Browse by Research Team

2024

Visualizing the modification landscape of the human 60S ribosomal subunit at close to atomic resolution.
Wiechert, F., Unbehaun, A., Sprink, T., Seibel, H., Bürger, J., Loerke, J., Mielke, T., Diebolder, C.A., Schacherl, M. and Spahn, C.M.T.
Nucleic Acids Research : gkae1191. 10 December 2024 (In Press)

Structural characterization of Thogoto Virus nucleoprotein provides insights into viral RNA encapsidation and RNP assembly.
Dick, A., Mikirtumov, V., Fuchs, J., Krupp, F., Olal, D., Bendl, E., Sprink, T., Diebolder, C., Kudryashev, M., Kochs, G., Roske, Y. and Daumke, O.
Structure 32 (8): 1068-1078. 8 August 2024

Structural basis of Fusobacterium nucleatum adhesin Fap2 interaction with receptors on cancer and immune cells.
Schöpf, F., Marongiu, G.L., Milaj, K., Sprink, T., Kikhney, J., Moter, A. and Roderer, D.
bioRxiv : 2024.02.28.582045. 1 March 2024

Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Flügel, T., Schacherl, M., Unbehaun, A., Schroeer, B., Dabrowski, M., Bürger, J., Mielke, T., Sprink, T., Diebolder, C.A., Guillén Schlippe, Y.V. and Spahn, C.M.T.
Nature Communications 15 (1): 1756. 26 February 2024

2023

Streamlined structure determination by cryo-electron tomography and subtomogram averaging using TomoBEAR.
Balyschew, N., Yushkevich, A., Mikirtumov, V., Sanchez, R.M., Sprink, T. and Kudryashev, M.
Nature Communications 14 (1): 6543. 17 October 2023

2022

Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments.
Melo, A.A., Sprink, T., Noel, J.K., Vázquez-Sarandeses, E., van Hoorn, C., Mohd, S., Loerke, J., Spahn, C.M.T. and Daumke, O.
Nature Communications 13 (1): 7641. 10 December 2022

2021

The polygonal cell shape and surface protein layer of anaerobic methane-oxidizing (methylomirabilis lanthanidiphila) bacteria.
Gambelli, L., Mesman, R., Versantvoort, W., Diebolder, C.A., Engel, A., Evers, W., Jetten, M.S.M., Pabst, M., Daum, B. and van Niftrik, L.
Frontiers in Microbiology 12 : 766527. 1 December 2021

From tube to structure: SPA Cryo-EM workflow using apoferritin as an example.
Diebolder, C.A., Dillard, R.S. and Renault, L.
Methods in Molecular Biology 2305 (2305): 229-256. 6 May 2021

2020

Teichoic acids anchor distinct cell wall lamellae in an apically growing bacterium.
Ultee, E., van der Aart, L.T., Zhang, L., van Dissel, D., Diebolder, C.A., van Wezel, G.P., Claessen, D. and Briegel, A.
Communications Biology 3 (1): 314. 17 June 2020

2019

Integrative approaches in structural biology: a more complete picture from the combination of individual techniques.
Cerofolini, L., Fragai, M., Ravera, E., Diebolder, C.A., Renault, L. and Calderone, V.
Biomolecules 9 (8): 370. 14 August 2019

A semisynthetic peptide-metalloporphyrin responsive matrix for artificial photosynthesis.
Sun, Z., Diebolder, C.A., Renault, L. and de Groot, H.
ChemPhotoChem 3 (8): 630-635. August 2019

(In situ) conformational changes of the Escherichia coli serine chemoreceptor in different signaling states.
Yang, W., Cassidy, C.K., Ames, P., Diebolder, C.A., Schulten, K., Luthey-Schulten, Z., Parkinson, J.S. and Briegel, A.
mBio 10 (4): e00973. 2 July 2019

Insights into IgM-mediated complement activation based on in situ structures of IgM-C1-C4b.
Sharp, T.H., Boyle, A.L., Diebolder, C.A., Kros, A., Koster, A. and Gros, P.
Proceedings of the National Academy of Sciences of the United States of America 116 (24): 11900-11905. 11 June 2019

2016

Structure of AP205 coat protein reveals circular permutation in ssRNA bacteriophages.
Shishovs, M., Rumnieks, J., Diebolder, C., Jaudzems, K., Andreas, L.B., Stanek, J., Kazaks, A., Kotelovica, S., Akopjana, I., Pintacuda, G., Koning, R.I. and Tars, K.
Journal of Molecular Biology 428 (21): 4267-4279. 23 October 2016

2015

Cryoelectron tomography of the NAIP5/NLRC4 inflammasome: implications for NLR activation.
Diebolder, C.A., Halff, E.F., Koster, A.J., Huizinga, E.G. and Koning, R.I.
Structure 23 (12): 2349-2357. 1 December 2015

Conical Fourier shell correlation applied to electron tomograms.
Diebolder, C.A., Faas, F.G.A., Koster, A.J. and Koning, R.I.
Journal of Structural Biology 190 (2): 215-223. May 2015

2014

Complement is activated by IgG hexamers assembled at the cell surface.
Diebolder, C.A., Beurskens, F.J., de Jong, R.N., Koning, R.I., Strumane, K., Lindorfer, M.A., Voorhorst, M., Ugurlar, D., Rosati, S., Heck, A.J.R., van de Winkel, J.G.J., Wilson, I.A., Koster, A.J., Taylor, R.P., Saphire, E.O., Burton, D.R., Schuurman, J., Gros, P. and Parren, P.W.H.I
Science 343 (6176): 1260-3. 14 March 2014

2013

Localization of fluorescently labeled structures in frozen-hydrated samples using integrated light electron microscopy.
Faas, F.G.A., Bárcena, M., Agronskaia, A.V., Gerritsen, H.C., Moscicka, K.B., Diebolder, C.A., van Driel, L.F., Limpens, R.W.A.L., Bos, E., Ravelli, R.B.G., Koning, R.I. and Koster, A.J.
Journal of Structural Biology 181 (3): 283-290. March 2013

2012

Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin.
Halff, E.F., Diebolder, C.A., Versteeg, M., Schouten, A., Brondijk, T.H.C. and Huizinga, E.G.
Journal of Biological Chemistry 287 (46): 38460-38472. 9 November 2012

Pushing the resolution limits in cryo electron tomography of biological structures.
Diebolder, C.A., Koster, A.J. and Koning, R.I.
Journal of Microscopy 248 (1): 1-5. October 2012