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2024

Cortical matrix remodeling as a hallmark of relapsing-remitting neuroinflammation in MR elastography and quantitative MRI.
Silva, R.V. and Morr, A.S. and Herthum, H. and Koch, S.P. and Mueller, S. and Batzdorf, C.S. and Bertalan, G. and Meyer, T. and Tzschätzsch, H. and Kühl, A.A. and Boehm-Sturm, P. and Braun, J. and Scheel, M. and Paul, F. and Infante-Duarte, C. and Sack, I.
Acta Neuropathologica 147 (1): 8. 4 January 2024

2023

Investigating the mitoprotective effects of S1P receptor modulators ex vivo using a novel semi-automated live imaging set-up.
Ludwig, R. and Malla, B. and Höhrhan, M. and Infante-Duarte, C. and Anderhalten, L.
International Journal of Molecular Sciences 25 (1): 261. 23 December 2023

Brain inflammation induces alterations in glycosaminoglycan metabolism and subsequent changes in CS-4S and hyaluronic acid.
Silva, R.V. and Biskup, K. and Zabala-Jouvin, J.K. and Batzdorf, C.S. and Stellmach, C. and Morr, A.S. and Sack, I. and Ludwig, A. and Blanchard, V. and Infante-Duarte, C.
International Journal of Biological Macromolecules 230 : 123214. March 2023

2022

Mechanical properties of murine hippocampal subregions investigated by atomic force microscopy and in vivo magnetic resonance elastography.
Morr, A.S. and Nowicki, M. and Bertalan, G. and Silva, R.V. and Infante Duarte, C. and Koch, S.P. and Boehm-Sturm, P. and Krügel, U. and Braun, J. and Steiner, B. and Käs, J.A. and Fuhs, T. and Sack, I.
Scientific Reports 12 (1): 16723. 6 October 2022

Different impact of gadopentetate and gadobutrol on inflammation-promoted retention and toxicity of gadolinium within the mouse brain.
Anderhalten, L. and Silva, R.V. and Morr, A. and Wang, S. and Smorodchenko, A. and Saatz, J. and Traub, H. and Mueller, S. and Boehm-Sturm, P. and Rodriguez-Sillke, Y. and Kunkel, D. and Hahndorf, J. and Paul, F. and Taupitz, M. and Sack, I. and Infante-Duarte, C.
Investigative Radiology 57 (10): 677-688. 1 October 2022

Impaired response of blood neutrophils to cell-death stimulus differentiates AQP4-IgG-seropositive NMOSD from MOGAD.
Schroeder-Castagno, M. and Del Rio-Serrato, A. and Wilhelm, A. and Romero-Suárez, S. and Schindler, P. and Alvarez-González, C. and Duchow, A.S. and Bellmann-Strobl, J. and Ruprecht, K. and Hastermann, M. and Grütz, G. and Wildemann, B. and Jarius, S. and Schmitz-Hübsch, T. and Paul, F. and Infante-Duarte, C.
Journal of Neuroinflammation 19 (1): 239. 1 October 2022

Fibrin-targeting molecular MRI in inflammatory CNS disorders.
Lohmeier, J. and Silva, R.V. and Tietze, A. and Taupitz, M. and Kaneko, T. and Prüss, H. and Paul, F. and Infante-Duarte, C. and Hamm, B. and Caravan, P. and Makowski, M.R.
European Journal of Nuclear Medicine and Molecular Imaging 49 (11): 3692–3704. September 2022

Alterations of NK cell phenotype during pregnancy in multiple sclerosis.
Wisgalla, A. and Ramien, C. and Streitz, M. and Schlickeiser, S. and Lupu, A.R. and Diemert, A. and Tolosa, E. and Arck, P.C. and Bellmann-Strobl, J. and Siebert, N. and Heesen, C. and Paul, F. and Friese, M.A. and Infante-Duarte, C. and Gold, S.M.
Frontiers in Immunology 13 : 907994. 4 July 2022

Preventing axonal sodium overload or mitochondrial calcium uptake protects axonal mitochondria from oxidative stress-induced alterations.
Ulshöfer, R. and Bros, H. and Hauser, A.E. and Niesner, R.A. and Paul, F. and Malla, B. and Infante-Duarte, C.
Oxidative Medicine and Cellular Longevity 2022 : 6125711. 24 May 2022

Imaging and analysis of neuronal mitochondria in murine acute brain slices.
Malla, B. and Hauser, A. and Niesner, R. and Infante-Duarte, C.
Journal of Neuroscience Methods 372 : 109558. 15 April 2022

Sexual dimorphism in extracellular matrix composition and viscoelasticity of the healthy and inflamed mouse brain.
Batzdorf, C.S. and Morr, A.S. and Bertalan, G. and Sack, I. and Silva, R.V. and Infante-Duarte, C.
Biology 11 (2): 230. 31 January 2022

Teriflunomide preserves neuronal activity and protects mitochondria in brain slices exposed to oxidative stress.
Malla, B. and Liotta, A. and Bros, H. and Ulshöfer, R. and Paul, F. and Hauser, A.E. and Niesner, R. and Infante-Duarte, C.
International Journal of Molecular Sciences 23 (3): 1538. 28 January 2022

2021

Knock-in mice expressing a 15-lipoxygenating Alox5 mutant respond differently to experimental inflammation than reported mice.
Marbach-Breitrück, E. and Rohwer, N. and Infante-Duarte, C. and Romero-Suarez, S. and Labuz, D. and Machelska, H. and Kutzner, L. and Schebb, N.H. and Rothe, M. and Reddanna, P. and Weylandt, K.H. and Wieler, L.H and Heydeck, D. and Kuhn, H.
Metabolites 11 (10): 698. 12 October 2021

Contribution of tissue inflammation and blood-brain barrier disruption to brain softening in a mouse model of multiple sclerosis.
Silva, R.V. and Morr, A.S. and Mueller, S. and Koch, S.P. and Boehm-Sturm, P. and Rodriguez-Sillke, Y. and Kunkel, D. and Tzschätzsch, H. and Kühl, A.A. and Schnorr, J. and Taupitz, M. and Sack, I. and Infante-Duarte, C.
Frontiers in Neuroscience 15 : 701308. August 2021

Fingolimod therapy in multiple sclerosis leads to the enrichment of a subpopulation of aged NK cells.
Schwichtenberg, S.C. and Wisgalla, A. and Schroeder-Castagno, M. and Alvarez-González, C. and Schlickeiser, S. and Siebert, N. and Bellmann-Strobl, J. and Wernecke, K.D. and Paul, F. and Dörr, J. and Infante-Duarte, C.
Neurotherapeutics 18 (3): 1783-1797. July 2021

Epigallocatechin gallate in relapsing-remitting multiple sclerosis: a randomized, placebo-controlled trial.
Bellmann-Strobl, J. and Paul, F. and Wuerfel, J. and Dörr, J. and Infante-Duarte, C. and Heidrich, E. and Körtgen, B. and Brandt, A. and Pfüller, C. and Radbruch, H. and Rust, R. and Siffrin, V. and Aktas, O. and Heesen, C. and Faiss, J. and Hoffmann, F. and Lorenz, M. and Zimmermann, B. and Groppa, S. and Wernecke, K.D. and Zipp, F.
Neurology Neuroimmunology & Neuroinflammation 8 (3): e981. May 2021

Inebilizumab in AQP4-Ab-positive neuromyelitis optica spectrum disorder.
Siebert, N. and Duchow, A. and Paul, F. and Infante-Duarte, C. and Bellmann-Strobl, J.
Drugs of Today 57 (5): 321-336. May 2021

2020

Transient enlargement of brain ventricles during relapsing-remitting multiple sclerosis and experimental autoimmune encephalomyelitis.
Millward, J.M. and Delgado, P.R. and Smorodchenko, A. and Boehmert, L. and Periquito, J. and Reimann, H.M. and Prinz, C. and Els, A. and Scheel, M. and Bellmann-Strobl, J. and Waiczies, H. and Wuerfel, J. and Infante-Duarte, C. and Chien, C. and Kuchling, J. and Pohlmann, A. and Zipp, F. and Paul, F. and Niendorf, T. and Waiczies, S.
JCI Insight 5 (21): e140040. 5 November 2020

Effect of vitamin D supplementation on N-glycan branching and cellular immunophenotypes in MS.
Bäcker-Koduah, P. and Infante-Duarte, C. and Ivaldi, F. and Uccelli, A. and Bellmann-Strobl, J. and Wernecke, K.D. and Sy, M. and Demetriou, M. and Dörr, J. and Paul, F. and Brandt, A.U.
Annals of Clinical and Translational Neurology 7 (9): 1628-1641. September 2020

MR elastography-based assessment of matrix remodeling at lesion sites associated with clinical severity in a model of multiple sclerosis.
Wang, S. and Millward, J.M. and Hanke-Vela, L. and Malla, B. and Pilch, K. and Gil-Infante, A. and Waiczies, S. and Mueller, S. and Boehm-Sturm, P. and Guo, J. and Sack, I. and Infante-Duarte, C.
Frontiers in Neurology 10 : 1382. 13 January 2020

Teriflunomide preserves peripheral nerve mitochondria from oxidative stress-mediated alterations.
Malla, B. and Cotten, S. and Ulshoefer, R. and Paul, F. and Hauser, A.E. and Niesner, R. and Bros, H. and Infante-Duarte, C.
Therapeutic Advances in Chronic Disease 11 : 1-14. 2020

2019

Brain maturation is associated with increasing tissue stiffness and decreasing tissue fluidity.
Guo, J. and Bertalan, G. and Meierhofer, D. and Klein, C. and Schreyer, S. and Steiner, B. and Wang, S. and Vieira da Silva, R. and Infante-Duarte, C. and Koch, S. and Boehm-Sturm, P. and Braun, J. and Sack, I.
Acta Biomaterialia 99 : 433-442. November 2019

The central nervous system contains ILC1s that differ from NK cells in the response to inflammation.
Romero-Suárez, S. and Del Rio Serrato, A. and Bueno, R.J. and Brunotte-Strecker, D. and Stehle, C. and Figueiredo, C.A. and Hertwig, L. and Dunay, I.R. and Romagnani, C. and Infante-Duarte, C.
Frontiers in Immunology 10 : 2337. 10 October 2019

Increased retention of gadolinium in the inflamed brain after repeated administration of gadopentetate dimeglumine: a proof-of-concept study in mice combining ICP-MS and micro- and nano-SR-XRF.
Wang, S. and Hesse, B. and Roman, M. and Stier, D. and Castillo-Michel, H. and Cotte, M. and Suuronen, J.P. and Lagrange, A. and Radbruch, H. and Paul, F. and Taupitz, M. and Schellenberger, E. and Sack, I. and Infante-Duarte, C.
Investigative Radiology 54 (10): 617-626. October 2019

Application of europium-doped very small iron oxide nanoparticles to visualize neuroinflammation with MRI and fluorescence microscopy.
Millward, J.M. and de Schellenberger, A.A. and Berndt, D. and Hanke-Vela, L. and Schellenberger, E. and Waiczies, S. and Taupitz, M. and Kobayashi, Y. and Wagner, S. and Infante-Duarte, C.
Neuroscience 403 : 136-144. 1 April 2019

Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis.
Graetz, C. and Gröger, A. and Luessi, F. and Salmen, A. and Zöller, D. and Schultz, J. and Siller, N. and Fleischer, V. and Bellenberg, B. and Berthele, A. and Biberacher, V. and Havla, J. and Hecker, M. and Hohlfeld, R. and Infante-Duarte, C. and Kirschke, J.S. and Kümpfel, T. and Linker, R. and Paul, F. and Pfeuffer, S. and Sämann, P. and Toenges, G. and Weber, F. and Zettl, U.K. and Jahn-Eimermacher, A. and Antony, G. and Groppa, S. and Wiendl, H. and Hemmer, B. and Mühlau, M. and Lukas, C. and Gold, R. and Lill, C.M. and Zipp, F.
Multiple Sclerosis Journal 25 (5): 661-668. 1 April 2019

Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation.
Starossom, S.C. and Campo Garcia, J. and Woelfle, T. and Romero-Suarez, S. and Olah, M. and Watanabe, F. and Cao, L. and Yeste, A. and Tukker, J.J. and Quintana, F.J. and Imitola, J. and Witzel, F. and Schmitz, D. and Morkel, M. and Paul, F. and Infante-Duarte, C. and Khoury, S.J.
Nature Communications 10 (1): 217. 15 January 2019

2017

Synthesis of europium-doped VSOP, customized enhancer solution and improved microscopy fluorescence methodology for unambiguous histological detection.
de Schellenberger, A.A. and Hauptmann, R. and Millward, J.M. and Schellenberger, E. and Kobayashi, Y. and Taupitz, M. and Infante-Duarte, C. and Schnorr, J. and Wagner, S.
Journal of Nanobiotechnology 15 (1): 71. 10 October 2017

CX3CR1 knockout aggravates Coxsackievirus B3-induced myocarditis.
Müller, I. and Pappritz, K. and Savvatis, K. and Puhl, K. and Dong, F. and El-Shafeey, M. and Hamdani, N. and Hamann, I. and Noutsias, M. and Infante-Duarte, C. and Linke, W.A. and Van Linthout, S. and Tschöpe, C.
PLoS ONE 12 (8): e0182643. 11 August 2017

Inflammation-induced brain endothelial activation leads to uptake of electrostatically stabilized iron oxide nanoparticles via sulfated glycosaminoglycans.
Berndt, D. and Millward, J.M. and Schnorr, J. and Taupitz, M. and Stangl, V. and Paul, F. and Wagner, S. and Wuerfel, J.T. and Sack, I. and Ludwig, A. and Infante-Duarte, C.
Nanomedicine: Nanotechnology, Biology and Medicine 13 (4): 1411-1421. May 2017

Alzheimer's disease: elevated pigment epithelium-derived factor in the cerebrospinal fluid is mostly of systemic origin.
Lang, V. and Zille, M. and Infante-Duarte, C. and Jarius, S. and Jahn, H. and Paul, F. and Ruprecht, K. and Pina, A.L.
Journal of the Neurological Sciences 375 : 123-128. 15 April 2017

2016

CX3CR1-dependent recruitment of mature NK cells into the central nervous system contributes to control autoimmune neuroinflammation.
Hertwig, L. and Hamann, I. and Romero-Suarez, S. and Millward, J.M. and Pietrek, R. and Chanvillard, C. and Stuis, H. and Pollok, K. and Ransohoff, R.M. and Cardona, A.E. and Infante-Duarte, C.
European Journal of Immunology 46 (8): 1984-1996. August 2016

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation.
Andlauer, T.F.M. and Buck, D. and Antony, G. and Bayas, A. and Bechmann, L. and Berthele, A. and Chan, A. and Gasperi, C. and Gold, R. and Graetz, C. and Haas, J. and Hecker, M. and Infante-Duarte, C. and Knop, M. and Kümpfel, T. and Limmroth, V. and Linker, R.A. and Loleit, V. and Luessi, F. and Meuth, S.G. and Muehlau, M. and Nischwitz, S. and Paul, F. and Pütz, M. and Ruck, T. and Salmen, A. and Stangel, M. and Stellmann, J.P. and Stuerner, K.H. and Tackenberg, B. and Then Bergh, F. and Tumani, H. and Warnke, C. and Weber, F. and Wiendl, H. and Wildemann, B. and Zettl, U.K. and Ziemann, U. and Zipp, F. and Arloth, J. and Weber, P. and Radivojkov-Blagojevic, M. and Scheinhardt, M.O. and Dankowski, T. and Bettecken, T. and Lichtner, P. and Czamara, D. and Carrillo-Roa, T. and Binder, E.B. and Berger, K. and Bertram, L. and Franke, A. and Gieger, C. and Herms, S. and Homuth, G. and Ising, M. and Jöckel, K.H. and Kacprowski, T. and Kloiber, S. and Laudes, M. and Lieb, W. and Lill, C.M. and Lucae, S. and Meitinger, T. and Moebus, S. and Mueller-Nurasyid, M. and Nöthen, M.M. and Petersmann, A. and Rawal, R. and Schminke, U. and Strauch, K. and Völzke, H. and Waldenberger, M. and Wellmann, J. and Porcu, E. and Mulas, A. and Pitzalis, M. and Sidore, C. and Zara, I. and Cucca, F. and Zoledziewska, M. and Ziegler, A. and Hemmer, B. and Müller-Myhsok, B.
Science Advances 2 (6): e1501678. 17 June 2016

Distinct functionality of neutrophils in multiple sclerosis and neuromyelitis optica.
Hertwig, L. and Pache, F. and Romero-Suarez, S. and Stuerner, K.H. and Borisow, N. and Behrens, J. and Bellmann-Strobl, J. and Seeger, B. and Asselborn, N. and Ruprecht, K. and Millward, J.M. and Infante-Duarte, C. and Paul, F.
Multiple Sclerosis Journal 22 (2): 160-173. February 2016

2015

Successful replication of GWAS hits for multiple sclerosis in 10,000 Germans using the exome array.
Dankowski, T. and Buck, D. and Andlauer, T.F.M. and Antony, G. and Bayas, A. and Bechmann, L. and Berthele, A. and Bettecken, T. and Chan, A. and Franke, A. and Gold, R. and Graetz, C. and Haas, J. and Hecker, M. and Herms, S. and Infante-Duarte, C. and Jöckel, K.H. and Kieseier, B.C. and Knier, B. and Knop, M. and Kümpfel, T. and Lichtner, P. and Lieb, W. and Lill, C.M. and Limmroth, V. and Linker, R.A. and Loleit, V. and Meuth, S.G. and Moebus, S. and Müller-Myhsok, B. and Nischwitz, S. and Nöthen, M.M. and Paul, F. and Puetz, M. and Ruck, T. and Salmen, A. and Stangel, M. and Stellmann, J.P. and Strauch, K. and Stürner, K.H. and Tackenberg, B. and Then Bergh, F. and Tumani, H. and Waldenberger, M. and Weber, F. and Wiendl, H. and Wildemann, B. and Zettl, U.K. and Ziemann, U. and Zipp, F. and Hemmer, B. and Ziegler, A.
Genetic Epidemiology 39 (8): 601-608. December 2015

Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation.
Mossakowski, A.A. and Pohlan, J. and Bremer, D. and Lindquist, R. and Millward, J.M. and Bock, M. and Pollok, K. and Mothes, R. and Viohl, L. and Radbruch, M. and Gerhard, J. and Bellmann-Strobl, J. and Behrens, J. and Infante-Duarte, C. and Mähler, A. and Boschmann, M. and Rinnenthal, J.L. and Füchtemeier, M. and Herz, J. and Pache, F.C. and Bardua, M. and Priller, J. and Hauser, A.E. and Paul, F. and Niesner, R. and Radbruch, H.
Acta Neuropathologica 130 (6): 799-814. December 2015

Assessing mitochondrial movement within neurons: manual versus automated tracking methods.
Bros, H. and Hauser, A. and Paul, F. and Niesner, R. and Infante-Duarte, C.
Traffic 16 (8): 906-917. August 2015

Tissue structure and inflammatory processes shape viscoelastic properties of the mouse brain.
Millward, J.M. and Guo, J. and Berndt, D. and Braun, J. and Sack, I. and Infante-Duarte, C.
NMR in Biomedicine 28 (7): 831-839. July 2015

Treatment of chronic experimental autoimmune encephalomyelitis with epigallocatechin-3-gallate and glatiramer acetate alters expression of heme-oxygenase-1.
Janssen, A. and Fiebiger, S. and Bros, H. and Hertwig, L. and Romero-Suarez, S. and Hamann, I. and Chanvillard, C. and Bellmann-Strobl, J. and Paul, F. and Millward, J.M. and Infante-Duarte, C.
PLoS ONE 10 (6): e0130251. 26 June 2015

An ex vivo model for studying mitochondrial trafficking in neurons.
Bros, H. and Niesner, R. and Infante-Duarte, C.
Methods in Molecular Biology 1264 : 465-472. 2015

2014

Oxidative damage to mitochondria at the nodes of Ranvier precedes axon degeneration in ex vivo transected axons.
Bros, H. and Millward, J.M. and Paul, F. and Niesner, R. and Infante-Duarte, C.
Experimental Neurology 261 (11): 127-135. November 2014

Modulation of dendritic cell immunobiology via inhibition of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase.
Leuenberger, T. and Pfueller, C.F. and Luessi, F. and Bendix, I. and Paterka, M. and Prozorovski, T. and Treue, D. and Luenstedt, S. and Herz, J. and Siffrin, V. and Infante-Duarte, C. and Zipp, F. and Waiczies, S.
PLoS ONE 9 (7): e100871. 11 July 2014

2013

The antioxidant idebenone fails to prevent or attenuate chronic experimental autoimmune encephalomyelitis in the mouse.
Fiebiger, S.M. and Bros, H. and Grobosch, T. and Janssen, A. and Chanvillard, C. and Paul, F. and Dörr, J. and Millward, J.M. and Infante-Duarte, C.
Journal of Neuroimmunology 262 (1-2): 66-71. 15 September 2013

The role of natural killer cells in multiple sclerosis and their therapeutic implications.
Chanvillard, C. and Jacolik, R.F. and Infante-Duarte, C. and Nayak, R.C.
Frontiers in Immunology 4 : 63. 13 March 2013

Iron oxide magnetic nanoparticles highlight early involvement of the choroid plexus in central nervous system inflammation.
Millward, J.M. and Schnorr, J. and Taupitz, M. and Wagner, S. and Wuerfel, J.T. and Infante-Duarte, C.
ASN Neuro 5 (1): e00110. 1 March 2013

Characterization of natural killer cells in paired CSF and blood samples during neuroinflammation.
Hamann, I. and Dörr, J. and Glumm, R. and Chanvillard, C. and Janssen, A. and Millward, J.M. and Paul, F. and Ransohoff, R.M. and Infante-Duarte, C.
Journal of Neuroimmunology 254 (1-2): 165-169. 15 January 2013

2012

Magnetic resonance elastography reveals altered brain viscoelasticity in experimental autoimmune encephalomyelitis.
Riek, K. and Millward, J.M. and Hamann, I. and Mueller, S. and Pfueller, C.F. and Paul, F. and Braun, J. and Infante-Duarte, C. and Sack, I.
NeuroImage: Clinical 1 (1): 81-90. 12 November 2012

Quantification of uncoupling protein 2 reveals its main expression in immune cells and selective up-regulation during T-cell proliferation.
Rupprecht, A. and Braeuer, A.U. and Smorodchenko, A. and Goyn, J. and Hilse, K.E. and Shabalina, I.G. and Infante-Duarte, C. and Pohl, E.E.
PLoS ONE 7 (8): e41406. 3 August 2012

Mitoxantrone induces natural killer cell maturation in patients with secondary progressive multiple sclerosis.
Chanvillard, C. and Millward, J.M. and Lozano, M. and Hamann, I. and Paul, F. and Zipp, F. and Doerr, J. and Infante-Duarte, C.
PLoS ONE 7 (6): e39625. 29 June 2012

Identification of cellular infiltrates during early stages of brain inflammation with magnetic resonance microscopy.
Waiczies, H. and Millward, J.M. and Lepore, S. and Infante-Duarte, C. and Pohlmann, A. and Niendorf, T. and Waiczies, S.
PLoS ONE 7 (3): e32796. 12 March 2012

2011

Neuroprotective effect of combination therapy of glatiramer acetate and epigallocatechin-3-gallate in neuroinflammation.
Herges, K. and Millward, J.M. and Hentschel, N. and Infante-Duarte, C. and Aktas, O. and Zipp, F.
PLoS ONE 6 (10): e25456. 13 October 2011

Arteriogenesis is modulated on bradykinin receptor signaling.
Hillmeister, P. and Gatzke, N. and Duelsner, A. and Bader, M. and Schadock, I. and Hoefer, I. and Hamann, I. and Infante-Duarte, C. and Jung, G. and Troidl, K. and Urban, D. and Stawowy, P. and Frentsch, M. and Li, M. and Nagorka, S. and Wang, H. and Shi, Y. and le Noble, F. and Buschmann, I.
Circulation Research 109 (5): 524-533. 19 August 2011

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Sawcer, S. and Hellenthal, G. and Pirinen, M. and Spencer, C.C. and Patsopoulos, N.A. and Moutsianas, L. and Dilthey, A. and Su, Z. and Freeman, C. and Hunt, S.E. and Edkins, S. and Gray, E. and Booth, D.R. and Potter, S.C. and Goris, A. and Band, G. and Oturai, A.B. and Strange, A. and Saarela, J. and Bellenguez, C. and Fontaine, B. and Gillman, M. and Hemmer, B. and Gwilliam, R. and Zipp, F. and Jayakumar, A. and Martin, R. and Leslie, S. and Hawkins, S. and Giannoulatou, E. and D'alfonso, S. and Blackburn, H. and Boneschi, F.M. and Liddle, J. and Harbo, H.F. and Perez, M.L. and Spurkland, A. and Waller, M.J. and Mycko, M.P. and Ricketts, M. and Comabella, M. and Hammond, N. and Kockum, I. and McCann, O.T. and Ban, M. and Whittaker, P. and Kemppinen, A. and Weston, P. and Hawkins, C. and Widaa, S. and Zajicek, J. and Dronov, S. and Robertson, N. and Bumpstead, S.J. and Barcellos, L.F. and Ravindrarajah, R. and Abraham, R. and Alfredsson, L. and Ardlie, K. and Aubin, C. and Baker, A. and Baker, K. and Baranzini, S.E. and Bergamaschi, L. and Bergamaschi, R. and Bernstein, A. and Berthele, A. and Boggild, M. and Bradfield, J.P. and Brassat, D. and Broadley, S.A. and Buck, D. and Butzkueven, H. and Capra, R. and Carroll, W.M. and Cavalla, P. and Celius, E.G. and Cepok, S. and Chiavacci, R. and Clerget-Darpoux, F. and Clysters, K. and Comi, G. and Cossburn, M. and Cournu-Rebeix, I. and Cox, M.B. and Cozen, W. and Cree, B.A. and Cross, A.H. and Cusi, D. and Daly, M.J. and Davis, E. and de Bakker, P.I. and Debouverie, M. and D'hooghe, M.B. and Dixon, K. and Dobosi, R. and Dubois, B. and Ellinghaus, D. and Elovaara, I. and Esposito, F. and Fontenille, C. and Foote, S. and Franke, A. and Galimberti, D. and Ghezzi, A. and Glessner, J. and Gomez, R. and Gout, O. and Graham, C. and Grant, S.F. and Guerini, F.R. and Hakonarson, H. and Hall, P. and Hamsten, A. and Hartung, H.P. and Heard, R.N. and Heath, S. and Hobart, J. and Hoshi, M. and Infante-Duarte, C. and Ingram, G. and Ingram, W. and Islam, T. and Jagodic, M. and Kabesch, M. and Kermode, A.G. and Kilpatrick, T.J. and Kim, C. and Klopp, N. and Koivisto, K. and Larsson, M. and Lathrop, M. and Lechner-Scott, J.S. and Leone, M.A. and Leppa, V. and Liljedahl, U. and Bomfim, I.L. and Lincoln, R.R. and Link, J. and Liu, J. and Lorentzen, A.R. and Lupoli, S. and Macciardi, F. and Mack, T. and Marriott, M. and Martinelli, V. and Mason, D. and McCauley, J.L. and Mentch, F. and Mero, I.L. and Mihalova, T. and Montalban, X. and Mottershead, J. and Myhr, K.M. and Naldi, P. and Ollier, W. and Page, A. and Palotie, A. and Pelletier, J. and Piccio, L. and Pickersgill, T. and Piehl, F. and Pobywajlo, S. and Quach, H.L. and Ramsay, P.P. and Reunanen, M. and Reynolds, R. and Rioux, J.D. and Rodegher, M. and Roesner, S. and Rubio, J.P. and Ruckert, I.M. and Salvetti, M. and Salvi, E. and Santaniello, A. and Schaefer, C.A. and Schreiber, S. and Schulze, C. and Scott, R.J. and Sellebjerg, F. and Selmaj, K.W. and Sexton, D. and Shen, L. and Simms-Acuna, B. and Skidmore, S. and Sleiman, P.M. and Smestad, C. and Sorensen, P.S. and Sondergaard, H.B. and Stankovich, J. and Strange, R.C. and Sulonen, A.M. and Sundqvist, E. and Syvanen, A.C. and Taddeo, F. and Taylor, B. and Blackwell, J.M. and Tienari, P. and Bramon, E. and Tourbah, A. and Brown, M.A. and Tronczynska, E. and Casas, J.P. and Tubridy, N. and Corvin, A. and Vickery, J. and Jankowski, J. and Villoslada, P. and Markus, H.S. and Wang, K. and Mathew, C.G. and Wason, J. and Palmer, C.N. and Wichmann, H.E. and Plomin, R. and Willoughby, E. and Rautanen, A. and Winkelmann, J. and Wittig, M. and Trembath, R.C. and Yaouanq, J. and Viswanathan, A.C. and Zhang, H. and Wood, N.W. and Zuvich, R. and Deloukas, P. and Langford, C. and Duncanson, A. and Oksenberg, J.R. and Pericak-Vance, M.A. and Haines, J.L. and Olsson, T. and Hillert, J. and Ivinson, A.J. and De Jager, P.L. and Peltonen, L. and Stewart, G.J. and Hafler, D.A. and Hauser, S.L. and McVean, G. and Donnelly, P. and Compston, A.
Nature 476 (7359): 214-219. 10 August 2011

Analyses of phenotypic and functional characteristics of CX3CR1-expressing natural killer cells.
Hamann, I. and Unterwalder, N. and Cardona, A.E. and Meisel, C. and Zipp, F. and Ransohoff, R.M. and Infante-Duarte, C.
Immunology 133 (1): 62-73. May 2011

2010

Gadofluorine M-enhanced MRI shows involvement of circumventricular organs in neuroinflammation.
Wuerfel, E. and Infante-Duarte, C. and Glumm, R. and Wuerfel, J.T.
Journal of Neuroinflammation 7 (1): 70. 18 October 2010

No significant effect of orally administered chemokine receptor 1 antagonist on intercellular adhesion molecule-3 expression in relapsing--remitting multiple sclerosis patients.
Reuss, R. and Schreiber, V. and Klein, A. and Infante-Duarte, C. and Filippi, M. and Pabst, W. and Pohl, C. and Oschmann, P.
Multiple Sclerosis 16 (3): 366-369. March 2010

2009

United Europeans for development of pharmacogenomics in multiple sclerosis network.
Vandenbroeck, K. and Comabella, M. and Tolosa, E. and Goertsches, R. and Brassat, D. and Hintzen, R. and Infante-Duarte, C. and Favorov, A. and Escorza, S. and Palacios, R. and Oksenberg, J.R. and Villoslada, P.
Pharmacogenomics 10 (5): 885-894. May 2009

2008

Therapeutic targeting of chemokine signaling in Multiple Sclerosis.
Hamann, I. and Zipp, F. and Infante-Duarte, C.
Journal of the Neurological Sciences 274 (1-2): 31-38. 15 November 2008

New developments in understanding and treating neuroinflammation.
Infante-Duarte, C. and Waiczies, S. and Wuerfel, J. and Zipp, F.
Journal of Molecular Medicine 86 (9): 975-985. September 2008

2007

CNS-irrelevant T-cells enter the brain, cause blood-brain barrier disruption but no glial pathology.
Smorodchenko, A. and Wuerfel, J. and Pohl, E.E. and Vogt, J. and Tysiak, E. and Glumm, R. and Hendrix, S. and Nitsch, R. and Zipp, F. and Infante-Duarte, C.
European Journal of Neuroscience 26 (6): 1387-1398. September 2007

Neuronal damage in brain inflammation.
Aktas, O. and Ullrich, O. and Infante-Duarte, C. and Nitsch, R. and Zipp, F.
Archives of Neurology 64 (2): 185-189. February 2007

Serum levels of soluble CD95 are not associated with amelioration of multiple sclerosis during pregnancy.
Ehrlich, S. and Haas, J. and Zipp, F. and Infante-Duarte, C.
Journal of the Neurological Sciences 252 (1): 83-87. January 2007

2006

Blockade of chemokine signaling in patients with multiple sclerosis.
Zipp, F. and Hartung, H.P. and Hillert, J. and Schimrigk, S. and Trebst, C. and Stangel, M. and Infante-Duarte, C. and Jakobs, P. and Wolf, C. and Sandbrink, R. and Pohl, C. and Filippi, M.
Neurology 67 (10): 1880-1883. 28 November 2006

2005

Frequency of blood CX3CR1-positive natural killer cells correlates with disease activity in multiple sclerosis patients.
Infante-Duarte, C. and Weber, A. and Kratzschmar, J. and Prozorovski, T. and Pikol, S. and Hamann, I. and Bellmann-Strobl, J. and Aktas, O. and Doerr, J. and Wuerfel, J. and Stuerzebecher, C.S. and Zipp, F.
FASEB Journal 19 (13): 1902-1904. November 2005

Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL.
Aktas, O. and Smorodchenko, A. and Brocke, S. and Infante-Duarte, C. and Schulze Topphoff, U. and Vogt, J. and Prozorovski, T. and Meier, S. and Osmanova, V. and Pohl, E. and Bechmann, I. and Nitsch, R. and Zipp, F.
Neuron 46 (3): 421-432. 5 May 2005

Atorvastatin induces T cell anergy via phosphorylation of ERK1.
Waiczies, S. and Prozorovski, T. and Infante-Duarte, C. and Hahner, A. and Aktas, O. and Ullrich, O. and Zipp, F.
Journal of Immunology 174 (9): 5630-5635. 1 May 2005

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