2026
Simultaneous auto-transplant and CD19 CAR T-cell 2nd line therapy followed by CD20 × CD3 bispecific antibody for refractory Burkitt lymphoma, a case report.
Stegemann, Maike 
ORCID: https://orcid.org/0009-0007-3961-9344, Macherndl-Spandl, Sigrid ORCID: https://orcid.org/0009-0007-1247-7948, Mairhofer, Mario ORCID: https://orcid.org/0000-0002-7218-6284, Kaltenbrunner, Sabine ORCID: https://orcid.org/0000-0002-2794-025X, Buxhofer-Ausch, Veronika ORCID: https://orcid.org/0000-0002-7369-9700, Clausen, Johannes ORCID: https://orcid.org/0000-0002-2729-9706, Petzer, Andreas ORCID: https://orcid.org/0000-0003-1595-0300 and Schmitt, Clemens A. ORCID: https://orcid.org/0000-0002-4731-2226
Leukemia & Lymphoma 67
(5): 1147-1151.
April 2026
Patient-specific B-cell lymphoma modeling identifies cooperating genetic alterations and the critical influence of patient context.
Konrath, Fabian ORCID: https://orcid.org/0000-0002-6843-6252, Denker, Sophy ORCID: https://orcid.org/0000-0002-0736-6019, Schmitt, Clemens ORCID: https://orcid.org/0000-0002-4731-2226, Chapuy, Björn ORCID: https://orcid.org/0000-0002-6485-8773 and Wolf, Jana ORCID: https://orcid.org/0000-0003-3254-5868
Research Square
: rs.3.rs-9022766/v1.
12 March 2026
2025
Cell-based immune anticipation of the omicron variant in SARS-CoV-2 triple-vaccinated cancer patients.
Mairhofer, Mario ORCID: https://orcid.org/0000-0002-7218-6284, Kausche, Lea, Kaltenbrunner, Sabine, Pammer, Maria, Ghanem, Riad, Stegemann, Maike and Schmitt, Clemens A. ORCID: https://orcid.org/0000-0002-4731-2226
iScience 28
(11): 113727.
21 November 2025
lncRNA IGFL2-AS1 mediates NSCLC chemoresistance via YBX1-induced HSPA1A/RAP1 activation.
Dong, Hongliang, Xia, Yunxiu, Qi, Jingjing, Liu, Cuilan, Wang, Fei, Cui, Bingjie, Chen, Weiwei, Lv, Wenwen, Zhai, Nailiang, Deng, Jiong, Yu, Yong, Ning, Fangling, Schmitt, Clemens A. ORCID: https://orcid.org/0000-0002-4731-2226 and Du, Jing
Cellular and Molecular Biology Letters 30
(1): 133.
7 November 2025
Chronic stress stimulates protumor macrophage polarization to propel lung cancer progression.
Liu, Cuilan, Du, Hengwei, Yu, Guoxing, Qi, Jingjing, Dong, Hongliang, Hu, Ruiqi, Wang, Fei, Cui, Bingjie, Chen, Weiwei, Zhang, Qian, Li, Chen, Gao, Ran, Schmitt, Clemens A. ORCID: https://orcid.org/0000-0002-4731-2226, Deng, Jiong, Yu, Yong ORCID: https://orcid.org/0000-0003-1928-2514 and Du, Jing
Cancer Research 85
(13): 2429-2447.
2 July 2025
Comparing functional and genomic-based precision medicine in blood cancer patients.
Kazianka, L., Pichler, A., Agreiter, C., Rohrbeck, J., Kornauth, C., Porpaczy, E., Sillaber, C., Sperr, W.R., Gleixner, K.V., Hauswirth, A., Jäger, U., Valent, P., Jonak, C., Porkert, S., Exner, R., Willenbacher, W., Wolf, D., Neumeister, P., Prochazka, K., Deutsch, A., Greil, R., Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Ristl, R., Mayerhoefer, M., Simonitsch-Klupp, I., Pemovska, T. ORCID: https://orcid.org/0000-0003-2951-4905 and Staber, P.B.
HemaSphere 9
(4): e70129.
April 2025
Senescence-associated lineage-aberrant plasticity evokes T-cell-mediated tumor control.
Belenki, D. ORCID: https://orcid.org/0000-0002-9004-9849, Richter-Pechanska, P. ORCID: https://orcid.org/0000-0001-6727-6317, Shao, Z., Bhattacharya, A. ORCID: https://orcid.org/0000-0003-3733-7670, Lau, A., de Freitas, J.A.N.L.F. ORCID: https://orcid.org/0000-0003-3689-765X, Kandler, G., Hick, T.P., Cai, X., Scharnagl, Eva, Bittner, A. ORCID: https://orcid.org/0000-0001-6434-0950, Schönlein, M., Kase, J., Pardon, K., Brzezicha, B., Thiessen, N., Bischof, O. ORCID: https://orcid.org/0000-0003-2422-6277, Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548, Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Du, J., Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Chapuy, B. ORCID: https://orcid.org/0000-0002-6485-8773, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Leser, U., Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868, Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature Communications 16
(1): 3079.
31 March 2025
Persistence and/or senescence: not so lasting at last?
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Cancer Research 85
(1): 7-9.
2 January 2025
2024
Anti-angiogenesis and anti-immunosuppression gene therapy through targeting COUP-TFII in an in situ glioblastoma mouse model.
Wang, F., Zhang, S., Sun, F., Chen, W., Liu, C., Dong, H., Cui, B., Li, L., Sun, C., Du, W., Liu, B., Fan, W., Deng, J., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Wang, X. and Du, J.
Cancer Gene Therapy 31
(8): 1135-1150.
August 2024
LncRNA MIR31HG fosters stemness malignant features of non-small cell lung cancer via H3K4me1- and H3K27Ace-mediated GLI2 expression.
Chen, W., Wang, F., Yu, X., Qi, J., Dong, H., Cui, B., Zhang, Q., Wu, Y., An, J., Ni, N., Liu, C., Han, Y., Zhang, S., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Deng, J. ORCID: https://orcid.org/0000-0002-4489-7556, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514 and Du, J. ORCID: https://orcid.org/0000-0002-2990-3575
Oncogene 43
(18): 1328-1340.
2 May 2024
Cellular senescence: neither irreversible nor reversible.
Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Journal of Experimental Medicine 221
(4): e20232136.
1 April 2024
Passenger gene coamplifications create collateral therapeutic vulnerabilities in cancer.
Bei, Y. ORCID: https://orcid.org/0000-0002-2104-8025, Brame, Luca ORCID: https://orcid.org/0000-0001-5316-2992, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Fritsche-Guenther, R. ORCID: https://orcid.org/0000-0002-6965-0226, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Bhattacharya, A. ORCID: https://orcid.org/0000-0003-3733-7670, Rusu, M.C. ORCID: https://orcid.org/0000-0002-8369-3580, Gürgen, D. ORCID: https://orcid.org/0000-0001-9241-6537, Dubois, F.P.B. ORCID: https://orcid.org/0000-0002-7654-6208, Köppke, J.K.C. ORCID: https://orcid.org/0000-0002-1293-7250, Proba, J. ORCID: https://orcid.org/0009-0006-8293-1248, Wittstruck, N. ORCID: https://orcid.org/0009-0000-4378-3226, Sidorova, O.A. ORCID: https://orcid.org/0009-0004-1459-1662, Chamorro González, R. ORCID: https://orcid.org/0000-0002-5653-7259, Dorado Garcia, H. ORCID: https://orcid.org/0000-0002-2578-3350, Brückner, L. ORCID: https://orcid.org/0000-0002-6155-2277, Xu, R. ORCID: https://orcid.org/0000-0002-5618-246X, Giurgiu, M. ORCID: https://orcid.org/0000-0001-5007-7442, Rodriguez-Fos, E. ORCID: https://orcid.org/0000-0002-2555-0178, Yu, Q. ORCID: https://orcid.org/0000-0002-2151-9624, Spanjaard, B. ORCID: https://orcid.org/0000-0003-1309-8839, Koche, R.P. ORCID: https://orcid.org/0000-0002-6820-5083, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Schulte, J.H. ORCID: https://orcid.org/0000-0003-0671-1201, Eggert, A. ORCID: https://orcid.org/0000-0003-3476-8184, Haase, K. ORCID: https://orcid.org/0000-0002-0944-5618, Kirwan, J. ORCID: https://orcid.org/0000-0002-5423-1651, Hagemann, A.I. ORCID: https://orcid.org/0000-0001-5491-4607, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548 and Henssen, A.G. ORCID: https://orcid.org/0000-0003-1534-778X
Cancer Discovery 14
(3): 492-507.
1 March 2024
2023
Cox proportional hazards deep neural network identifies peripheral blood complete remission to be at least equivalent to morphologic complete remission in predicting outcomes of patients treated with azacitidine - a prospective cohort study by the AGMT.
Pleyer, L. ORCID: https://orcid.org/0000-0002-2790-5067, Vaisband, M., Drost, M., Pfeilstöcker, M., Stauder, R., Heibl, S., Sill, H. ORCID: https://orcid.org/0000-0003-0993-4371, Girschikofsky, M., Stampfl-Mattersberger, M., Pichler, A., Hartmann, B., Petzer, A., Schreder, M., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Vallet, S., Melchardt, T., Zebisch, A., Pichler, P., Zaborsky, N., Machherndl-Spandl, S., Wolf, D., Keil, F., Hasenauer, J., Larcher-Senn, J. and Greil, R.
American Journal of Hematology 98
(11): 1685-1698.
November 2023
Patient-tailored adoptive immunotherapy with EBV-specific T cells from related and unrelated donors.
Bonifacius, A. ORCID: https://orcid.org/0000-0002-0112-967X, Lamottke, B., Tischer-Zimmermann, S., Schultze-Florey, R., Goudeva, L., Heuft, H.G., Arseniev, L., Beier, R., Beutel, G. ORCID: https://orcid.org/0000-0001-6758-6104, Cario, G., Fröhlich, B., Greil, J. ORCID: https://orcid.org/0000-0003-1821-1183, Hansmann, L. ORCID: https://orcid.org/0000-0003-3790-0128, Hasenkamp, J., Höfs, M., Hundsdoerfer, P., Jost, E., Kafa, K., Kriege, O., Kröger, N. ORCID: https://orcid.org/0000-0001-5103-9966, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Meisel, R. ORCID: https://orcid.org/0000-0001-5230-0628, Nathrath, M., Putkonen, M., Ravens, S., Reinhardt, H.C., Sala, E., Sauer, M.G, Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Schroers, R. ORCID: https://orcid.org/0000-0003-2744-5491, Steckel, N.K., Trappe, R.U. ORCID: https://orcid.org/0000-0001-7565-7160, Verbeek, M., Wolff, D. ORCID: https://orcid.org/0000-0001-7015-3190, Blasczyk, R. ORCID: https://orcid.org/0000-0003-3875-3190, Eiz-Vesper, B. and Maecker-Kolhoff, B. ORCID: https://orcid.org/0000-0001-8164-514X
Journal of Clinical Investigation 133
(12): e163548.
15 June 2023
N6-methyladenine-mediated aberrant activation of the lncRNA SOX2OT-GLI1 loop promotes non-small-cell lung cancer stemness.
Dong, Hongliang, Zeng, Lili, Chen, Weiwei, Zhang, Qian, Wang, Fei, Wu, Yan, Cui, Bingjie, Qi, Jingjing, Zhang, Xin, Liu, Cuilan, Deng, Jiong, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Du, Jing ORCID: https://orcid.org/0000-0002-2990-3575
Cell Death Discovery 9
(1): 149.
6 May 2023
Protein biomarkers in blood reflect the interrelationships between stroke outcome, inflammation, coagulation, adhesion, senescence and cancer.
Fuellen, G. ORCID: https://orcid.org/0000-0002-4994-9829, Walter, U., Henze, L., Böhmert, J., Palmer, D., Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Rudolf, H. and Kowald, A.
Cellular and Molecular Neurobiology 43
(4): 1413-1424.
May 2023
COVID-19 and cellular senescence.
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Tchkonia, T., Niedernhofer, L.J., Robbins, P.D. ORCID: https://orcid.org/0000-0003-1068-7099, Kirkland, J.L. ORCID: https://orcid.org/0000-0003-1676-4905 and Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931
Nature Reviews Immunology 23
(4): 251-263.
April 2023
Daratumumab as a novel treatment option in refractory ITP.
Vernava, I. and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Blood Cells Molecules and Diseases 99
: 102724.
March 2023
2022
Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in acute myeloid leukemia.
Gilioli, D., Fusco, S., Tavella, T., Giannetti, K., Conti, A., Santoro, A., Carsana, E., Beretta, S., Schönlein, M., Gambacorta, V., Aletti, F.M., Carraba, M.G., Bonini, C., Ciceri, F., Merelli, I., Vago, L., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Di Micco, R.
bioRxiv
: 2022.11.17.515658.
17 November 2022
A cFLIP-flop switch for senolysis.
Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature Cancer 3
(11): 1279-1281.
November 2022
Senescence and cancer - role and therapeutic opportunities.
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Wang, B. and Demaria, M.
Nature Reviews Clinical oncology 19
(10): 619–636.
October 2022
Simultaneous imaging and flow-cytometry-based detection of multiple fluorescent senescence markers in therapy-induced senescent cancer cells.
Dovjak, E., Mairhofer, M., Wöß, C., Qi, J., Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Yu, Y.
Journal of Visualized Experiments
(185): e63973.
12 July 2022
Evidence for recombinant GRP78, CALR, PDIA3 and GPI as mediators of genetic instability in human CD34+ cells.
Fabarius, A. ORCID: https://orcid.org/0000-0001-5976-2876, Samra, V., Drews, O., Mörz, H., Bierbaum, M., Darwich, A. ORCID: https://orcid.org/0000-0001-9463-9638, Weiss, C., Brendel, S., Kleiner, H., Seifarth, W., Greffrath, W., Hofmann, W.K., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Popp, H.D. ORCID: https://orcid.org/0000-0003-0090-0204
Cancers 14
(12): 2883.
11 June 2022
COVID-19: new disease mechanism is simultaneously a therapeutic target.
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
memo: Magazine of European Medical Oncology 15
(2): 100-101.
June 2022
The genomic and transcriptional landscape of primary central nervous system lymphoma.
Radke, J. ORCID: https://orcid.org/0000-0001-9860-2007, Ishaque, N. ORCID: https://orcid.org/0000-0002-8426-901X, Koll, R., Gu, Z., Schumann, E., Sieverling, L. ORCID: https://orcid.org/0000-0002-0595-4976, Uhrig, S., Hübschmann, D. ORCID: https://orcid.org/0000-0002-6041-7049, Toprak, U.H., López, C., Hostench, X.P. ORCID: https://orcid.org/0000-0003-2089-3777, Borgoni, S., Juraeva, D. ORCID: https://orcid.org/0000-0003-0035-3503, Pritsch, F., Paramasivam, N., Balasubramanian, G.P., Schlesner, M. ORCID: https://orcid.org/0000-0002-5896-4086, Sahay, S., Weniger, M., Pehl, D., Radbruch, H. ORCID: https://orcid.org/0000-0001-6941-3397, Osterloh, A., Korfel, A., Misch, M., Onken, J., Faust, K., Vajkoczy, P., Moskopp, D. ORCID: https://orcid.org/0000-0002-4173-7653, Wang, Y., Jödicke, A., Trümper, L., Anagnostopoulos, I., Lenze, D., Küppers, R. ORCID: https://orcid.org/0000-0002-6691-7191, Hummel, M., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Wiestler, O.D., Wolf, S., Unterberg, A., Eils, R. ORCID: https://orcid.org/0000-0002-0034-4036, Herold-Mende, C., Brors, B. ORCID: https://orcid.org/0000-0001-5940-3101, Siebert, R., Wiemann, S. ORCID: https://orcid.org/0000-0003-4683-3174 and Heppner, F.L. ORCID: https://orcid.org/0000-0001-9816-8917
Nature Communications 13
(1): 2558.
10 May 2022
DLBCL 1L-what to expect beyond R-CHOP?
Stegemann, M., Denker, S. ORCID: https://orcid.org/0000-0002-0736-6019 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Cancers 14
(6): 1453.
11 March 2022
SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Wilke, A.C., Doebele, C., Zindel, A., Lee, K.S. ORCID: https://orcid.org/0000-0001-7682-5736, Rieke, S.A. ORCID: https://orcid.org/0000-0002-2890-1308, Ceribelli, M., Comoglio, F. ORCID: https://orcid.org/0000-0002-8970-6610, Phelan, J.D., Wang, J.Q., Pikman, Y., Jahn, D., Häupl, B., Schneider, C., Scheich, S., Tosto, F.A., Bohnenberger, H. ORCID: https://orcid.org/0000-0003-1038-1030, Stauder, P. ORCID: https://orcid.org/0000-0002-3876-6023, Schnütgen, F. ORCID: https://orcid.org/0000-0002-2426-6685, Slabicki, M., Coulibaly, Z.A., Wolf, S., Bojarczuk, K., Chapuy, B. ORCID: https://orcid.org/0000-0002-6485-8773, Brandts, C.H. ORCID: https://orcid.org/0000-0003-1732-2535, Stroebel, P. ORCID: https://orcid.org/0000-0002-8528-8060, Lewis, C.A., Engelke, M., Xu, X. ORCID: https://orcid.org/0000-0003-1062-2092, Kim, H., Dang, T.H., Schmitz, R. ORCID: https://orcid.org/0000-0002-3348-6807, Hodson, D.J. ORCID: https://orcid.org/0000-0001-6225-2033, Stegmaier, K., Urlaub, H., Serve, H. ORCID: https://orcid.org/0000-0001-8472-5516, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Kreuz, F., Knittel, G. ORCID: https://orcid.org/0000-0001-8395-3701, Rabinowitz, J.D. ORCID: https://orcid.org/0000-0002-1247-4727, Reinhardt, H.C., Vander Heiden, M.G., Thomas, C., Staudt, L.M., Zenz, T. and Oellerich, T. ORCID: https://orcid.org/0000-0001-6570-6125
Blood 139
(4): 538-553.
27 January 2022
Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals.
Denker, S. ORCID: https://orcid.org/0000-0002-0736-6019, Bittner, A. ORCID: https://orcid.org/0000-0001-6434-0950, Frick, M., Kase, J., Hoffmann, J., Trenker, C., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Bogner, C., Hüttmann, A., Dürig, J., Janz, M. ORCID: https://orcid.org/0000-0002-1127-0044, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Marks, R., Krohn, U., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Leukemia & Lymphoma 63
(1): 84-92.
January 2022
2021
Landscape of HER2-low metastatic breast cancer (MBC): results from the Austrian AGMT_MBC-Registry.
Gampenrieder, S.P., Rinnerthaler, G., Tinchon, C., Petzer, A., Balic, M., Heibl, S., Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Zabernigg, A.F., Egle, D., Sandholzer, M., Singer, C.F., Roitner, F., Hager, C., Andel, J., Hubalek, M., Knauer, M. and Greil, R. ORCID: https://orcid.org/0000-0002-4462-3694
Breast Cancer Research 23
(1): 112.
14 December 2021
Cancer stem cells: advances in biology and clinical translation -- a Keystone Symposia report.
Cable, J., Pei, D., Reid, L.M., Wang, X.W., Bhatia, S., Karras, P., Melenhorst, J.J., Grompe, M., Lathia, J.D., Song, E., Kuo, C.J., Zhang, N., White, R.M., Ma, S.K., Ma, L., Chin, Y.R., Shen, M.M., Ng, I.O.L., Kaestner, K.H., Zhou, L., Sikandar, S., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Guo, W., Wong, C.C.L., Ji, J., Tang, D.G., Dubrovska, A., Yang, C., Wiedemeyer, W.R. and Weissman, I.L.
Annals of the New York Academy of Sciences 1506
(1): 142–163.
December 2021
Virus-induced senescence is driver and therapeutic target in COVID-19.
Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Trimpert, J. ORCID: https://orcid.org/0000-0003-1616-0810, Benthani, F. ORCID: https://orcid.org/0000-0002-3283-307X, Mairhofer, M., Richter-Pechanska, P. ORCID: https://orcid.org/0000-0001-6727-6317, Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Belenki, D. ORCID: https://orcid.org/0000-0002-9004-9849, Kaltenbrunner, S., Pammer, M., Kausche, L., Firsching, T.C. ORCID: https://orcid.org/0000-0003-1378-4951, Dietert, K., Schotsaert, M., Martínez-Romero, C. ORCID: https://orcid.org/0000-0001-8888-7715, Singh, G. ORCID: https://orcid.org/0000-0003-3260-2631, Kunz, S. ORCID: https://orcid.org/0000-0002-0131-3506, Niemeyer, D. ORCID: https://orcid.org/0000-0002-1897-6365, Ghanem, R., Salzer, H.J.F., Paar, C., Mülleder, M., Uccellini, M., Michaelis, E.G., Khan, A., Lau, A., Schönlein, M. ORCID: https://orcid.org/0000-0003-3156-3132, Habringer, A., Tomasits, J., Adler, J.M., Kimeswenger, S. ORCID: https://orcid.org/0000-0002-0443-8558, Gruber, A.D. ORCID: https://orcid.org/0000-0002-4502-0393, Hoetzenecker, W., Steinkellner, H., Purfuerst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Motz, R., Di Pierro, F., Lamprecht, B. ORCID: https://orcid.org/0000-0003-3365-3449, Osterrieder, N., Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Drosten, C. ORCID: https://orcid.org/0000-0001-7923-0519, García-Sastre, A. ORCID: https://orcid.org/0000-0002-6551-1827, Langer, R., Ralser, M., Eils, R. ORCID: https://orcid.org/0000-0002-0034-4036, Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature 599
(7884): 283-289.
11 November 2021
Capecitabine in combination with bendamustine in pretreated women with HER2-negative metastatic breast cancer: results of a phase II trial (AGMT MBC-6).
Rinnerthaler, G., Gampenrieder, S.P. ORCID: https://orcid.org/0000-0002-3966-1071, Petzer, A., Hubalek, M., Petru, E., Sandholzer, M., Andel, J., Balic, M., Melchardt, T., Hauser-Kronberger, C., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Ulmer, H. and Greil, R.
Therapeutic Advances in Medical Oncology 13
: 17588359211042301.
19 October 2021
Therapy-induced senescence: opportunities to improve anticancer therapy.
Prasanna, P.G. ORCID: https://orcid.org/0000-0001-8386-926X, Citrin, D.E. ORCID: https://orcid.org/0000-0002-4391-2734, Hildesheim, J., Ahmed, M.M., Venkatachalam, S., Riscuta, G., Xi, D., Zheng, G. ORCID: https://orcid.org/0000-0002-8106-6663, van Deursen, J., Goronzy, J. ORCID: https://orcid.org/0000-0001-7670-1856, Kron, S.J. ORCID: https://orcid.org/0000-0003-1518-2436, Anscher, M.S., Sharpless, N.E. ORCID: https://orcid.org/0000-0001-7078-9455, Campisi, J. ORCID: https://orcid.org/0000-0001-6858-9462, Brown, S.L., Niedernhofer, L.J., O'Loghlen, A., Georgakilas, A.G. ORCID: https://orcid.org/0000-0002-5971-0010, Paris, F. ORCID: https://orcid.org/0000-0002-0176-7348, Gius, D., Gewirtz, D.A. ORCID: https://orcid.org/0000-0003-0437-4934, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Abazeed, M.E. ORCID: https://orcid.org/0000-0002-6614-4440, Kirkland, J.L. ORCID: https://orcid.org/0000-0003-1676-4905, Richmond, A. ORCID: https://orcid.org/0000-0002-9580-900X, Romesser, P.B. ORCID: https://orcid.org/0000-0001-8268-2903, Lowe, S.W., Gil, J. ORCID: https://orcid.org/0000-0002-4303-6260, Mendonca, M.S. ORCID: https://orcid.org/0000-0001-9139-1964, Burma, S., Zhou, D. and Coleman, C.N.
Journal of the National Cancer Institute 113
(10): 1285-1298.
October 2021
MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.
Brägelmann, J. ORCID: https://orcid.org/0000-0002-1306-2169, Lorenz, C., Borchmann, S., Nishii, K., Wegner, J. ORCID: https://orcid.org/0000-0001-8103-8040, Meder, L., Ostendorp, J., Ast, D.F., Heimsoeth, A., Nakasuka, T., Hirabae, A., Okawa, S., Dammert, M.A. ORCID: https://orcid.org/0000-0003-4269-7822, Plenker, D. ORCID: https://orcid.org/0000-0003-3895-4064, Klein, S., Lohneis, P. ORCID: https://orcid.org/0000-0002-4797-0018, Gu, J., Godfrey, L.K., Forster, J., Trajkovic-Arsic, M., Zillinger, T. ORCID: https://orcid.org/0000-0002-0866-4835, Haarmann, M., Quaas, A., Lennartz, S., Schmiel, M., D'Rozario, J. ORCID: https://orcid.org/0000-0002-3380-4801, Thomas, E.S., Li, H. ORCID: https://orcid.org/0000-0002-4673-1234, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, George, J. ORCID: https://orcid.org/0000-0002-4272-3683, Thomas, R.K., von Karstedt, S. ORCID: https://orcid.org/0000-0002-7816-5919, Hartmann, G. ORCID: https://orcid.org/0000-0003-1021-2018, Büttner, R. ORCID: https://orcid.org/0000-0001-8806-4786, Ullrich, R.T., Siveke, J.T. ORCID: https://orcid.org/0000-0002-8772-4778, Ohashi, K., Schlee, M. ORCID: https://orcid.org/0000-0003-3671-7639 and Sos, M.L. ORCID: https://orcid.org/0000-0002-2868-100X
Nature Communications 12
(1): 5505.
17 September 2021
Humoral and cellular immune responses in SARS-CoV-2 mRNA-vaccinated patients with cancer.
Mairhofer, M., Kausche, L., Kaltenbrunner, S., Ghanem, R., Stegemann, M., Klein, K., Pammer, M., Rauscher, I., Salzer, H.J.F., Doppler, S., Habringer, A., Paar, C., Kimeswenger, S., Hoetzenecker, W., Lamprecht, B., Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Cancer Cell 39
(9): 1171-1172.
13 September 2021
Cerebral EBV-positive PTLD controlled by PD-1 checkpoint blockade in a liver transplant patient.
Bittner, A. ORCID: https://orcid.org/0000-0001-6434-0950, Radke, J., Eurich, D., Wiener, E., Denker, S. ORCID: https://orcid.org/0000-0002-0736-6019, Anagnostopoulos, I., Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Heppner, F.L., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Leukemia & Lymphoma 62
(8): 2026-2029.
August 2021
Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas.
Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Schrezenmeier, J.F. ORCID: https://orcid.org/0000-0001-5239-4513, Richter-Pechanska, P. ORCID: https://orcid.org/0000-0001-6727-6317, Dolnik, A., Hick, T.P., Schleich, K., Cai, X., Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076, Lohneis, P., Masswig, S., Denker, S. ORCID: https://orcid.org/0000-0002-0736-6019, Busse, A. ORCID: https://orcid.org/0000-0002-3470-6947, Knittel, G., Flümann, R., Childs, D., Childs, L., Gätjens-Sanchez, A.M., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Rosenwald, A., Reinhardt, H.C. and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Blood 137
(20): 2785-2899.
20 May 2021
Transcriptional repression of NFKBIA triggers constitutive IKK- and proteasome-independent p65/RelA activation in senescence.
Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061, Mikuda, N., Höpken, U.E. ORCID: https://orcid.org/0000-0002-0776-4893, Kärgel, E., Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Tufan, A.B. ORCID: https://orcid.org/0000-0002-8734-9736, Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Sun, W. ORCID: https://orcid.org/0000-0001-9607-1361, Krahn, I., Schleich, K., von Hoff, L., Hinz, M. ORCID: https://orcid.org/0000-0003-2611-4121, Willenbrock, M., Jungmann, S., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Schmidt-Ullrich, R. ORCID: https://orcid.org/0000-0002-2472-6530, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
EMBO Journal 40
(6): e104296.
15 March 2021
An autochthonous mouse model of Myd88- and BCL2-driven diffuse large B-cell lymphoma reveals actionable molecular vulnerabilities.
Flümann, R., Rehkämper, T., Nieper, P., Pfeiffer, P., Holzem, A., Klein, S., Bhatia, S., Kochanek, M., Kisis, I., Pelzer, B.W., Ahlert, H., Hauer, J., da Palma Guerreiro, A., Ryan, J.A., Reimann, M., Riabinska, A., Wiederstein, J., Krüger, M., Deckert, M., Altmüller, J. ORCID: https://orcid.org/0000-0003-4372-1521, Klatt, A.R., Frenzel, L.P., Pasqualucci, L., Béguelin, W., Melnick, A.M., Sander, S., Montesinos-Rongen, M., Brunn, A., Lohneis, P., Büttner, R., Kashkar, H., Borkhardt, A., Letai, A., Persigehl, T., Peifer, M., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Reinhardt, H.C. and Knittel, G.
Blood Cancer Discovery 2
(1): 70-91.
January 2021
2020
Clinical outcome in patients with carcinoma of the esophagogastric junction treated with neoadjuvant radiochemotherapy or perioperative chemotherapy: a two-enter retrospective analysis.
Wundsam, H.V., Doleschal, B., Prommer, R., Venhoda, C., Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Petzer, A., Metz-Gercek, S. and Rumpold, H.
Oncology 98
(10): 706-713.
October 2020
ABVD vs BEACOPP escalated in advanced-stage Hodgkin's lymphoma: Results from a multicenter European study.
Mondello, P. ORCID: https://orcid.org/0000-0002-0355-3757, Musolino, C., Dogliotti, I., Bohn, J.P. ORCID: https://orcid.org/0000-0002-2066-7377, Cavallo, F., Ferrero, S., Botto, B., Cerchione, C., Nappi, D., De Lorenzo, S., Martinelli, G., Wolf, D., Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Loseto, G., Cuzzocrea, S., Willenbacher, W., Mian, M. ORCID: https://orcid.org/0000-0003-2539-5996 and Straus, D.J.
American Journal of Hematology 95
(9): 1030-1037.
September 2020
H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients.
Schleich, K., Kase, J., Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548, Trescher, S., Bhattacharya, A. ORCID: https://orcid.org/0000-0003-3733-7670, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Wailes, E.M., Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076, Lohneis, P., Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Lau, A., Lenze, D., Hummel, M., Chapuy, B., Leser, U., Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature Communications 11
(1): 3651.
20 July 2020
AP-1 imprints a reversible transcriptional programme of senescent cells.
Martínez-Zamudio, R.I. ORCID: https://orcid.org/0000-0001-9202-4285, Roux, P.F., de Freitas, J.A.N.L.F. ORCID: https://orcid.org/0000-0003-3689-765X, Robinson, L., Doré, G., Sun, B. ORCID: https://orcid.org/0000-0002-8963-4100, Belenki, D. ORCID: https://orcid.org/0000-0002-9004-9849, Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Herbig, U., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Gil, J. ORCID: https://orcid.org/0000-0002-4303-6260 and Bischof, O. ORCID: https://orcid.org/0000-0003-2422-6277
Nature Cell Biology 22
(7): 842-855.
July 2020
ASH highlights 2019: "aggressive B-cell lymphoma".
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
memo: Magazine of European Medical Oncology 13
(3): 266-269.
20 May 2020
Local and central evaluation of HER2 positivity and clinical outcome in advanced gastric and gastroesophageal cancer: results from the AGMT GASTRIC-5 Registry.
Huemer, F., Weiss, L. ORCID: https://orcid.org/0000-0002-2174-5613, Regitnig, P. ORCID: https://orcid.org/0000-0002-1371-1595, Winder, T., Hartmann, B., Thaler, J., Piringer, G., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Eisterer, W., Gänzer, H., Wüstner, Al., Andel, J., Jagdt, B., Ulmer, H., Greil, R. ORCID: https://orcid.org/0000-0002-4462-3694 and Wöll, E.
Journal of Clinical Medicine 9
(4): 935.
29 March 2020
Ensuring center quality, proper patient selection and fair access to chimeric antigen receptor T-cell therapy: position statement of the Austrian CAR-T Cell Network.
Greinix, H.T., Attarbaschi, A., Girschikofsky, M., Greil, R., Holter, W., Neumeister, P., Peters, C., Petzer, A., Rudzki, J., Schlenke, P., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Schwinger, W., Wolf, D., Worel, N. and Jaeger, U.
memo: Magazine of European Medical Oncology 13
(1): 27-31.
March 2020
2019
A Phase I/II first-line study of R-CHOP plus B-cell receptor/NF-κB-double-targeting to molecularly assess therapy response.
Denker, S. ORCID: https://orcid.org/0000-0002-0736-6019, Bittner, A. ORCID: https://orcid.org/0000-0001-6434-0950, Na, I.K. ORCID: https://orcid.org/0000-0001-9902-5424, Kase, J., Frick, M., Anagnostopoulos, I., Hummel, M. and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
International Journal of Hematologic Oncology 8
(4): IJH20.
19 December 2019
Cellular senescence: defining a path forward.
Gorgoulis, V., Adams, P.D., Alimonti, A., Bennett, D.C., Bischof, O., Bishop, C., Campisi, J., Collado, M., Evangelou, K., Ferbeyre, G., Gil, J., Hara, E., Krizhanovsky, V., Jurk, D., Maier, A.B., Narita, M., Niedernhofer, L., Passos, J.F., Robbins, P.D., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Sedivy, J., Vougas, K., von Zglinicki, T., Zhou, D., Serrano, M. and Demaria, M.
Cell 179
(4): 813-827.
31 October 2019
Non-invasive metastasis prognosis from plasma metabolites in stage II colorectal cancer patients: the DACHS study.
Zaimenko, I. ORCID: https://orcid.org/0000-0002-4581-349X, Jaeger, C., Brenner, H., Chang-Claude, J., Hoffmeister, M., Grötzinger, C., Detjen, K., Burock, S., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X and Lisec, J.
International Journal of Cancer 145
(1): 221-231.
1 July 2019
HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion.
Gong, M. ORCID: https://orcid.org/0000-0001-7384-3429, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Liang, L., Vuralli, D., Froehler, S. ORCID: https://orcid.org/0000-0001-8000-2927, Kuehnen, P. ORCID: https://orcid.org/0000-0003-0211-176X, Du Bois, P., Zhang, J., Cao, A., Liu, Y., Hussain, K., Fielitz, J. ORCID: https://orcid.org/0000-0001-8522-1045, Jia, S. ORCID: https://orcid.org/0000-0001-8595-9314, Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627 and Raile, K. ORCID: https://orcid.org/0000-0002-0842-1737
Molecular Genetics & Genomic Medicine 7
(5): e602.
May 2019
Editorial: critical issues in lymphoma management.
Fuchs, D. ORCID: https://orcid.org/0000-0002-9968-1576 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
memo: Magazine of European Medical Oncology 12
(1): 1.
March 2019
Epigenetic co-deregulation of EZH2/TET1 is a senescence-countering, actionable vulnerability in triple-negative breast cancer.
Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Qi, J., Xiong, J. ORCID: https://orcid.org/0000-0002-4302-3515, Jiang, L., Cui, D., He, J., Chen, P., Li, L., Wu, C., Ma, T., Shao, S., Wang, J., Yu, D., Zhou, B., Huang, D., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Tao, R.
Theranostics 9
(3): 761-777.
24 January 2019
The dynamic nature of senescence in cancer.
Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature Cell Biology 21
(1): 94-101.
January 2019
Genotoxic stress-induced senescence.
Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Methods in Molecular Biology 1896
: 93-105.
2019
2018
The Senescence-Stemness Alliance - a cancer-hijacked regeneration principle.
Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Trends in Cell Biology 28
(12): 1049-1061.
December 2018
Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis.
Arends, C.M., Galan-Sousa, J., Hoyer, K., Chan, W., Jäger, M., Yoshida, K., Seemann, R., Noerenberg, D., Waldhueter, N., Fleischer-Notter, H., Christen, F., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Pelzer, U., Sinn, M., Zemojtel, T., Ogawa, S., Märdian, S., Schreiber, A. ORCID: https://orcid.org/0000-0003-1244-6379, Kunitz, A., Krüger, U., Bullinger, L. ORCID: https://orcid.org/0000-0002-5890-5510, Mylonas, E., Frick, M. and Damm, F.
Leukemia 32
(9): 1908-1919.
September 2018
UnSASPing senescence: unmasking tumor suppression?
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Cancer Cell 34
(1): 6-8.
9 July 2018
Nontargeted identification of tracer incorporation in high-resolution mass spectrometry.
Hoffmann, F., Jaeger, C., Bhattacharya, A. ORCID: https://orcid.org/0000-0003-3733-7670, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Lisec, J.
Analytical Chemistry 90
(12): 7253-7260.
19 June 2018
Targeting the senescence-overriding cooperative activity of structurally unrelated H3K9 demethylases in melanoma.
Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Schleich, K., Yue, B., Ji, S., Lohneis, P., Kemper, K., Silvis, M.S., Qutob, N., van Rooijen, E., Werner-Klein, M., Li, L., Dhawan, D. ORCID: https://orcid.org/0000-0003-3005-7772, Meierjohann, S., Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Elkahloun, A., Treitschke, S., Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Speck, C., Mallette, F.A., Zon, L.I., Holmen, S.L., Peeper, D.S., Samuels, Y., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931
Cancer Cell 33
(2): 322-336.
12 February 2018
Senescence-associated reprogramming promotes cancer stemness.
Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076, Belenki, D. ORCID: https://orcid.org/0000-0002-9004-9849, Däbritz, J.H.M., Zhao, Z., Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548, Dimitrova, L., Lenze, D., Monteiro Barbosa, I.A., Mendoza-Parra, M.A., Kanashova, T. ORCID: https://orcid.org/0000-0001-8841-5785, Metzner, M., Pardon, K., Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Trumpp, A., Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Zuber, J., Gronemeyer, H., Hummel, M., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature 553
(7686): 96-100.
4 January 2018
2017
The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity.
El-Athman, R., Genov, N.N., Mazuch, J., Zhang, K., Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Fuhr, L., Abreu, M., Li, Y., Wallach, T., Kramer, A., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Relógio, A. ORCID: https://orcid.org/0000-0002-9165-2439
PLoS Biology 15
(12): e2002940.
7 December 2017
Decitabine inhibits T cell proliferation via a novel TET2-dependent mechanism and exerts potent protective effect in mouse auto- and allo-immunity models.
Wang, X., Wang, J., Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Ma, T., Chen, P., Zhou, B. and Tao, R.
Oncotarget 8
(34): 56802-56815.
22 August 2017
Compound annotation in liquid chromatography/high-resolution mass spectrometry based metabolomics: robust adduct ion determination as a prerequisite to structure prediction in electrospray ionization mass spectra.
Jaeger, C. ORCID: https://orcid.org/0000-0001-7596-6262, Méret, M., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Lisec, J.
Rapid Communications in Mass Spectrometry 31
(15): 1261-1266.
15 August 2017
EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.
Young, E., Noerenberg, D., Mansouri, L., Ljungström, V., Frick, M., Sutton, L.A., Blakemore, S.J., Galan-Sousa, J., Plevova, K., Baliakas, P., Rossi, D., Clifford, R., Roos-Weil, D., Navrkalova, V., Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Smedby, K.E., Juliusson, G., Giacopelli, B., Blachly, J.S., Belessi, C., Panagiotidis, P., Chiorazzi, N., Davi, F., Langerak, A.W., Oscier, D., Schuh, A., Gaidano, G., Ghia, P., Xu, W., Fan, L., Bernard, O.A., Nguyen-Khac, F., Rassenti, L., Li, J., Kipps, T.J., Stamatopoulos, K., Pospisilova, S., Zenz, T., Oakes, C.C., Strefford, J.C., Rosenquist, R. and Damm, F.
Leukemia 31
(7): 1547-1554.
July 2017
Initiation of acute graft-versus-host disease by angiogenesis.
Riesner, K., Shi, Y., Jacobi, A., Kräter, M., Kalupa, M., McGearey, A., Mertlitz, S., Cordes, S., Schrezenmeier, J.F. ORCID: https://orcid.org/0000-0001-5239-4513, Mengwasser, J., Westphal, S., Perez-Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Guck, J. and Penack, O.
Blood 129
(14): 2021-2032.
6 April 2017
Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin's lymphoma.
Du, J., Neuenschwander, M. ORCID: https://orcid.org/0000-0002-3114-7975, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Däbritz, J.H.M., Neuendorff, N.R., Schleich, K., Bittner, A. ORCID: https://orcid.org/0000-0001-6434-0950, Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Beuster, G., Radetzki, S. ORCID: https://orcid.org/0000-0003-2688-2868, Specker, E. ORCID: https://orcid.org/0000-0002-9471-9520, Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Rosenbauer, F. ORCID: https://orcid.org/0000-0001-7977-9421, Mathas, S. ORCID: https://orcid.org/0000-0001-9626-1413, Lohneis, P., Hummel, M., Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Blood 129
(1): 71-81.
5 January 2017
Detecting markers of therapy-induced senescence in cancer cells.
Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Methods in Molecular Biology 1534
: 41-52.
2017
2016
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
Mansouri, L., Noerenberg, D., Young, E., Mylonas, E., Abdulla, M., Frick, M., Asmar, F., Ljungstroem, V., Schneider, M., Yoshida, K., Skaftason, A., Pandzic, T., Gonzalez, B., Tasidou, A., Waldhueter, N., Rivas-Delgado, A., Angelopoulou, M., Ziepert, M., Arends, C.M., Couronne, L., Lenze, D., Baldus, C.D., Bastard, C., Okosun, J., Fitzgibbon, J., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Drexler, H.G., Roos-Weil, D., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Munch-Petersen, H.D., Zenz, T., Hansmann, M.L., Strefford, J.C., Enblad, G., Bernard, O.A., Ralfkiaer, E., Erlanson, M., Korkolopoulou, P., Hultdin, M., Papadaki, T., Gronbaek, K., Lopez-Guillermo, A., Ogawa, S., Kueppers, R., Stamatopoulos, K., Stavroyianni, N., Kanellis, G., Rosenwald, A., Campo, E., Amini, R.M., Ott, G., Vassilakopoulos, T.P., Hummel, M., Rosenquist, R. and Damm, F.
Blood 128
(23): 2666-2670.
15 December 2016
Automated annotation and evaluation of in-source mass spectra in GC/atmospheric pressure chemical ionization-MS-based metabolomics.
Jaeger, C., Hoffmann, F., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Lisec, J.
Analytical Chemistry 88
(19): 9386-9390.
4 October 2016
New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals.
Qi, J., Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Akilli Öztürk, Ö., Holland, J.D., Besser, D. ORCID: https://orcid.org/0000-0002-4958-9624, Fritzmann, J., Wulf-Goldenberg, A., Eckert, K., Fichtner, I. and Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829
Gut 65
(10): 1690-1701.
October 2016
The persistent dynamic secrets of senescence.
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature Cell Biology 18
(9): 913-915.
September 2016
Extending the dynamic range in metabolomics experiments by automatic correction of peaks exceeding the detection limit.
Lisec, J., Hoffmann, F., Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226 and Jaeger, C.
Analytical Chemistry 88
(15): 7487-7492.
2 August 2016
B cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B cell lymphoma in mice.
Knittel, G., Liedgens, P., Korovkina, D., Seeger, J.M., Al-Baldawi, Y., Al-Maarri, M., Fritz, C., Vlantis, K., Bezhanova, S., Scheel, A.H., Wolz, O.O., Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Möller, P., López, C., Schlesner, M., Lohneis, P., Weber, A.N.R., Trümper, L., Staudt, L.M., Ortmann, M., Pasparakis, M., Siebert, R., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Klatt, A.R., Wunderlich, F.T., Schäfer, S.C., Persigehl, T., Montesinos-Rongen, M., Odenthal, M., Büttner, R., Frenzel, L.P., Kashkar, H. and Reinhardt, H.C.
Blood 127
(22): 2732-2741.
2 June 2016
CD20-targeting immunotherapy promotes cellular senescence in B-cell lymphoma.
Däbritz, J.H.M., Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Schönlein, M., Rosenfeldt, M.T., Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548, Kaufmann, A.M., Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Molecular Cancer Therapeutics 15
(5): 1074-1081.
May 2016
T cell PTLD successfully treated with single-agent brentuximab vedotin first-line therapy.
Choi, M. ORCID: https://orcid.org/0000-0002-0286-1491, Fink, S., Prasad, V., Anagnostopoulos, I., Reinke, P. and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Transplantation 100
(3): e8-e10.
March 2016
Metabolism in cancer.
Cramer, T. and Schmitt, C., eds.
Recent Results in Cancer Research, 207
.
Springer.
ISBN 978-3-319-42118-6
2016
Neutropenic sepsis in the ICU: Outcome predictors in a two-phase model and microbiology findings.
Kruse, J.M., Jenning, T., Rademacher, S., Arnold, R., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Jörres, A., Enghard, P. and Oppert, M.
Critical Care Research and Practice 2016
: 8137850.
2016
2015
Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling.
Hu, F., a Dzaye, O.D., Hahn, A., Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Scavetta, R.J., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Kaczmarek, A.K., Dunning, K.R., Ricciardelli, C., Rinnenthal, J.L., Heppner, F.L., Lehnardt, S., Synowitz, M., Wolf, S.A. ORCID: https://orcid.org/0000-0003-0922-8418 and Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291
Neuro-Oncology 17
(2): 200-210.
February 2015
2014
Mouse models of human cancer.
Böck, B.C., Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Augustin, H.G.
Cancer Research 74
(17): 4671-4675.
1 September 2014
NF-κB in cellular senescence and cancer treatment.
Jing, H. and Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931
Molecules and Cells 37
(3): 189-195.
31 March 2014
2013
Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548, Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Beuster, G., Zasada, C. ORCID: https://orcid.org/0000-0003-1547-8317, Däbritz, J.H.M., Lisec, J., Lenze, D., Gerhardt, A., Schleicher, K., Kratzat, S., Purfürst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Walenta, S., Mueller-Klieser, W., Gräler, M., Hummel, M., Keller, U. ORCID: https://orcid.org/0000-0002-8485-1958, Buck, A.K., Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Willmitzer, L., Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Kempa, S. ORCID: https://orcid.org/0000-0002-0696-9299, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature 501
(7467): 421-425.
19 September 2013
Combined inhibition of PI3K-related DNA-damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas.
Shortt, J., Martin, B.P., Newbold, A., Hannan, K.M., Devlin, J.R., Baker, A.J., Ralli, R., Cullinane, C., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Hall, M.N., Wall, M., Hannan, R.D., Pearson, R.B., McArthur, G.A. and Johnstone, R.W.
Blood 121
(15): 2964-2974.
11 April 2013
2012
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.
Bywater, M.J., Poortinga, G., Sanij, E., Hein, N., Peck, A., Cullinane, C., Wall, M., Cluse, L., Drygin, D., Anderes, K., Huser, N., Proffitt, C., Bliesath, J., Haddach, M., Schwaebe, M.K., Ryckman, D.M., Rice, W.G., Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Lowe, S.W., Johnstone, R.W., Pearson, R.B., McArthur, G.A. and Hannan, R.D.
Cancer Cell 22
(1): 51-65.
10 July 2012
Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice.
Gerbitz, A., Sukumar, M., Helm, F., Wilke, A., Friese, C., Fahrenwaldt, C., Lehmann, F.M., Loddenkemper, C., Kammertoens, T. ORCID: https://orcid.org/0000-0003-3309-5141, Mautner, J., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Blankenstein, T. ORCID: https://orcid.org/0000-0002-3357-4321 and Bornkamm, G.W.
PLoS ONE 7
(3): e34552.
30 March 2012
Reduced tumor-antigen density leads to PD-1/PD-L1 mediated impairment of partially exhausted CD8(+) T cells.
Kaiser, A.D., Schuster, K., Gadiot, J., Borkner, L., Daebritz, H., Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Andreesen, R. and Blank, C.
European Journal of Immunology 42
(3): 662-671.
March 2012
2011
The Myc/macrophage tango: Oncogene-induced senescence, Myc style.
Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128
Seminars in Cancer Biology 21
(6): 377-384.
December 2011
Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations.
Jing, H., Kase, J., Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548, Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Lenze, D., Grau, M., Beuster, G., Ji, S., Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Lenz, P., Hummel, M., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Lenz, G., Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931
Genes & Development 25
(20): 2137-2146.
15 October 2011
Non-cell-autonomous tumor suppression: oncogene-provoked apoptosis promotes tumor cell senescence via stromal crosstalk.
Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931
Journal of Molecular Medicine 89
(9): 869-875.
September 2011
2010
Cellular senescence predicts treatment outcome in metastasised colorectal cancer.
Haugstetter, A.M., Loddenkemper, C., Lenze, D., Groene, J., Standfuss, C., Petersen, I., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
British Journal of Cancer 103
(4): 505-509.
10 August 2010
Hypoxia-inducible factor 1α determines gastric cancer chemosensitivity via modulation of p53 and NF-κB.
Rohwer, N., Dame, C., Haugstetter, A.M., Wiedenmann, B., Detjen, K., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Cramer, T.
PLoS ONE 5
(8): e12038.
10 August 2010
Tumor stroma-derived TGF-beta limits Myc-driven lymphomagenesis via Suv39h1-dependent senescence.
Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Loddenkemper, C., Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548, Tabor, V., Aichele, P., Stein, H., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Jenuwein, T. and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Cancer Cell 17
(3): 262-272.
16 March 2010
2007
FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf.
Bouchard, C., Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Paulus-Hock, V., Loddenkemper, C., Eilers, M. and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Genes & Development 21
(21): 2775-2787.
1 November 2007
The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.
Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Loddenkemper, C., Rudolph, C., Schildhauer, I., Teichmann, B., Stein, H., Schlegelberger, B., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Blood 110
(8): 2996-3004.
15 October 2007
Cellular senescence and cancer treatment.
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Biochimica et Biophysica Acta - Reviews on Cancer 1775
(1): 5-20.
January 2007
Apoptosis and cancer therapy.
Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
In:
Apoptosis, Cell Signaling, and Human Diseases.
Humana Press, 303-320.
ISBN 978-1-58829-677-1
2007
2006
Oncogene-induced senescence: putting the brakes on tumor development.
Braig, M. and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Cancer Research 66
(6): 2881-2884.
15 March 2006
Mouse models in cancer research.
Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
In:
Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts.
UNSPECIFIED, 671-701.
ISBN 9783527312375
6 February 2006
2005
Oncogene-induced senescence as an initial barrier in lymphoma development.
Braig, M., Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Loddenkemper, C., Rudolph, C., Peters, A.H., Schlegelberger, B., Stein, H., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Jenuwein, T. and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature 436
(7051): 660-665.
4 August 2005
Recurrent chromosomal aberrations in INK4a/ARF defective primary lymphomas predict drug responses in vivo.
Helmrich, A., Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, O'Brien, P., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Lowe, S.W., Schroeck, E. and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Oncogene 24
: 4174-4182.
1 January 2005
2004
Extramedullary manifestation of a donor-derived acute myeloid leukemia in a liver transplant patient.
Subklewe, M., Nagy, M., Schoch, C., Jenisch, S., Siebert, R., Gesk, S., Neuhaus, P., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Schmidt, C.A.
Leukemia 18
(12): 2050-2053.
7 October 2004
Extracorporeal photopheresis in graft-versus-host disease: ultraviolet radiation mediates T cell senescence in vivo.
Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931, Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Transplantation 78
(3): 484-485.
15 August 2004
Cellular senescence in cancer treatment: friend or foe?
Kahlem, P., Doerken, B. ORCID: https://orcid.org/0000-0001-7991-3643 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Journal of Clinical Investigation 113
(2): 169-174.
January 2004
2003
Inter and intraobserver variability in DePalma's classification of shoulder calcific tendinitis.
Maier, M., Maier-Bosse, T., Schulz, C.U., Steinborn, M., Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226, Kleen, M. and Staebler, A.
Journal of Rheumatology 30
(5): 1029-1031.
May 2003
Senescence apoptosis and therapy - cutting the lifelines of cancer.
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature Reviews Cancer 3
(4): 286-295.
April 2003
Chemotherapy response and resistance.
Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Current Opinion in Genetics & Development 13
(1): 90-96.
February 2003
2002
Apoptosis and chemoresistance in transgenic cancer models.
Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226 and Lowe, S.W.
Journal of Molecular Medicine 80
(3): 137-146.
March 2002
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