Browse by Research Team

Article

Genome-wide analysis of barrett's adenocarcinoma. a first step towards identifying patients at risk and developing therapeutic paths.
Dai, Y., Wang, Q., Gonzalez Lopez, A., Anders, M., Malfertheiner, P., Vieth, M. and Kemmner, W.
Translational Oncology 11 (1): 116-124. February 2018

C/EBPβ regulates homeostatic and oncogenic gastric cell proliferation.
Regalo, G., Förster, S., Resende, C., Bauer, B., Fleige, B., Kemmner, W., Schlag, P.M., Meyer, T.F., Machado, J.C. and Leutz, A.
Journal of Molecular Medicine 94 (12): 1385-1395. December 2016

Structure-activity relationship study of dendritic polyglycerolamines for efficient siRNA transfection.
Mehrabadi, F.S., Hirsch, O., Zeisig, R., Posocco, P., Laurini, E., Pricl, S., Haag, R., Kemmner, W. and Calderon, M.
RSC Advances 5 (96): 78760-78770. 8 September 2015

High MACC1 expression in combination with mutated KRAS G13 indicates poor survival of colorectal cancer patients.
Ilm, K., Kemmner, W., Osterland, M., Burock, S., Koch, G., Herrmann, P., Schlag, P.M. and Stein, U.
Molecular Cancer 14 (1): 38. 14 February 2015

Concerted down-regulation of immune-system related genes predicts metastasis in colorectal carcinoma.
Fehlker, M., Huska, M.R., Joens, T., Andrade-Navarro, M.A. and Kemmner, W.
BMC Cancer 14 (1): 64. 5 February 2014

Wdr66 is a novel marker for risk stratification and involved in epithelial-mesenchymal transition of esophageal squamous cell carcinoma.
Wang, Q., Ma, C. and Kemmner, W.
BMC Cancer 13 (1): 137. 21 March 2013

Microarray meta-analysis defines global angiogenesis-related gene expression signatures in human carcinomas.
Anders, M., Fehlker, M., Wang, Q., Wissmann, C., Pilarsky, C., Kemmner, W. and Hoecker, M.
Molecular Carcinogenesis 52 (1): 29-38. January 2013

In-vivo tumor imaging using a novel RNAi-based detection mechanism.
Wan, K., Ebert, B., Voigt, J., Wang, Q., Dai, Y., Haag, R. and Kemmner, W.
Nanomedicine 8 (4): 393-398. May 2012

Loss of UDP-N-acetylglucosamine 2-epimerase/ N-acetylmannosamine kinase (GNE) induces apoptotic processes in pancreatic carcinoma cells.
Kemmner, W., Kessel, P., Sanchez-Ruderisch, H., Moeller, H., Hinderlich, S., Schlag, P.M. and Detjen, K.
FASEB Journal 26 (2): 938-946. February 2012

Latent transforming growth factor binding protein 4 (LTBP4) is downregulated in mouse and human DCIS and mammary carcinomas.
Kretschmer, C., Conradi, A., Kemmner, W. and Sterner-Kock, A.
Cellular Oncology 34 (5): 419-434. 6 October 2011

THBS4, a novel stromal molecule of diffuse-type gastric adenocarcinomas, identified by transcriptome-wide expression profiling.
Foerster, S., Gretschel, S., Joens, T., Yashiro, M. and Kemmner, W.
Modern Pathology 24 (10): 1390-1403. October 2011

Integrated microfluidic platform for the electrochemical detection of breast cancer markers in patient serum samples.
Fragoso, A., Latta, D., Laboria, N., von Germar, F., Hansen-Hagge, T.E., Kemmner, W., Gaertner, C., Klemm, R., Drese, K.S. and O'Sullivan, C.K.
Lab on a Chip 11 (4): 625-631. 21 February 2011

Identification of early molecular markers for breast cancer.
Kretschmer, C., Sterner-Kock, A., Siedentopf, F., Schoenegg, W., Schlag, P.M. and Kemmner, W.
Molecular Cancer 10 (1): 15. 11 February 2011

Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.
Juerchott, K., Kuban, R.J., Krech, T., Blüthgen, N., Stein, U., Walther, W., Friese, C., Kielbasa, S.M., Ungethuem, U., Lund, P., Knoesel, T., Kemmner, W., Morkel, M., Fritzmann, J., Schlag, P.M., Birchmeier, W., Krueger, T., Sperling, S., Sers, C., Royer, H.D., Herzel, H. and Schaefer, R.
PLoS Genetics 6 (12): e1001231. 2 December 2010

Amperometric immunosensor for carcinoembryonic antigen in colon cancer samples based on monolayers of dendritic bipodal scaffolds.
Laboria, N., Fragoso, A., Kemmner, W., Latta, D., Nilsson, O., Luz Botero, M., Drese, K. and O'Sullivan, C.K.
Analytical Chemistry 82 (5): 1712-1719. 1 March 2010

HIF-1alpha determines the metastatic potential of gastric cancer cells.
Rohwer, N., Lobitz, S., Daskalow, K., Joens, T., Vieth, M., Schlag, P.M., Kemmner, W., Wiedenmann, B., Cramer, T. and Hoecker, M.
British Journal of Cancer 100 (5): 772-781. 10 March 2009

Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression.
Anders, M., Vieth, M., Roecken, C., Ebert, M., Pross, M., Gretschel, S., Schlag, P.M., Wiedenmann, B., Kemmner, W. and Hoecker, M.
British Journal of Cancer 100 (2): 352-359. 27 January 2009

Efficiency of adjuvant active specific immunization with Newcastle disease virus modified tumor cells in colorectal cancer patients following resection of liver metastases: results of a prospective randomized trial.
Schulze, T., Kemmner, W., Weitz, J., Wernecke, K.D., Schirrmacher, V. and Schlag, P.M.
Cancer Immunology Immunotherapy 58 (1): 61-69. January 2009

The location of small tumor deposits in the SLN predicts Non-SLN macrometastases in breast cancer patients.
Li, J., Haensch, W., Rudas, M., Kemmner, W., Warnick, P., Fischer, J., Gnant, M., Schlag, P.M. and Bembenek, A.
European Journal of Surgical Oncology 34 (8): 857-862. August 2008

REG1A expression is a prognostic marker in colorectal cancer and associated with peritoneal carcinomatosis.
Astrosini, C., Roeefzaad, C., Dai, Y.Y., Dieckgraefe, B.K., Joens, T. and Kemmner, W.
International Journal of Cancer 123 (2): 409-413. 15 July 2008

Markers of tumour angiogenesis and tumour cells in bone marrow in gastric cancer patients.
Gretschel, S., Astrosini, C.h., Vieth, M., Joens, T., Tomov, T., Hoecker, M., Schlag, P.M. and Kemmner, W.
European Journal of Surgical Oncology 34 (6): 642-647. June 2008

Presence of mature DC-Lamp(+) dendritic cells in sentinel and non-sentinel lymph nodes of breast cancer patients.
Bembenek, A., Li, J., Loddenkemper, C., Kemmner, W., Stein, H., Wernecke, K.D. and Schlag, P.M.
European Journal of Surgical Oncology 34 (5): 514-518. May 2008

Silencing of human ferrochelatase causes abundant protoporphyrin-IX accumulation in colon cancer.
Kemmner, W., Wan, K., Ruttinger, S., Ebert, B., Macdonald, R., Klamm, U. and Moesta, K.T.
FASEB Journal 22 (2): 500-509. February 2008

H-REV107-1 stimulates growth in non-small cell lung carcinomas via the activation of mitogenic signaling.
Nazarenko, I., Kristiansen, G., Fonfara, S., Guenther, R., Gieseler, C., Kemmner, W., Schaefer, R., Petersen, I. and Sers, C.
American Journal of Pathology 169 (4): 1427-1439. October 2006

Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression.
Pospisil, H., Herrmann, A., Butherus, K., Pirson, S., Reich, J.G. and Kemmner, W.
BMC Genomics 7 : 148. 13 June 2006

[Effect of cell surface sialic acid and their linkages on adhesion of mammary carcinoma cells].
Wang, X.Y., Lin, S.Q., Li, J.W., Kemmner, W. and Ding, Y.Q.
Journal of Southern Medical University 26 : 742-746. June 2006

Vascular endothelial growth factor-D and its receptor VEGFR-3: Two novel independent prognostic markers in gastric adenocarcinoma.
Juettner, S., Wissmann, C., Joens, T., Vieth, M., Hertel, J., Gretschel, S., Schlag, P.M., Kemmner, W. and Hoecker, M.
Journal of Clinical Oncology 24 (2): 228-240. 10 January 2006

Der Weg zum diagnostischen "Tool" - Entwicklung eines Mikroarrays zur Prognose und Therapie-Praediktion von Darmkrebs [The pathway to diagnostic tool - Development of a microarray for the prognosis and therapy prediction of intestinal cancer].
Kloska, S., Eickhoff, H. and Kemmner, W.
Biospektrum 11 (1): 572-573. 2005

Helicobacter pylori stimulates host vascular endothelial growth factor-A (vegf-A) gene expression via MEK/ERK-dependent activation of Sp1 and Sp3.
Strowski, M.Z., Cramer, T., Schaefer, G., Juettner, S., Walduck, A., Schipani, E., Kemmner, W., Wessler, S., Wunder, C., Weber, M., Meyer, T.F., Wiedenmann, B., Joens, T., Naumann, M. and Hoecker, M.
FASEB Journal 18 (1): 218-220. January 2004

Glycosyltransferase expression in human colonic tissue examined by oligonucleotide arrays.
Kemmner, W., Roefzaad, C., Haensch, W. and Schlag, P.M.
Biochimica et Biophysica Acta - General Subjects 1621 (3): 272-279. 11 June 2003

Oxidative stress regulates vascular endothelial growth factor-A gene transcription through Sp1-and Sp3-dependent activation of two proximal GC-rich promoter elements.
Schaefer, G., Cramer, T., Suske, G., Kemmner, W., Wiedenmann, B. and Hoecker, M.
Journal of Biological Chemistry 278 (10): 8190-8198. 7 March 2003

Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer.
Gretschel, S., Haensch, W., Schlag, P.M. and Kemmner, W.
Oncology 65 (2): 139-145. 2003

Cell surface α2,6-sialylation affects adhesion of breast carcinoma cells.
Lin, S.Q., Kemmner, W., Grigull, S. and Schlag, P.M.
Experimental Cell Research 276 (1): 101-110. 15 May 2002

A rapid bioinformatic method identifies novel genes with direct clinical relevance to colon cancer.
Brett, D., Kemmner, W., Koch, G., Roefzaad, C., Gross, S. and Schlag, P.M.
Oncogene 20 (33): 4581-4585. 27 July 2001

Overexpression of sialyltransferase CMP-sialic Acid : Galbeta1,3GalNAc-R alpha6-sialyltransferase is related to poor patient survival in human colorectal carcinomas.
Schneider, F., Kemmner, W., Haensch, W., Franke, G., Gretschel, S., Karsten, U. and Schlag, P.M.
Cancer Research 61 (11): 4605-4611. 1 June 2001

Prognosefaktoren beim Magenkarzinom.
Gretschel, S., Kemmner, W. and Schlag, P.M.
Onkologe 7 (6): 623-631. 2001

Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Petretti, T., Kemmner, W., Schulze, B. and Schlag, P.M.
Gut 46 (3): 359-366. March 2000

Altered mRNA expression of glycosyltransferases in human gastric carcinomas.
Petretti, T., Schulze, B., Schlag, P.M. and Kemmner, W.
Biochimica et Biophysica Acta 1428 : 209-218. 5 August 1999

Preparation and characterization of differently aggregated colorectal carcinoma cell subpopulations from surgical specimens.
Bosch, J., Brossmer, R., Kemmner, W. and Schlag, P.M.
Cancer Detection and Prevention 22 : 319-329. 1 January 1998

Inhibition of Ga1beta1, 4GlcNAc alpha 2,6 sialyltransferase expression by antisense-oligodeoxynucleotides.
Kemmner, W., Hohaus, K. and Schlag, P.M.
FEBS Letters 409 : 347-350. 1 January 1997

Different sialyltransferase activities in human colorectal carcinoma cells from surgical specimens detected by specific glycoprotein and glycolipid accepters.
Kemmner, W., Krueck, D. and Schlag, P.M.
Clinical and Experimental Metastasis 12 : 245-254. 1 January 1994

Alterations in cell surface carbohydrate composition of a human colon carcinoma cell line affect adhesion to extracellular matrix components.
Kemmner, W., Morgenthaler, J. and Brossmer, R.
Biochimie 74 (1): 117-122. 1 January 1992

Homotypic aggregation and terminal glycosylation of cells from dissociated human colorectal tumor tissue.
Kemmner, W., Schlag, P.M., Moeller, P. and Brossmer, R.
Oncology 49 : 63-67. 1 January 1992

Separation of tumor cells from a suspension of dissociated human colorectal carcinoma tissue by means of monoclonal antibody- coated magnetic beads.
Kemmner, W., Moldenhauer, G., Schlag, P.M. and Brossmer, R.
Journal of Immunological Methods 147 : 197-200. 1 January 1992

Book Section

Transcriptomics and cancer risk assessment.
Kemmner, W.
In: Cancer risk evaluation : methods and trends. Wiley-VCH, Weinheim, 195-205. ISBN 9783527327539 27 April 2011

The human transcriptome: implications for the understanding of human disease.
Schaefer, R., Kemmner, W. and Sers, C.
In: Molecular pathology: the molecular basis of human disease. Elsevier, Academic Press, Amsterdam, 123-149. ISBN 978-0-12-374419-7 2009

Molecular imaging of breast cancer in a transgene mouse model [Molekulare Bildgebung des Mammakarzinoms in einem transgenen Mausmodell].
Jakob, J., Perlitz, C., Ebert, B., Klamm, U., Kemmner, W., Haensch, W., Macdonald, R., Licha, K., Schirner, M., Schlag, P.M. and Moesta, K.T.
In: Chirurgisches Forum 2005 : fuer experimentelle und klinische Forschung 122. Kongress der Deutschen Gesellschaft fuer Chirurgie Berlin, 05.04.-08.04.2005. Deutsche Gesellschaft fuer Chirurgie, 34 . Springer, Berlin, 83-85. 2005

Tumorgenese.
Schlag, P.M., Estevez-Schwarz, L., Kemmner, W., Schumacher, K. and Walther, W.
In: Chirurgische Onkologie. Thieme, Stuttgart [u.a.], 2-17. ISBN 3-13-126111-0 1 January 2002

Review

Cardiovascular medications in angiogenesis- how to avoid the sting in the tail.
Ma, C., Wang, Q., Man, Y. and Kemmner, W.
International Journal of Cancer 131 (6): 1249-1259. 15 September 2012

Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells.
Andre, S., Sanchez-Ruderisch, H., Nakagawa, H., Buchholz, M., Kopitz, J., Forberich, P., Kemmner, W., Boeck, C., Deguchi, K., Detjen, K.M., Wiedenmann, B., von Knebel Doeberitz, M., Gress, T.M., Nishimura, S., Rosewicz, S. and Gabius, H.J.
FEBS Journal 274 (13): 3233-3256. July 2007

Minimalresiduale Tumorerkrankung bei gastrointestinalen Karzinomen : Prognoserelevanz und onkologisch-chirurgische Konsequenzen [Minimal residual tumor in gastrointestinal carcinoma: Relevance to prognosis and oncologic surgical consequences].
Gretschel, S., Bembenek, A., Schulze, T., Kemmner, W. and Schlag, P.M.
Chirurg 77 (12): 1104-1117. 1 December 2006

Editorial

Laser microdissection of a colon cancer specimen with subsequent RNA isolation, mRNA amplification and microarray hybridization.
Stoinski-Bungs, E., Seeger, S., Kemmner, W., Scheinert, P. and Krupp, G.
Nature Methods Application Notes : an10-an11. 1 January 2006