A., Vardjan, N., Waldhoer, M. and Kolb, P.
ACS Pharmacology & Translational Science 3
(2): 361-370.
10 April 2020
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