Browse by Research Team

Article

Yos9p assists in the degradation of certain non-glycosylated proteins from the endoplasmic reticulum.
Jaenicke, L.A., Brendebach, H., Selbach, M. and Hirsch, C.
Molecular Biology of the Cell 22 (16): 2937-2945. August 2011

Usa1 functions as a scaffold of the HRD-ubiquitin ligase.
Horn, S.C., Hanna, J., Hirsch, C., Volkwein, C., Schütz, A., Heinemann, U., Sommer, T. and Jarosch, E.
Molecular Cell 36 (5): 782-793. 11 December 2009

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum.
Clerc, S., Hirsch, C., Oggier, D.M., Deprez, P., Jakob, C., Sommer, T. and Aebi, M.
Journal of Cell Biology 184 (1): 159-172. 12 January 2009

A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.
Gauss, R., Jarosch, E., Sommer, T. and Hirsch, C.
Nature Cell Biology 8 (8): 849-854. August 2006

Review

The ubiquitylation machinery of the endoplasmic reticulum.
Hirsch, C., Gauss, R., Horn, S.C., Neuber, O. and Sommer, T.
Nature 458 (7237): 453-460. 26 March 2009

Coping with stress: cellular relaxation techniques.
Hirsch, C., Gauss, R. and Sommer, T.
Trends in Cell Biology 16 (12): 657-663. December 2006

ERAD: the long road to destruction.
Meusser, B., Hirsch, C., Jarosch, E. and Sommer, T.
Nature Cell Biology 7 (8): 766-772. August 2005

Endoplasmic reticulum-associated protein degradation - one model fits all?
Hirsch, C., Jarosch, E., Sommer, T. and Wolf, D.H.
Biochimica et Biophysica Acta - Molecular Cell Research 1695 (1-3): 215-223. 1 January 2004

Editorial

San1p, checking up on nuclear proteins.
Sommer, T. and Hirsch, C.
Cell 120 (6): 734-736. 1 January 2005