Browse by Research Team

Article

Yos9p assists in the degradation of certain non-glycosylated proteins from the endoplasmic reticulum.
Jaenicke, L.A. and Brendebach, H. and Selbach, M. and Hirsch, C.
Molecular Biology of the Cell 22 (16): 2937-2945. August 2011

Usa1 functions as a scaffold of the HRD-ubiquitin ligase.
Horn, S.C. and Hanna, J. and Hirsch, C. and Volkwein, C. and Schütz, A. and Heinemann, U. and Sommer, T. and Jarosch, E.
Molecular Cell 36 (5): 782-793. 11 December 2009

Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum.
Clerc, S. and Hirsch, C. and Oggier, D.M. and Deprez, P. and Jakob, C. and Sommer, T. and Aebi, M.
Journal of Cell Biology 184 (1): 159-172. 12 January 2009

A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.
Gauss, R. and Jarosch, E. and Sommer, T. and Hirsch, C.
Nature Cell Biology 8 (8): 849-854. August 2006

Review

The ubiquitylation machinery of the endoplasmic reticulum.
Hirsch, C. and Gauss, R. and Horn, S.C. and Neuber, O. and Sommer, T.
Nature 458 (7237): 453-460. 26 March 2009

Coping with stress: cellular relaxation techniques.
Hirsch, C. and Gauss, R. and Sommer, T.
Trends in Cell Biology 16 (12): 657-663. December 2006

ERAD: the long road to destruction.
Meusser, B. and Hirsch, C. and Jarosch, E. and Sommer, T.
Nature Cell Biology 7 (8): 766-772. August 2005

Endoplasmic reticulum-associated protein degradation - one model fits all?
Hirsch, C. and Jarosch, E. and Sommer, T. and Wolf, D.H.
Biochimica et Biophysica Acta - Molecular Cell Research 1695 (1-3): 215-223. 1 January 2004

Editorial

San1p, checking up on nuclear proteins.
Sommer, T. and Hirsch, C.
Cell 120 (6): 734-736. 1 January 2005