Browse by Research Team

2024

Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response.
Lafranchi, L., Spinner, A., Hornisch, M., Schlesinger, D., Luzon, C.N., Brinkenstråhle, L., Shao, R., Piazza, I. and Elsässer, S.J.
bioRxiv : 2024.12.08.627409. 9 December 2024

Comparison of Xrn1 and Rat1 5′ → 3′ exoribonucleases in budding yeast supports the specific role of Xrn1 in cotranslational mRNA decay.
Pérez-Ortín, J.E., Jordán-Pla, A., Zhang, Y., Moreno-García, J., Bassot, C., Barba-Aliaga, M., de Campos-Mata, L., Choder, M., Díez, J., Piazza, I., Pelechano, V. and García-Martínez, J.
Yeast 41 (7): 458-472. July 2024

2023

The potential of cross-linking mass spectrometry in the development of protein-protein interaction modulators.
Ruwolt, M., Piazza, I. and Liu, F.
Current Opinion in Structural Biology 82 : 102648. October 2023

Metabolite interactions in the bacterial Calvin cycle and implications for flux regulation.
Sporre, E., Karlsen, J., Schriever, K., Asplund-Samuelsson, J., Janasch, M., Strandberg, L., Karlsson, A., Kotol, D., Zeckey, L., Piazza, I., Syrén, P.O., Edfors, F. and Hudson, E.P.
Communications Biology 6 (1): 947. 18 September 2023

Proteome-wide structural changes measured with limited proteolysis-mass spectrometry: an advanced protocol for high-throughput applications.
Malinovska, L., Cappelletti, V., Kohler, D., Piazza, I., Tsai, T.H., Pepelnjak, M., Stalder, P., Dörig, C., Sesterhenn, F., Elsässer, F., Kralickova, L., Beaton, N., Reiter, L., de Souza, N., Vitek, O. and Picotti, P.
Nature Protocols 18 : 659-682. 16 March 2023

Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation.
Li, B., Zeis, P., Zhang, Y., Alekseenko, A., Fürst, E., Sanchez, Y.P., Lin, G., Tekkedil, M.M., Piazza, I., Steinmetz, L.M. and Pelechano, V.
Nature Communications 14 (1): 910. 17 February 2023

2021

Reversible amyloids of pyruvate kinase couple cell metabolism and stress granule disassembly.
Cereghetti, G., Wilson-Zbinden, C., Kissling, V.M., Diether, M., Arm, A., Yoo, H., Piazza, I., Saad, S., Picotti, P., Drummond, D.A., Sauer, U., Dechant, R. and Peter, M.
Nature Cell Biology 23 (10): 1085-1094. October 2021

Identifying cell-type-specific metabolic signatures using transcriptome and proteome analyses.
Gebert, N., Rahman, S., Lewis, C.A., Ori, A. and Cheng, C.W.
Current Protocols 1 (9): e245. 28 September 2021

The rise of proteome-wide biophysics.
Mateus, A., Savitski, M.M. and Piazza, I.
Molecular Systems Biology 17 (7): e10442. July 2021

Use of cement suspension as an alternative matrix material for textile-reinforced concrete.
Fürst, R., Fürst, E., Vlach, T., Řepka, J., Pokorný, M. and Mózer, V.
Materials 14 (9): 2127. 1 May 2021

Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ.
Cappelletti, V., Hauser, T., Piazza, I., Pepelnjak, M., Malinovska, L., Fuhrer, T., Li, Y., Dörig, C., Boersema, P., Gillet, L., Grossbach, J., Dugourd, A., Saez-Rodriguez, J., Beyer, A., Zamboni, N., Caflisch, A., de Souza, N. and Picotti, P.
Cell 184 (2): 545-559. 21 January 2021

2020

A machine learning-based chemoproteomic approach to identify drug targets and binding sites in complex proteomes.
Piazza, I., Beaton, N., Bruderer, R., Knobloch, T., Barbisan, C., Chandat, L., Sudau, A., Siepe, I., Rinner, O., de Souza, N., Picotti, P. and Reiter, L.
Nature Communications 11 (1): 4200. 21 August 2020

Comparative analysis of the intracellular responses to disease-related aggregation-prone proteins.
Melnik, A., Cappelletti, V., Vaggi, F., Piazza, I., Tognetti, M., Schwarz, C., Cereghetti, G., Ahmed, M.A., Soste, M., Matlack, K., de Souza, N., Csikasz-Nagy, A. and Picotti, P.
Journal of Proteomics 225 : 103862. 15 August 2020

2019

LiP-Quant, an automated chemoproteomic approach to identify drug targets in complex proteomes.
Piazza, I., Beaton, N., Bruderer, R., Knobloch, T., Barbisan, C., Siepe, I., Rinner, O., de Souza, N., Picotti, P. and Reiter, L.
bioRxiv : 860072. 1 December 2019

Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.
Wei, W., Hennig, B.P., Wang, J., Zhang, Y., Piazza, I., Pareja Sanchez, Y., Chabbert, C.D., Adjalley, S.H., Steinmetz, L.M. and Pelechano, V.
Genome Research 29 (12): 1974-1984. December 2019

Network Rewiring of Homologous Recombination Enzymes during Mitotic Proliferation and Meiosis.
Wild, P., Susperregui, A., Piazza, I., Dörig, C., Oke, A., Arter, M., Yamaguchi, M., Hilditch, A.T., Vuina, K., Chan, K.C., Gromova, T., Haber, J.E., Fung, J.C., Picotti, P. and Matos, J.
Molecular Cell 75 (4): 859-874. 22 August 2019

2018

High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds.
Zampieri, M., Szappanos, B., Buchieri, M.V., Trauner, A., Piazza, I., Picotti, P., Gagneux, S., Borrell, S., Gicquel, B., Lelievre, J., Papp, B. and Sauer, U.
Science Translational Medicine 10 (429): eaal3973. 21 February 2018

A map of protein-metabolite interactions reveals principles of chemical communication.
Piazza, I., Kochanowski, K., Cappelletti, V., Fuhrer, T., Noor, E., Sauer, U. and Picotti, P.
Cell 172 (1-2): 358-372. 11 January 2018

2017

Measuring protein structural changes on a proteome-wide scale using limited proteolysis-coupled mass spectrometry.
Schopper, S., Kahraman, A., Leuenberger, P., Feng, Y., Piazza, I., Müller, O., Boersema, P.J. and Picotti, P.
Nature Protocols 12 (11): 2391-2410. November 2017

2014

Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits.
Piazza, I., Rutkowska, A., Ori, A., Walczak, M., Metz, J., Pelechano, V., Beck, M. and Haering, C.H.
Nature Structural & Molecular Biology 21 (6): 560-568. June 2014

2013

Condensin: crafting the chromosome landscape.
Piazza, I., Haering, C.H. and Rutkowska, A.
Chromosoma 122 (3): 175-190. June 2013