Analytical and Bioanalytical Chemistry
Differential proteomic analysis of mouse macrophages exposed to adsorbate-loaded heavy fuel oil derived combustion particles using an automated sample-preparation workflow.
Kanashova, T. 
ORCID: https://orcid.org/0000-0001-8841-5785, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Orasche, J., Karg, E., Harndorf, H., Stengel, B., Sklorz, M., Streibel, T., Zimmermann, R. and Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623
Analytical and Bioanalytical Chemistry 407
(20): 5965-5976.
August 2015
Biochemical Journal
The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2: a phosphatidylserine flippase.
Theorin, L., Faxén, K., Sørensen, D.M., Migotti, R. ORCID: https://orcid.org/0000-0001-7183-1424, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Schiller, J., Daleke, D.L., Palmgren, M., López-Marqués, R.L. and Pomorski, T.G.
Biochemical Journal 476
(5): 783-794.
6 March 2019
Biomedicines
Stable isotope-assisted untargeted metabolomics identifies ALDH1A1-driven erythronate accumulation in lung cancer cells.
Zhang, J., Keibler, M.A., Dong, W. ORCID: https://orcid.org/0000-0001-5490-4265, Ghelfi, J., Cordes, T., Kanashova, T. ORCID: https://orcid.org/0000-0001-8841-5785, Pailot, A., Linster, C.L. ORCID: https://orcid.org/0000-0001-7143-0719, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Metallo, C.M., Lautenschlaeger, T., Hiller, K. and Stephanopoulos, G.
Biomedicines 11
(10): 2842.
19 October 2023
Blood
Initiation of acute graft-versus-host disease by angiogenesis.
Riesner, K., Shi, Y., Jacobi, A., Kräter, M., Kalupa, M., McGearey, A., Mertlitz, S., Cordes, S., Schrezenmeier, J.F. ORCID: https://orcid.org/0000-0001-5239-4513, Mengwasser, J., Westphal, S., Perez-Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Schmitt, C. ORCID: https://orcid.org/0000-0002-4731-2226, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Guck, J. and Penack, O.
Blood 129
(14): 2021-2032.
6 April 2017
Cell Death Discovery
Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis.
Matthes, F., Hettich, M.M., Schilling, J., Flores-Dominguez, D., Blank, N., Wiglenda, T. ORCID: https://orcid.org/0000-0002-8460-9459, Buntru, A., Wolf, H., Weber, S., Vorberg, I. ORCID: https://orcid.org/0000-0003-0583-4015, Dagane, A., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Wanker, E. ORCID: https://orcid.org/0000-0001-8072-1630, Ehninger, D. and Krauss, S.
Cell Death Discovery 4
: 4.
29 January 2018
Cell Reports
RNF4-dependent oncogene activation by protein stabilization.
Thomas, J.J., Abed, M., Heuberger, J. ORCID: https://orcid.org/0000-0001-7205-732X, Novak, R., Zohar, Y., Beltra-Lopez, A.P., Trausch-Azar, J.S., Ilagan, M.X.G., Benhamou, D., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Kopan, R., Birchmeier, W. ORCID: https://orcid.org/0000-0003-1173-0829, Schwartz, A.L. and Orian, A.
Cell Reports 16
(12): 3388-3400.
20 September 2016
Quantitative dissection and modeling of the NF-κB p100-p105 module reveals interdependent precursor proteolysis.
Yilmaz, Z.B., Kofahl, B., Beaudette, P., Baum, K. ORCID: https://orcid.org/0000-0001-7256-0566, Ipenberg, I. ORCID: https://orcid.org/0009-0007-6788-5009, Weih, F., Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
Cell Reports 9
(5): 1756-1769.
11 December 2014
Cells
The proteomic composition and organization of constitutive heterochromatin in mouse tissues.
Schmidt, A., Zhang, H., Schmitt, S., Rausch, C., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Chen, J., Cmarko, D. ORCID: https://orcid.org/0000-0002-7467-8565, Butter, F., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Lermyte, F. ORCID: https://orcid.org/0000-0001-7371-4475 and Cardoso, M.C. ORCID: https://orcid.org/0000-0001-8427-8859
Cells 13
(2): 139.
11 January 2024
Cyclin-dependent kinase 18 controls trafficking of
aquaporin-2 and its abundance through ubiquitin
ligase STUB1, which functions as an AKAP.
Dema, A., Faust, D., Lazarow, K., Wippich, M., Neuenschwander, M. ORCID: https://orcid.org/0000-0002-3114-7975, Zühlke, K., Geelhaar, A., Pallien, T., Hallscheidt, E., Eichhorst, J., Wiesner, B., Cernecká, H., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, von Kries, J.P. ORCID: https://orcid.org/0000-0003-4716-4988 and Klussmann, E. ORCID: https://orcid.org/0000-0003-4004-5003
Cells 9
(3): 673.
10 March 2020
Chemistry & Biology
PA28αβ reduces size and increases hydrophilicity of 20S immunoproteasome peptide products.
Raule, M., Cerruti, F., Benaroudj, N., Migotti, R. ORCID: https://orcid.org/0000-0001-7183-1424, Kikuchi, J., Bachi, A., Navon, A., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Cascio, P.
Chemistry & Biology 21
(4): 470-480.
24 April 2014
Circulation Cardiovascular Genetics
Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations.
Kirchner, F., Schuetz, A. ORCID: https://orcid.org/0000-0002-0606-2574, Boldt, L.H., Martens, K., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Haverkamp, W., Thierfelder, L., Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850 and Gerull, B. ORCID: https://orcid.org/0000-0002-1363-8826
Circulation Cardiovascular Genetics 5
(4): 400-411.
1 August 2012
Circulation Research
Resolving lipid mediators maresin 1 and resolvin D2 prevent atheroprogression in mice.
Viola, J.R., Lemnitzer, P., Jansen, Y., Csaba, G., Winter, C., Neideck, C., Silvestre-Roig, C., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Doering, Y., Drechsler, M., Weber, C., Zimmer, R., Cenac, N. and Soehnlein, O.
Circulation Research 119
(9): 1030-1038.
14 October 2016
Current Biology
Ubiquitin-like protein Hub1 is required for pre-mRNA splicing and localization of an essential splicing factor in fission yeast.
Wilkinson, C.R., Dittmar, G.A. ORCID: https://orcid.org/0000-0003-3647-8623, Ohi, M.D., Uetz, P., Jones, N. and Finley, D.
Current Biology 14
: 2283-2288.
29 December 2004
EMBO Journal
The IκB kinase complex is a regulator of mRNA stability.
Mikuda, N., Kolesnichenko, M. ORCID: https://orcid.org/0000-0001-7366-9061, Beaudette, P., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Uyar, B. ORCID: https://orcid.org/0000-0002-3170-4890, Sun, W. ORCID: https://orcid.org/0000-0001-9607-1361, Tufan, A.B. ORCID: https://orcid.org/0000-0002-8734-9736, Perder, B., Akalin, A. ORCID: https://orcid.org/0000-0002-0468-0117, Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Hinz, M. ORCID: https://orcid.org/0000-0003-2611-4121 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
EMBO Journal 37
(24): e98658.
14 December 2018
The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis.
Tuorto, F., Herbst, F., Alerasool, N., Bender, S., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Federico, G., Reitter, S., Liebers, R., Stoecklin, G., Groene, H.J., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Glimm, H. and Lyko, F.
EMBO Journal 34
(18): 2350-2362.
14 September 2015
Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code.
Kowenz-Leutz, E., Pless, O. ORCID: https://orcid.org/0000-0002-1468-316X, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Knoblich, M. and Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X
EMBO Journal 29
(6): 1105-1115.
17 March 2010
EMBO Reports
SORCS1 and SORCS3 control energy balance and orexigenic peptide production.
Subkhangulova, A. ORCID: https://orcid.org/0000-0001-8843-0678, Malik, A.R. ORCID: https://orcid.org/0000-0001-7732-0756, Hermey, G. ORCID: https://orcid.org/0000-0003-4762-5262, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Rathjen, T., Poy, M.N. ORCID: https://orcid.org/0000-0002-4904-2426, Stumpf, A., Beed, P.S., Schmitz, D. ORCID: https://orcid.org/0000-0003-2741-5241, Breiderhoff, T. ORCID: https://orcid.org/0000-0002-1676-7498 and Willnow, T.E. ORCID: https://orcid.org/0000-0001-9515-7921
EMBO Reports 19
(4): e44810.
1 April 2018
FEBS Open Bio
Isolation of native plasma membrane H(+)-ATPase (Pma1p) in both the active and basal activation states.
Pedersen, J.T., Kanashova, T. ORCID: https://orcid.org/0000-0001-8841-5785, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Palmgren, M.
FEBS Open Bio 8
(5): 774-783.
May 2018
Frontiers in Molecular Neuroscience
S-palmitoylation is required for the control of growth cone morphology of DRG neurons by CNP-induced cGMP signaling.
Dumoulin, A. ORCID: https://orcid.org/0000-0002-2420-6877, Dagane, A., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Rathjen, F.G. ORCID: https://orcid.org/0000-0001-5351-613X
Frontiers in Molecular Neuroscience 11
: 345.
24 September 2018
Frontiers in Oncology
GIPC1 regulates MACC1-driven metastasis.
Siegel, F., Schmidt, H., Juneja, M., Smith, J., Herrmann, P., Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Sharma, K., Fichtner, I., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Volkmer, R., Rathjen, F.G. ORCID: https://orcid.org/0000-0001-5351-613X, Schlag, P.M. and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Frontiers in Oncology 13
: 1280977.
8 December 2023
Genome Medicine
Novel insights into proteomic technologies and their clinical perspective.
Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Genome Medicine 1
(5): 53.
21 May 2009
Haematologica
Organ siderosis and hemophagocytosis during acute graft-versus-host disease.
Nogai, A., Shi, Y., Perez-Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Cordes, S., Mengwasser, J., Mertlitz, S., Riesner, K., Kalupa, M., Erdmann, J.H., Ziebig, R., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Penack, O.
Haematologica 101
(8): e344-e346.
August 2016
Journal of Biological Chemistry
Protein kinase Ymr291w/Tda1 is essential for glucose signaling in Saccharomyces cerevisiae on the level of hexokinase isoenzyme ScHxk2 phosphorylation.
Kaps, S., Kettner, K., Migotti, R. ORCID: https://orcid.org/0000-0001-7183-1424, Kanashova, T. ORCID: https://orcid.org/0000-0001-8841-5785, Krause, U., Roedel, G., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Kriegel, T.M.
Journal of Biological Chemistry 290
(10): 6243-6255.
6 March 2015
The yeast plasma membrane ABC transporter Aus1: Purification, characterization and effect of lipids on its activity.
Marek, M., Milles, S., Schreiber, G., Daleke, D.L., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Herrmann, A., Mueller, P. and Pomorski, T.G.
Journal of Biological Chemistry 286
(24): 21835-21843.
17 June 2011
Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation.
Jerke, U. ORCID: https://orcid.org/0000-0001-6887-8010, Rolle, S. ORCID: https://orcid.org/0000-0002-1909-687X, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Bayat, B., Santoso, S., Sporbert, A. ORCID: https://orcid.org/0000-0002-3738-1295, Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199 and Kettritz, R. ORCID: https://orcid.org/0000-0001-5821-6718
Journal of Biological Chemistry 286
(9): 7070-7081.
4 March 2011
Journal of Cachexia Sarcopenia and Muscle
Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.
Lodka, D. ORCID: https://orcid.org/0009-0009-3317-6487, Pahuja, A., Geers-Knörr, C., Scheibe, R., Nowak, M. ORCID: https://orcid.org/0000-0002-0513-3254, Hamati, J., Köhncke, C., Purfürst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Kanashova, T. ORCID: https://orcid.org/0000-0001-8841-5785, Schmidt, S., Glass, D.J., Morano, I. ORCID: https://orcid.org/0000-0001-7315-2222, Heuser, A. ORCID: https://orcid.org/0000-0002-3334-960X, Kraft, T., Bassel-Duby, R., Olson, E.N., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202 and Fielitz, J. ORCID: https://orcid.org/0000-0001-8522-1045
Journal of Cachexia Sarcopenia and Muscle 7
(2): 165-180.
May 2016
Journal of Cell Science
DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.
Nowak, M. ORCID: https://orcid.org/0000-0002-0513-3254, Suenkel, B. ORCID: https://orcid.org/0000-0001-9774-4492, Porras, P. ORCID: https://orcid.org/0000-0002-8429-8793, Migotti, R. ORCID: https://orcid.org/0000-0001-7183-1424, Schmidt, F., Kny, M. ORCID: https://orcid.org/0000-0001-7132-8079, Zhu, X. ORCID: https://orcid.org/0000-0001-7858-1114, Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Fielitz, J. ORCID: https://orcid.org/0000-0001-8522-1045 and Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202
Journal of Cell Science 132
(17): jcs233395.
6 September 2019
Journal of Molecular Biology
Deregulated splicing is a major mechanism of RNA-induced toxicity in Huntington's disease.
Schilling, J., Broemer, M., Atanassov, I., Duernberger, Y., Vorberg, I., Dieterich, C. ORCID: https://orcid.org/0000-0001-9468-6311, Dagane, A., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Wanker, E. ORCID: https://orcid.org/0000-0001-8072-1630, van Roon-Mom, W., Winter, J. and Krauß, S.
Journal of Molecular Biology 431
(9): 1869-1877.
19 April 2019
Journal of Molecular Medicine
A map of human circular RNAs in clinically relevant tissues.
Maass, P.G. ORCID: https://orcid.org/0000-0002-2742-8301, Glažar, P. ORCID: https://orcid.org/0000-0003-0842-0088, Memczak, S. ORCID: https://orcid.org/0000-0001-9518-7135, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Hollfinger, I. ORCID: https://orcid.org/0000-0002-6233-8395, Schreyer, L., Sauer, A.V., Toka, O., Aiuti, A., Luft, F.C. ORCID: https://orcid.org/0000-0002-8635-1199 and Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332
Journal of Molecular Medicine 95
(11): 1179-1189.
November 2017
Clinical variability in distal spinal muscular atrophy type 1 (DSMA1): determination of steady-state IGHMBP2 protein levels in five patients with infantile and juvenile disease.
Guenther, U.P., Handoko, L., Varon, R., Stephani, U., Tsao, C.Y., Mendell, J.R., Lützkendorf, S., Hübner, C., von Au, K., Jablonka, S., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Heinemann, U. ORCID: https://orcid.org/0000-0002-8191-3850, Schuetz, A. ORCID: https://orcid.org/0000-0002-0606-2574 and Schuelke, M.
Journal of Molecular Medicine 87
(1): 31-41.
January 2009
Journal of Neuroscience
Na+/K+-ATPase is a new interacting partner for the neuronal glycine transporter GlyT2 that downregulates its expression in vitro and in vivo.
de Juan-Sanz, J., Nunez, E., Villarejo-Lopez, L., Perez-Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Rodriguez-Fraticelli, A.E., Lopez-Corcuera, B., Vazquez, J. and Aragon, C.
Journal of Neuroscience 33
(35): 14269-14281.
28 August 2013
Journal of Proteome Research
Ubiquitin profiling in liver using a transgenic mouse with biotinylated ubiquitin.
Lectez, B., Migotti, R. ORCID: https://orcid.org/0000-0001-7183-1424, Lee, S.Y., Ramirez, J., Beraza, N., Mansfield, B., Sutherland, J., Martinez-Chantar, M.L., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Mayor, U.
Journal of Proteome Research 13
(6): 3016-3026.
6 June 2014
Kidney International
Neutrophil serine proteases exert proteolytic activity on endothelial cells.
Jerke, U. ORCID: https://orcid.org/0000-0001-6887-8010, Perez Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Beaudette, P., Korkmaz, B., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Kettritz, R. ORCID: https://orcid.org/0000-0001-5821-6718
Kidney International 88
(4): 764-775.
October 2015
MethodsX
Simultaneous extraction of proteins and metabolites from cells in culture.
Sapcariu, S.C., Kanashova, T. ORCID: https://orcid.org/0000-0001-8841-5785, Weindl, D., Ghelfi, J., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Hiller, K.
MethodsX 1
(1): 74-80.
18 July 2014
Molecular & Cellular Proteomics
Using in vivo-biotinylated ubiquitin to describe a mitotic exit ubiquitome from human cells.
Min, M., Mayor, U., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Lindon, C.
Molecular & Cellular Proteomics 13
(9): 2411-2425.
September 2014
Identification of importin alpha 7 specific transport cargoes using a proteomic screening approach.
Hügel, S., Depping, R., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Rother, F. ORCID: https://orcid.org/0000-0002-4417-2192, Cabot, R., Sury, M.D., Hartmann, E. and Bader, M. ORCID: https://orcid.org/0000-0003-4780-4164
Molecular & Cellular Proteomics 13
(5): 1286-1298.
1 May 2014
Proteomic and functional consequences of hexokinase deficiency in glucose-repressible Kluyveromyces lactis.
Mates, N., Kettner, K., Heidenreich, F., Pursche, T., Migotti, R. ORCID: https://orcid.org/0000-0001-7183-1424, Kahlert, G., Kuhlisch, E., Breunig, K.D., Schellenberger, W., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Hoflack, B. and Kriegel, T.M.
Molecular & Cellular Proteomics 13
(3): 860-875.
1 March 2014
Identification of increased amounts of eppin protein complex components in sperm cells of diabetic and obese individuals by difference gel electrophoresis.
Paasch, U., Heidenreich, F., Pursche, T., Kuhlisch, E., Kettner, K., Grunewald, S., Kratzsch, J., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Glander, H.J., Hoflack, B. and Kriegel, T.M.
Molecular & Cellular Proteomics 10
(8): M110.007187.
August 2011
Molecular Cell
Translation of circRNAs.
Pamudurti, N.R. ORCID: https://orcid.org/0000-0001-9527-1118, Bartok, O., Jens, M. ORCID: https://orcid.org/0000-0002-6660-8743, Ashwal-Fluss, R., Stottmeister, C. ORCID: https://orcid.org/0000-0002-5326-6043, Ruhe, L. ORCID: https://orcid.org/0009-0003-1401-8009, Hanan, M., Wyler, E. ORCID: https://orcid.org/0000-0002-9884-1806, Perez-Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Ramberger, E. ORCID: https://orcid.org/0000-0003-2760-2696, Shenzis, S., Samson, M., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Landthaler, M. ORCID: https://orcid.org/0000-0002-1075-8734, Chekulaeva, M. ORCID: https://orcid.org/0000-0002-6868-7887, Rajewsky, N. ORCID: https://orcid.org/0000-0002-4785-4332 and Kadener, S.
Molecular Cell 66
(1): 9-21.
6 April 2017
Sequential poly-ubiquitylation by specialized conjugating enzymes expands the versatility of a quality control ubiquitin ligase.
Weber, A. ORCID: https://orcid.org/0000-0001-8889-5950, Cohen, I., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Reiss, Y., Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202, Ravid, T. and Jarosch, E. ORCID: https://orcid.org/0000-0002-5897-3492
Molecular Cell 63
(5): 827-839.
1 September 2016
Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.
Bagola, K. ORCID: https://orcid.org/0000-0003-0269-6454, von Delbrück, M., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Scheffner, M., Ziv, I., Glickman, M.H., Ciechanover, A. and Sommer, T. ORCID: https://orcid.org/0000-0001-9990-5202
Molecular Cell 50
(4): 528-539.
23 May 2013
The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO.
Mueller-Rischart, A.K., Pilsl, A., Beaudette, P., Patra, M., Hadian, K., Funke, M., Peis, R., Deinlein, A., Schweimer, C., Kuhn, P.H., Lichtenthaler, S.F., Motori, E., Hrelia, S., Wurst, W, Truembach, D., Langer, T., Krappmann, D. ORCID: https://orcid.org/0000-0001-7640-3234, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Tatzelt, J. and Winklhofer, K.F.
Molecular Cell 49
(5): 908-921.
7 March 2013
Two deubiquitylases act on mitofusin and regulate mitochondrial fusion along independent pathways.
Anton, F., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Langer, T. and Escobar-Henriques, M.
Molecular Cell 49
(3): 487-498.
7 February 2013
A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.
Hinz, M. ORCID: https://orcid.org/0000-0003-2611-4121, Stilmann, M., Coel Arslan, S., Khanna, K.K., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Scheidereit, C. ORCID: https://orcid.org/0000-0002-0446-6129
Molecular Cell 40
(1): 63-74.
8 October 2010
Molecular Metabolism
The ARFRP1-dependent Golgi scaffolding protein GOPC is required for insulin secretion from pancreatic β-cells.
Wilhelmi, Ilka, Grunwald, S. ORCID: https://orcid.org/0000-0003-3978-6277, Gimber, N. ORCID: https://orcid.org/0000-0001-9456-3063, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Arumughan, A., Wanker, E.E. ORCID: https://orcid.org/0000-0001-8072-1630, Laeger, T. ORCID: https://orcid.org/0000-0002-2763-0497, Schmoranzer, J., Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414 and Schümann, A. ORCID: https://orcid.org/0000-0002-4113-4377
Molecular Metabolism 45
: 101151.
March 2021
Molecular Neurodegeneration
Quantitative proteomic analysis of Parkin substrates in Drosophila neurons.
Martinez, A., Lectez, B., Ramirez, J., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Sutherland, J.D., Urbe, S., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Clague, M.J. and Mayor, U.
Molecular Neurodegeneration 12
(1): 29.
11 April 2017
Nature
Senescence-associated reprogramming promotes cancer stemness.
Milanovic, M. ORCID: https://orcid.org/0000-0003-1860-6003, Fan, D.N.Y. ORCID: https://orcid.org/0000-0001-6826-7076, Belenki, D. ORCID: https://orcid.org/0000-0002-9004-9849, Däbritz, J.H.M., Zhao, Z., Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Dörr, J.R. ORCID: https://orcid.org/0000-0002-4927-6548, Dimitrova, L., Lenze, D., Monteiro Barbosa, I.A., Mendoza-Parra, M.A., Kanashova, T. ORCID: https://orcid.org/0000-0001-8841-5785, Metzner, M., Pardon, K., Reimann, M. ORCID: https://orcid.org/0000-0002-7876-0128, Trumpp, A., Dörken, B. ORCID: https://orcid.org/0000-0001-7991-3643, Zuber, J., Gronemeyer, H., Hummel, M., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Lee, S. ORCID: https://orcid.org/0000-0002-4614-2931 and Schmitt, C.A. ORCID: https://orcid.org/0000-0002-4731-2226
Nature 553
(7686): 96-100.
4 January 2018
Global quantification of mammalian gene expression control.
Schwanhaeusser, B., Busse, D., Li, N. ORCID: https://orcid.org/0000-0001-6163-1648, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Schuchhardt, J., Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868, Chen, W. ORCID: https://orcid.org/0000-0003-3263-1627 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Nature 473
(7347): 337-342.
19 May 2011
Nature Cell Biology
The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells.
Stolz, A., Ertych, N., Kienitz, A., Vogel, C., Schneider, V., Fritz, B., Jacob, R., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Weichert, W., Petersen, I. and Bastians, H.
Nature Cell Biology 12
(5): 492-499.
May 2010
Proteasome subunit Rpn1 binds ubiquitin-like protein domains.
Elsasser, S., Gali, R.R., Schwickart, M., Larsen, C.N., Leggett, D.S., Mueller, B., Feng, M.T., Tuebing, F., Dittmar, G.A.G. ORCID: https://orcid.org/0000-0003-3647-8623 and Finley, D.
Nature Cell Biology 4
: 725-730.
1 September 2002
Nature Communications
Bimodal antagonism of PKA signalling by ARHGAP36.
Eccles, R.L. ORCID: https://orcid.org/0000-0002-8209-5650, Czajkowski, M.T. ORCID: https://orcid.org/0000-0002-0122-1943, Barth, C., Müller, P.M. ORCID: https://orcid.org/0000-0001-9056-4114, McShane, E. ORCID: https://orcid.org/0000-0002-7806-2063, Grunwald, S. ORCID: https://orcid.org/0000-0003-3978-6277, Beaudette, P., Mecklenburg, N., Volkmer, R., Zühlke, K., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751, Hammes, A. ORCID: https://orcid.org/0000-0003-1663-8378, Daumke, O. ORCID: https://orcid.org/0000-0002-6190-1414, Klussmann, E. ORCID: https://orcid.org/0000-0003-4004-5003, Urbé, S. and Rocks, O. ORCID: https://orcid.org/0000-0001-6349-9193
Nature Communications 7
: 12963.
7 October 2016
Nature Medicine
Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1.
Stock, K., Kumar, J., Synowitz, M., Petrosino, S., Imperatore, R., Smith, E.S.J. ORCID: https://orcid.org/0000-0002-2699-1979, Wend, P., Purfürst, B. ORCID: https://orcid.org/0000-0002-9887-7577, Nuber, U.A., Gurok, U., Matyash, V., Waelzlein, J.H., Chirasani, S.R., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Cravatt, B.F., Momma, S., Lewin, G.R. ORCID: https://orcid.org/0000-0002-2890-6352, Ligresti, A., De Petrocellis, L., Cristino, L., Di Marzo, V., Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291 and Glass, R.
Nature Medicine 18
(8): 1232-1238.
August 2012
Nature Protocols
A differential proteome screening system for post-translational modification-dependent transcription factor interactions.
Pless, O. ORCID: https://orcid.org/0000-0002-1468-316X, Kowenz-Leutz, E., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X
Nature Protocols 6
(3): 359-364.
February 2011
Neuro-Oncology
Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling.
Hu, F., a Dzaye, O.D., Hahn, A., Yu, Y. ORCID: https://orcid.org/0000-0003-1928-2514, Scavetta, R.J., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Kaczmarek, A.K., Dunning, K.R., Ricciardelli, C., Rinnenthal, J.L., Heppner, F.L., Lehnardt, S., Synowitz, M., Wolf, S.A. ORCID: https://orcid.org/0000-0003-0922-8418 and Kettenmann, H. ORCID: https://orcid.org/0000-0001-8208-0291
Neuro-Oncology 17
(2): 200-210.
February 2015
Neurobiology of Disease
Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism.
Meiser, J., Delcambre, S., Wegner, A., Jaeger, C., Ghelfi, J., D'Herouel, A.F., Dong, X., Weindl, D., Stautner, C., Nonnenmacher, Y., Michelucci, A., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Giesert, F., Schildknecht, S., Kraemer, L., Schneider, J.G., Woitalla, D., Wurst, W., Skupin, A., Weisenhorn, D.M.V., Krueger, R., Leist, M. and Hiller, K.
Neurobiology of Disease 89
: 112-125.
May 2016
Oncogene
The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.
Kobelt, D. ORCID: https://orcid.org/0000-0002-9373-0648, Perez-Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Fleuter, C., Dahlmann, M. ORCID: https://orcid.org/0000-0002-0036-5283, Zincke, F., Smith, J., Migotti, R. ORCID: https://orcid.org/0000-0001-7183-1424, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Burock, S., Walther, W. ORCID: https://orcid.org/0000-0003-2884-0231, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X and Stein, U. ORCID: https://orcid.org/0000-0001-7006-282X
Oncogene 40
(34): 5286-5301.
26 August 2021
Oncotarget
MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR.
Krause, C.J., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Thirunarayanan, N., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Lipp, M. ORCID: https://orcid.org/0000-0002-0087-2672 and Mueller, G.
Oncotarget 7
(9): 10414-10432.
1 March 2016
PLoS Genetics
Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae.
Kruegel, U., Robison, B., Dange, T., Kahlert, G., Delaney, J.R., Kotireddy, S., Tsuchiya, M., Tsuchiyama, S., Murakami, C.J., Schleit, J., Sutphin, G., Carr, D., Tar, K., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Kaeberlein, M., Kennedy, B.K. and Schmidt, M.
PLoS Genetics 7
(9): e1002253.
September 2011
PLoS ONE
Purification and characterisation of the yeast plasma membrane ATP binding cassette transporter Pdr11p.
Laub, K.R., Marek, M., Stanchev, L.D., Herrera, S.A., Kanashova, T. ORCID: https://orcid.org/0000-0001-8841-5785, Bourmaud, A., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Guenther Pomorski, T.
PLoS ONE 12
(9): e0184236.
18 September 2017
Metabolic profiling as well as stable isotope assisted metabolic and proteomic analysis of RAW 264.7 macrophages exposed to ship engine aerosol emissions: different effects of heavy fuel Oil and refined diesel fuel.
Sapcariu, S.C., Kanashova, T. ORCID: https://orcid.org/0000-0001-8841-5785, Dilger, M., Diabate, S., Oeder, S., Passig, J., Radischat, C., Buters, J., Sippula, O., Streibel, T., Paur, H.R., Schlager, C., Muelhopt, S., Stengel, B., Rabe, R., Harndorf, H., Krebs, T., Karg, E., Groeger, T., Weiss, C., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Hiller, K. and Zimmermann, R.
PLoS ONE 11
(6): e0157964.
27 June 2016
Proteomic analysis of the ubiquitin landscape in the drosophila embryonic nervous system and the adult photoreceptor cells.
Ramirez, J., Martinez, A., Lectez, B., Lee, S.Y., Franco, M., Barrio, R., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Mayor, U.
PLoS ONE 10
(10): e0139083.
13 October 2015
Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions.
Oeder, S., Kanashova, T. ORCID: https://orcid.org/0000-0001-8841-5785, Sippula, O., Sapcariu, S.C., Streibel, T., Arteaga-Salas, J.M., Passig, J., Dilger, M., Paur, H.R., Schlager, C., Muelhopt, S., Diabate, S., Weiss, C., Stengel, B., Rabe, R., Harndorf, H., Torvela, T., Jokiniemi, J.K., Hirvonen, M.R., Schmidt-Weber, C., Traidl-Hoffmann, C., BeruBe, K.A., Wlodarczyk, A.J., Prytherch, Z., Michalke, B., Krebs, T., Prevot, A.S.H., Kelbg, M., Tiggesbaeumker, J., Karg, E., Jakobi, G., Scholtes, S., Schnelle-Kreis, J., Lintelmann, J., Matuschek, G., Sklorz, M., Klingbeil, S., Orasche, J., Richthammer, P., Mueller, L., Elsasser, M., Reda, A., Groeger, T., Weggler, B., Schwemer, T., Czech, H., Rueger, C.P., Abbaszade, G., Radischat, C., Hiller, K., Buters, J.T.M., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Zimmermann, R.
PLoS ONE 10
(6): e0126536.
3 June 2015
Inflammation-induced acute phase response in skeletal muscle and critical illness myopathy.
Langhans, C., Weber-Carstens, S., Schmidt, F., Hamati, J., Kny, M. ORCID: https://orcid.org/0000-0001-7132-8079, Zhu, X. ORCID: https://orcid.org/0000-0001-7858-1114, Wollersheim, T., Koch, S., Krebs, M., Schulz, H. ORCID: https://orcid.org/0000-0002-0226-964X, Lodka, D. ORCID: https://orcid.org/0009-0009-3317-6487, Saar, K. ORCID: https://orcid.org/0000-0002-4483-1557, Labeit, S., Spies, C., Hubner, N. ORCID: https://orcid.org/0000-0002-1218-6223, Spranger, J., Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117, Boschmann, M. ORCID: https://orcid.org/0000-0002-0114-7114, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Butler-Browne, G., Mouly, V. and Fielitz, J. ORCID: https://orcid.org/0000-0001-8522-1045
PLoS ONE 9
(3): e92048.
20 March 2014
Proteomes
Tissue specific labeling in proteomics.
Ramberger, E. ORCID: https://orcid.org/0000-0003-2760-2696 and Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623
Proteomes 5
(3): E17.
18 July 2017
Proteomics
Proteomic techniques to probe the ubiquitin landscape.
Beaudette, P., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666 and Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623
Proteomics 16
(2): 273-287.
January 2016
Global analysis of cellular protein translation by pulsed SILAC.
Schwanhaeusser, B., Gossen, M. ORCID: https://orcid.org/0000-0002-1761-4063, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Proteomics 9
(1): 205-209.
January 2009
Proteomics Clinical Applications
SILAC for biomarker discovery.
Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Selbach, M. ORCID: https://orcid.org/0000-0003-2454-8751
Proteomics Clinical Applications 9
(3-4): 301-306.
April 2015
Science
Role of a ubiquitin-like modification in polarized morphogenesis.
Dittmar, G.A.G. ORCID: https://orcid.org/0000-0003-3647-8623, Wilkinson, C.R.M., Jedrzejewski, P.T. and Finley, D.
Science 295
: 2442-2446.
29 March 2002
Scientific Reports
Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue.
Grunwald, S.A. ORCID: https://orcid.org/0000-0002-3899-5424, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Haafke, S., Jedraszczak, N., Grieben, U. ORCID: https://orcid.org/0000-0002-6252-8738, Saar, K. ORCID: https://orcid.org/0000-0002-4483-1557, Patone, G., Kress, W., Steinhagen-Thiessen, E., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Spuler, S. ORCID: https://orcid.org/0000-0002-0155-1117
Scientific Reports 10
: 2158.
7 February 2020
Unique properties of PTEN-L contribute to neuroprotection in response to ischemic-like stress.
Jochner, M.C.E., An, J., Lättig-Tünnemann, G. ORCID: https://orcid.org/0000-0001-6485-1136, Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Dagane, A., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Dirnagl, U., Eickholt, B.J. and Harms, C. ORCID: https://orcid.org/0000-0002-2063-2860
Scientific Reports 9
(1): 3183.
28 February 2019
Transcription
Crosstalk between phosphorylation and multi-site arginine/lysine methylation in C/EBPs.
Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X, Pless, O. ORCID: https://orcid.org/0000-0002-1468-316X, Lappe, M., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Kowenz-Leutz, E.
Transcription 2
(1): 3-8.
January 2011
bioRxiv
Rub1/NEDD8, a ubiquitin-like modifier, is also a ubiquitin modifier.
Zerath Gurevich, S., Sinha, A., Longworth, J., Singh, R.K., Lemma, B.E., Thakur, A., Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Kornitzer, D., Reis, N., Scheffner, M., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Pick, E., Fushman, D. and Glickman, M.H.
bioRxiv
: 2020.06.18.159145.
19 June 2020
eLife
Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1.
Zhao, X., Nedvetsky, P., Stanchi, F. ORCID: https://orcid.org/0000-0003-3393-2472, Vion, A.C. ORCID: https://orcid.org/0000-0002-2788-2512, Popp, O. ORCID: https://orcid.org/0000-0001-6240-4666, Zühlke, K., Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Klussmann, E. ORCID: https://orcid.org/0000-0003-4004-5003 and Gerhardt, H. ORCID: https://orcid.org/0000-0002-3030-0384
eLife 8
: e46380.
3 October 2019
iScience
PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.
Ramberger, E. ORCID: https://orcid.org/0000-0003-2760-2696, Sapozhnikova, V., Kowenz-Leutz, E., Zimmermann, K., Nicot, N., Nazarov, P.V., Perez-Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Reimer, U., Mertins, P. ORCID: https://orcid.org/0000-0002-2245-528X, Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623 and Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X
iScience 24
(6): 102686.
25 June 2021
PRISMA: Protein Interaction Screen on Peptide Matrix reveals interaction footprints and modifications- dependent interactome of intrinsically disordered C/EBPb.
Dittmar, G. ORCID: https://orcid.org/0000-0003-3647-8623, Perez Hernandez, D. ORCID: https://orcid.org/0000-0003-0266-9050, Kowenz-Leutz, E., Kirchner, M. ORCID: https://orcid.org/0000-0002-7049-534X, Kahlert, G., Wesolowski, R. ORCID: https://orcid.org/0009-0002-7228-1051, Baum, K. ORCID: https://orcid.org/0000-0001-7256-0566, Knoblich, M., Hofstätter, M. ORCID: https://orcid.org/0000-0002-6198-2859, Muller, A., Wolf, J. ORCID: https://orcid.org/0000-0003-3254-5868, Reimer, U. and Leutz, A. ORCID: https://orcid.org/0000-0001-8259-927X
iScience 13
: 351-370.
29 March 2019
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