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Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds.
Kowalczyk, I. and Lee, C. and Schuster, E. and Hoeren, J. and Trivigno, V. and Riedel, L. and Görne, J. and Wallingford, J.B. and Hammes, A. and Feistel, K.
Development 148 (2): dev195008. 26 January 2021


Identification of novel disease relevant genetic modifiers affecting the SHH pathway in the developing brain.
Mecklenburg, N. and Kowalczyk, I. and Witte, F. and Görne, J. and Laier, A. and Gonschior, H. and Lehmann, M. and Richter, M. and Sporbert, A. and Purfürst, B. and Hübner, N. and Hammes, A.
bioRxiv : 2020.11.03.366302. 3 November 2020

Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds.
Kowalczyk, I. and Lee, C. and Schuster, E. and Hoeren, J. and Trivigno, V. and Riedel, L. and Goerne, J. and Wallingford, J.B. and Hammes-Lewin, A. and Feistel, K.
bioRxiv : 2020.07.15.205252. 16 July 2020


Identification of novel regulators of developmental hematopoiesis using endoglin regulatory elements as molecular probes.
Nasrallah, R. and Fast, E.M. and Solaimani, P. and Knezevic, K. and Eliades, A. and Patel, R. and Thambyrajah, R. and Unnikrishnan, A. and Thoms, J. and Beck, D. and Vink, C.S. and Smith, A. and Wong, J. and Shepherd, M. and Kent, D. and Roychoudhuri, R. and Paul, F. and Klippert, J. and Hammes, A. and Willnow, T. and Göttgens, B. and Dzierzak, E. and Zon, L.I. and Lacaud, G. and Kouskoff, V. and Pimanda, J.E.
Blood 128 (15): 1928-1939. 13 October 2016

Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L. and Czajkowski, M.T. and Barth, C. and Müller, P.M. and McShane, E. and Grunwald, S. and Beaudette, P. and Mecklenburg, N. and Volkmer, R. and Zühlke, K. and Dittmar, G. and Selbach, M. and Hammes, A. and Daumke, O. and Klussmann, E. and Urbé, S. and Rocks, O.
Nature Communications 7 : 12963. 7 October 2016


LRP2 acts as SHH clearance receptor to protect the retinal margin from mitogenic stimuli.
Christ, A. and Christa, A. and Klippert, J. and Eule, J.C. and Bachmann, S. and Wallace, V.A. and Hammes, A. and Willnow, T.E.
Developmental Cell 35 (1): 36-48. 12 October 2015


LRP2 mediates folate uptake in the developing neural tube.
Kur, E. and Mecklenburg, N. and Cabrera, R.M. and Willnow, T.E. and Hammes, A.
Journal of Cell Science 127 (Pt 10): 2261-2268. 15 May 2014


Endocytic receptor-mediated control of morphogen signaling.
Willnow, T.E. and Christ, A. and Hammes, A.
Development 139 (23): 4311-4319. 1 December 2012

LRP2 is an auxiliary SHH receptor required to condition the forebrain ventral midline for inductive signals.
Christ, A. and Christa, A. and Kur, E. and Lioubinski, O. and Bachmann, S. and Willnow, T.E. and Hammes, A.
Developmental Cell 22 (2): 268-278. 14 February 2012


Loss of Lrp2 in zebrafish disrupts pronephric tubular clearance but not forebrain development.
Kur, E. and Christa, A. and Veth, K.N. and Gajera, C.R. and Andrade-Navarro, M.A. and Zhang, J. and Willer, J.R. and Gregg, R.G. and Abdelilah-Seyfried, S. and Bachmann, S. and Link, B.A. and Hammes, A. and Willnow, T.E.
Developmental Dynamics 240 (6): 1567-1577. June 2011


Mutation of megalin leads to urinary loss of selenoprotein P and selenium deficiency in serum, liver, kidneys and brain.
Chiu-Ugalde, J. and Theilig, F. and Behrends, T. and Drebes, J. and Sieland, C. and Subbarayal, P. and Koehrle, J. and Hammes, A. and Schomburg, L. and Schweizer, U.
Biochemical Journal 431 (1): 103-111. 1 October 2010

The soluble intracellular domain of megalin does not affect renal proximal tubular function in vivo.
Christ, A. and Terryn, S. and Schmidt, V. and Christensen, E.I. and Huska, M.R. and Andrade-Navarro, M.A. and Huebner, N. and Devuyst, O. and Hammes, A. and Willnow, T.E.
Kidney International 78 (5): 473-477. September 2010

LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche.
Gajera, C.R. and Emich, H. and Lioubinski, O. and Christ, A. and Beckervordersandforth-Bonk, R. and Yoshikawa, K. and Bachmann, S. and Christensen, E.I. and Goetz, M. and Kempermann, G. and Peterson, A.S. and Willnow, T.E. and Hammes, A.
Journal of Cell Science 123 (Pt 11): 1922-1930. 1 June 2010

Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease.
Joutel, A. and Monet-Lepretre, M. and Gosele, C. and Baron-Menguy, C. and Hammes, A. and Schmidt, S. and Lemaire-Carrette, B. and Domenga, V. and Schedl, A. and Lacombe, P. and Huebner, N.
Journal of Clinical Investigation 120 (2): 433-445. 1 February 2010


Endocytosis of sex steroids: The hypothesis of free hormones revisited.
Willnow, T.E. and Hammes, A. and Nykjaer, A.
Annales d'Endocrinologie 69 (2): 101-102. April 2008


Lipoproteins and their receptors in embryonic development: more than cholesterol clearance.
Willnow, T.E. and Hammes, A. and Eaton, S.
Development 134 (18): 3239-3249. September 2007


Role of endocytosis in cellular uptake of sex steroids.
Hammes, A. and Andreassen, T.K. and Spoelgen, R. and Raila, J. and Huebner, N. and Schulz, H. and Metzger, J. and Schweigert, F.J. and Luppa, P.B. and Nykjaer, A. and Willnow, T.E.
Cell 122 (5): 751-762. 9 September 2005

A splice variant of the Wilms' tumour suppressor Wt1 is required for normal development of the olfactory system.
Wagner, N. and Wagner, K.D. and Hammes, A. and Kirschner, K.M. and Vidal, V.R. and Schedl, A. and Scholz, H.
Development 132 (6): 1327-1336. 1 January 2005

LRP2/megalin is required for patterning of the ventral telencephalon.
Spoelgen, R. and Hammes, A. and Anzenberger, U. and Zechner, D. and Andersen, O.M. and Jerchow, B. and Willnow, T.E.
Development 132 (2): 405-414. 1 January 2005


α-tropomyosin mutations Asp175Asn and Glu180Gly affect cardiac function in transgenic rats in different ways.
Wernicke, D. and Thiel, C. and Duja-Isac, C.M. and Essine, K.V. and Spindler, M. and Nunez, D.J.R. and Plehm, R. and Wessel, N. and Hammes, A. and Edwards, R.J. and Lippoldt, A. and Zacharias, U. and Stroemer, H. and Neubauer, S. and Davies, M.J. and Morano, I. and Thierfelder, L.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 287 (3): R685-R695. 1 September 2004


Transgenic overexpression of the sarcoplasmic reticulum Ca(2+) ATPase improves reticular Ca(2+) handling in normal and diabetic rat hearts.
Vetter, R. and Rehfeld, U. and Reissfelder, C. and Weiss, W. and Wagner, K.D. and Guenther, J. and Hammes, A. and Tschoepe, C. and Dillmann, W. and Paul, M.
FASEB Journal 16 (12): 1657-1659. October 2002

Early gonadal development: exploring Wt1 and Sox9 function.
Guo, J.K. and Hammes, A. and Chaboissier, M.C. and Vidal, V. and Xing, Y. and Wong, F. and Schedl, A.
Novartis Foundation Symposium 244 : 23-31. 1 March 2002

WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis.
Guo, J.K. and Menke, A.L. and Gubler, M.C. and Clarke, A.R. and Harrison, D. and Hammes, A. and Hastie, N.D. and Schedl, A.
Human Molecular Genetics 11 (6): 651-659. 1 January 2002


Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation.
Hammes, A. and Guo, J.K. and Lutsch, G. and Leheste, J.R. and Landrock, D. and Ziegler, U. and Gubler, M.C. and Schedl, A.
Cell 106 (3): 319-329. 10 August 2001

Overexpression of sarcolemmal calcium pump attenuates induction of cardiac gene expression in response to ET-1.
Piuhola, J. and Hammes, A. and Schuh, K. and Neyses, L. and Vuolteenaho, O. and Ruskoaho, H.
American Journal of Physiology Regulatory Integrative and Comparative Physiology 281 (3): R699-R705. 1 January 2001


Overexpression of the sarcolemmal calcium pump in the myocardium of transgenic rats.
Hammes, A. and Oberdorf-Maass, S. and Rother, T. and Nething, K. and Gollnick, F. and Linz, K.W. and Meyer, R. and Hu, K. and Han, H. and Gaudron, P. and Ertl, G. and Hoffmann, S. and Ganten, U. and Vetter, R. and Schuh, K. and Benkwitz, C. and Zimmer, H.G. and Neyses, L.
Circulation Research 83 (9): 877-888. 2 November 1998

This list was generated on Tue Jun 15 02:26:16 2021 CEST.
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