Browse by Research Team

2017

Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy.
Sedaghat-Hamedani, F. and Haas, J. and Zhu, F. and Geier, C. and Kayvanpour, E. and Liss, M. and Lai, A. and Frese, K. and Pribe-Wolferts, R. and Amr, A. and Li, D.T. and Samani, O.S. and Carstensen, A. and Bordalo, D.M. and Müller, M. and Fischer, C. and Shao, J. and Wang, J. and Nie, M. and Yuan, L. and Haßfeld, S. and Schwartz, C. and Zhou, M. and Zhou, Z. and Shu, Y. and Wang, M. and Huang, K. and Zeng, Q. and Cheng, L. and Fehlmann, T. and Ehlermann, P. and Keller, A. and Dieterich, C. and Streckfuß-Bömeke, K. and Liao, Y. and Gotthardt, M. and Katus, H.A. and Meder, B.
European Heart Journal 38 (46): 3449-3460. 7 December 2017

2014

199th ENMC international workshop: FHL1 related myopathies, June 7-9, 2013, Naarden, The Netherlands.
Bertrand, A.T. and Boennemann, C.G. and Bonne, G.
Neuromuscular Disorders 24 (5): 453-462. May 2014

2012

Guiding the molecular diagnosis of hypertrophic cardiomyopathy.
Geier, C. and Schulze-Bahr, E. and Bonne, G.
Journal of Thoracic and Cardiovascular Surgery 143 (5): 1234. May 2012

2011

Novel correlations between the genotype and the phenotype of hypertrophic and dilated cardiomyopathy: results from the German Competence Network Heart Failure.
Waldmueller, S. and Erdmann, J. and Binner, P. and Gelbrich, G. and Pankuweit, S. and Geier, C. and Timmermann, B. and Haremza, J. and Perrot, A. and Scheer, S. and Wachter, R. and Schulze-Waltrup, N. and Dermintzoglou, A. and Schoenberger, J. and Zeh, W. and Jurmann, B. and Brodherr, T. and Boergel, J. and Farr, M. and Milting, H. and Blankenfeldt, W. and Reinhardt, R. and Oezcelik, C. and Osterziel, K.J. and Loeffler, M. and Maisch, B. and Regitz-Zagrosek, V. and Schunkert, H. and Scheffold, T.
European Journal of Heart Failure 13 (11): 1185-1192. November 2011

2010

Plasma HER2 levels are not associated with cardiac function or hypertrophy in control subjects and heart failure patients.
Posch, M.G. and Panek, A. and Kersten, A. and Ghadge, S.K. and Geier, C. and Richter, S. and Perrot, A. and Gailani, M. and Dietz, R. and Lueftner, D. and Oezcelik, C.
International Journal of Cardiology 145 (1): 105-106. 5 November 2010

"MLP: A Stress Sensor Goes Nuclear" By Sylvia Gunkel, Joerg Heineke, Denise Hilfiker-Kleiner, Ralph Knoell, J Mol Cell Cardiol. 2009;47(4):423-5.
Gehmlich, K. and Ehler, E. and Perrot, A. and Fuerst, D.O. and Geier, C.
Journal of Molecular and Cellular Cardiology 48 (2): 424-425. February 2010

Contractures and hypertrophic cardiomyopathy in a novel FHL1 mutation.
Knoblauch, H. and Geier, C. and Adams, S. and Budde, B. and Rudolph, A. and Zacharias, U. and Schulz-Menger, J. and Spuler, A. and Yaou, R.B. and Nuernberg, P. and Voit, T. and Bonne, G. and Spuler, S.
Annals of Neurology 67 (1): 136-140. January 2010

2009

Connective tissue growth factor overexpression in cardiomyocytes promotes cardiac hypertrophy and protection against pressure overload.
Panek, A.N. and Posch, M.G. and Alenina, N. and Ghadge, S.K. and Erdmann, B. and Popova, E. and Perrot, A. and Geier, C. and Dietz, R. and Morano, I. and Bader, M. and Oezcelik, C.
PLoS ONE 4 (8): e6743. 25 August 2009

Genetic deletion of arginine 14 in phospholamban causes dilated cardiomyopathy with attenuated electrocardiographic R amplitudes.
Posch, M.G. and Perrot, A. and Geier, C. and Boldt, L.H. and Schmidt, G. and Lehmkuhl, H.B. and Hetzer, R. and Dietz, R. and Gutberlet, M. and Haverkamp, W. and Oezcelik, C.
Heart Rhythm 6 (4): 480-486. April 2009

2008

Back to square one: what do we know about the functions of muscle LIM protein in the heart?
Gehmlich, K. and Geier, C. and Milting, H. and Fuerst, D. and Ehler, E.
Journal of Muscle Research and Cell Motility 29 (6-8): 155-158. December 2008

Beyond the sarcomere: CSRP3 mutations cause hypertrophic cardiomyopathy.
Geier, C. and Gehmlich, K. and Ehler, E. and Hassfeld, S. and Perrot, A. and Hayess, K. and Cardim, N. and Wenzel, K. and Erdmann, B. and Krackhardt, F. and Posch, M.G. and Bublak, A. and Naegele, H. and Scheffold, T. and Dietz, R. and Chien, K.R. and Spuler, S. and Fuerst, D.O. and Nuernberg, P. and Oezcelik, C.
Human Molecular Genetics 17 (18): 2753-2765. 15 September 2008

A missense variant in desmoglein-2 predisposes to dilated cardiomyopathy.
Posch, M.G. and Posch, M.J. and Geier, C. and Erdmann, B. and Mueller, W. and Richter, A. and Ruppert, V. and Pankuweit, S. and Maisch, B. and Perrot, A. and Buttgereit, J. and Dietz, R. and Haverkamp, W. and Oezcelik, C.
Molecular Genetics and Metabolism 95 (1-2): 74-80. September 2008

Sequence analysis of myozenin 2 in 438 European patients with familial hypertrophic cardiomyopathy.
Posch, M.G. and Thiemann, L. and Tomasov, P. and Veselka, J. and Cardim, N. and Garcia-Castro, M. and Coto, E. and Perrot, A. and Geier, C. and Dietz, R. and Haverkamp, W. and Oezcelik, C.
Medical Science Monitor 14 (7): CR372-CR374. 1 July 2008

A DNA resequencing array for pathogenic mutation detection in hypertrophic cardiomyopathy.
Fokstuen, S. and Lyle, R. and Munoz, A. and Gehrig, C. and Lerch, R. and Perrot, A. and Osterziel, K.J. and Geier, C. and Beghetti, M. and Mach, F. and Sztajzel, J. and Sigwart, U. and Antonarakis, S.E. and Blouin, J.L.
Human Mutation 29 (6): 879-885. June 2008

Hypertrophic cardiomyopathy - a matter of genes.
Geier, C. and Elgeti, T. and Ozcelik, C.
Canadian Journal of Anaesthesia 55 (5): 309-311. May 2008

Subacute coronary stent thrombosis in cancer patients.
Gross, C.M. and Posch, M.G. and Geier, C. and Olthoff, H. and Kraemer, J. and Dechend, R. and Dietz, R. and Oezcelik, C.
Journal of the American College of Cardiology 51 (12): 1232-1233. 25 March 2008

Mutations in GATA4, NKX2.5, CRELD1, and BMP4 are infrequently found in patients with congenital cardiac septal defects.
Posch, M.G. and Perrot, A. and Schmitt, K. and Mittelhaus, S. and Esenwein, E.M. and Stiller, B. and Geier, C. and Dietz, R. and Gessner, R. and Oezcelik, C. and Berger, F.
American Journal of Medical Genetics A 146 (2): 251-253. 15 January 2008

Mitochondrial transcription factors TFA, TFB1 and TFB2: A search for DNA variants/haplotypes and the risk of cardiac hypertrophy.
Alonso-Montes, C. and Castro, M.G. and Reguero, J.R. and Perrot, A. and Oezcelik, C. and Geier, C. and Posch, M.G. and Moris, C. and Alvarez, V. and Ruiz-Ortega, M. and Coto, E.
Disease Markers 25 (3): 131-139. 2008

2007

Dysfunction of dysferlin-deficient hearts.
Wenzel, K. and Geier, C. and Qadri, F. and Huebner, N. and Schulz, H. and Erdmann, B. and Gross, V. and Bauer, D. and Dechend, R. and Dietz, R. and Osterziel, K.J. and Spuler, S. and Oezcelik, C.
Journal of Molecular Medicine 85 (11): 1203-1214. November 2007

Letter by Geier et al regarding article, "Hypertrophic cardiomyopathy is predominantly a disease of left ventricular outflow tract obstruction".
Geier, C. and Perrot, A. and Oezcelik, C.
Circulation 115 (23): e622. 12 June 2007

Recurrent in-stent restenosis is not associated with the angiotensin-converting enzyme D/I, angiotensinogen Thr174Met and Met235Thr, and the angiotensin-II receptor 1 A1166C polymorphism.
Gross, C.M. and Perrot, A. and Geier, C. and Posch, M.G. and Hassfeld, S. and Kramer, J. and Schmidt, S. and Derer, W. and Dietz, R. and Oezcelik, C.
Journal of Invasive Cardiology 19 (6): 261-264. 1 June 2007

Insulin-like growth factor-binding proteins 2 and 3 are independent predictors of a poor prognosis in patients with dilated cardiomyopathy.
Hassfeld, S. and Eichhorn, C. and Stehr, K. and Naegele, H. and Geier, C. and Steeg, M. and Ranke, M.B. and Oezcelik, C. and Osterziel, K.J.
Heart 93 (3): 359-360. 1 March 2007

2006

Mutations in the EGF-CFC gene Cryptic are an infrequent cause of congenital heart disease.
Oezcelik, C. and Bit-Avragim, N. and Panek, A. and Gaio, U. and Geier, C. and Lange, P.E. and Dietz, R. and Posch, M.G. and Perrot, A. and Stiller, B.
Pediatric Cardiology 27 (6): 695-698. December 2006

Genetic and phenotypic analysis of dilated cardiomyopathy with conduction system disease: Demand for strategies in the management of presymptomatic lamin A/C mutant carriers.
Perrot, A. and Sigusch, H.H. and Naegele, H. and Genschel, J. and Lehmkuhl, H. and Hetzer, R. and Geier, C. and Perez, L.V. and Reinhard, D. and Dietz, R. and Osterziel, K.J. and Schmidt, H.H.
European Journal of Heart Failure 8 (5): 484-493. August 2006

Constitutive upregulations of titin-based signalling proteins in KY deficient muscles.
Beatham, J. and Gehmlich, K. and van der Ven, P.F.M. and Sarparanta, J. and Williams, D. and Underhill, P. and Geier, C. and Fuerst, D.O. and Udd, B. and Blanco, G.
Neuromuscular Disorders 16 (7): 437-445. July 2006

Novel sequence variants in dysferlin-deficient muscular dystrophy leading to mRNA decay and possible C2-domain misfolding.
Wenzel, K. and Carl, M. and Perrot, A. and Zabojszcza, J. and Assadi, M. and Ebeling, M. and Geier, C. and Robinson, P.N. and Kress, W. and Osterziel, K.J. and Spuler, S.
Human Mutation 27 : 599-600. June 2006

2005

Familiaere dilatative Kardiomyopathie [Familial dilated cardiomyopathy].
Osterziel, K.J. and Hassfeld, S. and Geier, C. and Perrot, A.
Herz 30 : 529-534. 1 September 2005

A new LMNA mutation causing limb girdle muscular dystrophy 1B.
Spuler, S. and Geier, C. and Osterziel, K.J. and Gutberlet, M. and Genschel, J. and Lehmann, T.N. and Zinn-Justin, S. and Gilquin, B. and Schmidt, H.
Journal of Neurology 252 (5): 621-623. May 2005

Der ploetzliche Herztod bei familiaerer hypertropher Kardiomyopathie. Identifizierung von Hochrisikopatienten [Sudden cardiac death in familial hypertrophic cardiomyopathy. Identification of high-risk patients].
Pellnitz, C. and Geier, C. and Perrot, A. and Dietz, R. and Osterziel, K.J. and Haverkamp, W.
Deutsche Medizinische Wochenschrift 130 : 1150-1154. 1 January 2005

Kardiale Manifestationen bei Muskeldystrophien [Cardiac manifestations of muscular dystrophies].
Perrot, A. and Spuler, S. and Geier, C. and Dietz, R. and Osterziel, K.J.
Zeitschrift fuer Kardiologie 94 : 312-320. 1 January 2005

2003

Mutations in the human muscle LIM protein gene in families with hypertrophic cardiomyopathy.
Geier, C. and Perrot, A. and Ozcelik, C. and Binner, P. and Counsell, D. and Hoffmann, K. and Pilz, B. and Martiniak, Y. and Gehmlich, K. and van der Ven, P.F.M. and Furst, D.O. and Vornwald, A. and von Hodenberg, E. and Nuernberg, P. and Scheffold, T. and Dietz, R. and Osterziel, K.J.
Circulation 107 (10): 1390-1395. 18 March 2003

2001

Distribution and transport of cholesterol in Caenorhabditis elegans.
Matyash, V. and Geier, C. and Henske, A. and Mukherjee, S. and Hirsh, D. and Thiele, C. and Grant, B. and Maxfield, F.R. and Kurzchalia, T.V.
Molecular Biology of the Cell 12 (6): 1725-1736. June 2001