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Article

Proteolytic processing of the protein tyrosine phosphatase alpha extracellular domain is mediated by ADAM17/TACE.
Kapp, K. and Siemens, J. and Haering, H.U. and Lammers, R.
European Journal of Cell Biology 91 (9): 687-693. September 2012

Sonic hedgehog lineage in the mouse hypothalamus: from progenitor domains to hypothalamic regions.
Alvarez-Bolado, G. and Paul, F.A. and Blaess, S.
Neural Development 7 : 4. 20 January 2012

A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domain.
Bohlen, C.J. and Priel, A. and Zhou, S. and King, D. and Siemens, J. and Julius, D.
Cell 141 (5): 834-845. 28 May 2010

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Trevisani, M. and Siemens, J. and Materazzi, S. and Bautista, D.M. and Nassini, R. and Campi, B. and Imamachi, N. and Andre, E. and Patacchini, R. and Cottrell, G.S. and Gatti, R. and Basbaum, A.I. and Bunnett, N.W. and Julius, D. and Geppetti, P.
Proceedings of the National Academy of Sciences of the United States of America 104 (33): 13519-13524. 14 August 2007

TRPA1 mediates formalin-induced pain.
McNamara, C.R. and Mandel-Brehm, J. and Bautista, D.M. and Siemens, J. and Deranian, K.L. and Zhao, M. and Hayward, N.J. and Chong, J.A. and Julius, D. and Moran, M.M. and Fanger, C.M.
Proceedings of the National Academy of Sciences of the United States of America 104 (33): 13525-13530. 14 August 2007

The menthol receptor TRPM8 is the principal detector of environmental cold.
Bautista, D.M. and Siemens, J. and Glazer, J.M. and Tsuruda, P.R. and Basbaum, A.I. and Stucky, C.L. and Jordt, S.E. and Julius, D.
Nature 448 (7150): 204-208. 12 July 2007

Extracellular domain splice variants of a transforming protein tyrosine phosphatase alpha mutant differentially activate Src-kinase dependent focus formation.
Kapp, K. and Siemens, J. and Weyrich, P. and Schulz, J.B. and Haering, H.U. and Lammers, R.
Genes to Cells 12 (1): 63-73. January 2007

Spider toxins activate the capsaicin receptor to produce inflammatory pain.
Siemens, J.E. and Zhou, S. and Piskorowski, R. and Nikai, T. and Lumpkin, E.A. and Basbaum, A.I. and King, D. and Julius, D.
Nature 444 (7116): 208-212. 9 November 2006

Cadherin 23 is a component of the tip link in hair-cell stereocilia.
Siemens, J. and Lillo, C. and Dumont, R.A. and Reynolds, A. and Williams, D.S. and Gillespie, P.G. and Mueller, U.
Nature 428 (6986): 950-955. 29 April 2004

Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells.
Soellner, C. and Rauch, G.J. and Siemens, J. and Geisler, R. and Schuster, S.C. and Mueller, U. and Nicolson, T.
Nature 428 (6986): 955-959. 29 April 2004

The Usher syndrome proteins cadherin 23 and harmonin form a complex by means of PDZ-domain interactions.
Siemens, J. and Kazmierczak, P. and Reynolds, A. and Sticker, M. and Littlewood-Evans, A. and Mueller, U.
Proceedings of the National Academy of Sciences of the United States of America 99 (23): 14946-14951. 12 November 2002

The sound of silence - diseases that cause deafness and disequilibrium.
Siemens, J. and Littlewood-Evans, A. and Mueller, U.
B.I.F. Futura 16 : 222-228. 2001

Review

Genes, deafness, and balance disorders.
Siemens, J. and Littlewood-Evans, A. and Senften, M. and Mueller, U.
Gene Function and Disease 2 (2-3): 76-82. 2 October 2001

Editorial

Sensory transduction, the gateway to perception: mechanisms and pathology.
Lechner, S.G. and Siemens, J.
EMBO Reports 12 (4): 292-295. 1 April 2011

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