Browse by Research Team

2019

Self-organizing neuruloids model developmental aspects of Huntington's disease in the ectodermal compartment.
Haremaki, T. and Metzger, J.J. and Rito, T. and Ozair, M.Z. and Etoc, F. and Brivanlou, A.H.
Nature Biotechnology 37 (10): 1198-1208. October 2019

A 3D model of a human epiblast reveals BMP4-driven symmetry breaking.
Simunovic, M. and Metzger, J.J. and Etoc, F. and Yoney, A. and Ruzo, A. and Martyn, I. and Croft, G. and You, D.S. and Brivanlou, A.H. and Siggia, E.D.
Nature Cell Biology 21 (7): 900-910. July 2019

2018

WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids.
Yoney, A. and Etoc, F. and Ruzo, A. and Carroll, T. and Metzger, J.J. and Martyn, I. and Li, S. and Kirst, C. and Siggia, E.D. and Brivanlou, A.H.
eLife 7 : e3827. 13 November 2018

Synthetic embryology: controlling geometry to model early mammalian development.
Metzger, J.J. and Simunovic, M. and Brivanlou, A.H.
Current Opinion in Genetics & Development 52 : 86-91. October 2018

Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning.
Morgani, S.M. and Metzger, J.J. and Nichols, J. and Siggia, E.D. and Hadjantonakis, A.K.
eLife 7 : e32839. 7 February 2018

Chromosomal instability during neurogenesis in Huntington's disease.
Ruzo, A. and Croft, G.F. and Metzger, J.J. and Galgoczi, S. and Gerber, L.J. and Pellegrini, C. and Wang, H. and Fenner, M. and Tse, S. and Marks, A. and Nchako, C. and Brivanlou, A.H.
Development 145 (2) January 2018

2017

A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use.
Gleicher, N. and Metzger, J. and Croft, G. and Kushnir, V.A. and Albertini, D.F. and Barad, D.H.
Reproductive Biology and Endocrinology 15 (1): 33. 27 April 2017

Channeling of branched flow in weakly scattering anisotropic media.
Degueldre, H. and Metzger, J.J. and Schultheis, E. and Fleischmann, R.
Physical Review Letters 118 (2): 024301. 13 January 2017

2016

A balance between secreted inhibitors and edge sensing controls gastruloid self-organization.
Etoc, F. and Metzger, J. and Ruzo, A. and Kirst, C. and Yoney, A. and Ozair, M.Z. and Brivanlou, A.H. and Siggia, E.D.
Developmental Cell 39 (3): 302-315. 7 November 2016

Self-organization of human embryonic stem cells on micropatterns.
Deglincerti, A. and Etoc, F. and Guerra, M.C. and Martyn, I. and Metzger, J. and Ruzo, A. and Simunovic, M. and Yoney, A. and Brivanlou, A.H. and Siggia, E. and Warmflash, A.
Nature Protocols 11 (11): 2223-2232. November 2016

Non-equilibrium steady states of stochastic processes with intermittent resetting.
Eule, S. and Metzger, J.J.
New Journal of Physics 18 (3): 033006. March 2016

Random focusing of tsunami waves.
Degueldre, H. and Metzger, J.J. and Geisel, T. and Fleischmann, R.
Nature Physics 12 (3): 259-262. March 2016

2014

Statistics of extreme waves in random media.
Metzger, J.J. and Fleischmann, R. and Geisel, T.
Physical Review Letters 112 (20): 203903. 23 May 2014

2013

Experimental observation of a fundamental length scale of waves in random media.
Barkhofen, S. and Metzger, J.J. and Fleischmann, R. and Kuhl, U. and Stöckmann, H.J.
Physical Review Letters 111 (18): 183902. 1 November 2013

Distribution of the fittest individuals and the rate of Muller's ratchet in a model with overlapping generations.
Metzger, J.J. and Eule, S.
PLoS Computational Biology 9 (11): e1003303. November 2013

Intensity fluctuations of waves in random media: what is the semiclassical limit?
Metzger, J.J. and Fleischmann, R. and Geisel, T.
Physical Review Letters 111 (1): 013901. 5 July 2013

2012

How branching can change the conductance of ballistic semiconductor devices.
Maryenko, D. and Ospald, F. and von Klitzing, K. and Smet, J.H. and Metzger, J.J. and Fleischmann, R. and Geisel, T. and Umansky, V.
Physical Review B 85 (19): 195329. 31 May 2012

Random caustics and intensity fluctuations in weakly disordered media.
Fleischmann, R. and Metzger, J. and Geisel, T.
In: Frontiers in Optics 2012/Laser Science XXVIII, 14-18 Oct 2012, Rochester, NY, USA. 2012

2010

Universal statistics of branched flows.
Metzger, J.J. and Fleischmann, R. and Geisel, T.
Physical Review Letters 105 (2): 020601. 9 July 2010