Browse by Research Team

Article

Polymerization of proteins into amyloid protofibrils shares common critical oligomeric states but differs in the mechanisms of their formation.
Modler, A.J., Fabian, H., Sokolowski, F., Lutsch, G., Gast, K. and Damaschun, G.
Amyloid 11 (4): 215-231. 1 January 2004

Effect of environmental conditions on aggregation and fibril formation of barstar.
Gast, K., Modler, A.J., Damaschun, H., Kroeber, R., Lutsch, G., Zirwer, D., Golbik, R. and Damaschun, G.
European Biophysics Journal with Biophysics Letters 32 (8): 710-723. December 2003

Are there temperature-dependent structural transitions in the "intrinsically unstructured" protein prothymosin α?
Gast, K., Zirwer, D. and Damaschun, G.
European Biophysics Journal with Biophysics Letters 31 (8): 586-594. February 2003

Assembly of amyloid protofibrils via critical oligomers - A novel pathway of amyloid formation.
Modler, A.J., Gast, K., Lutsch, G. and Damaschun, G.
Journal of Molecular Biology 325 (1): 135-148. 3 January 2003

Fluoroalcohol-induced structural changes of proteins: some aspects of cosolvent-protein interactions.
Gast, K., Siemer, A., Zirwer, D. and Damaschun, G.
European Biophysics Journal with Biophysics Letters 30 (4): 273-283. 1 January 2001

Self-assembly of yeast PGK into amploid structure.
Gast, K., Damaschun, G., Damaschun, H., Fabian, H., Kroeber, R., Lutsch, G., Wieske, M. and Zirwer, D.
Nova Acta Leopoldina Suppl. 16 : 113-114. 1 January 2001

Study of the conformational transition of Abeta(1-42) using D-amino acid replacement analogues.
Janek, K., Rothemund, S., Gast, K., Beyermann, M., Zipper, J., Fabian, H., Bienert, M. and Krause, E.
Biochemistry 40 (18): 5457-5463. 1 January 2001

Conversion of yeast phosphoglycerate kinase into amyloid-like structure.
Damaschun, G., Damaschun, H., Fabian, H., Gast, K., Kroeber, R., Wieske, M. and Zirwer, D.
Proteins: Structure, Function, and Bioinformatics 39 (3): 204-211. 15 May 2000

Acetylation of faba bean legumin: conformational changes and aggregation.
Schwenke, K.D., Knopfe, C., Seifert, A., Goernitz, E. and Zirwer, D.
Journal of the Science of Food and Agriculture 81 (1): 126-134. 1 January 2000

Time-resolved dynamic light scattering as a method to monitor compaction during protein folding.
Gast, K., Zirwer, D. and Damaschun, G.
Macromolecular Symposia 162 : 205-220. 1 January 2000

Proteins can adopt totally different folded conformations.
Damaschun, G., Damaschun, H., Gast, K. and Zirwer, D.
Journal of Molecular Biology 291 : 715-725. 20 August 1999

Secondary structure and oligomerization behavior of equilibrium unfolding intermediates of the lamda Cro repressor.
Fabian, H., Faelber, K., Gast, K., Reinstaedler, D., Rogov, V.V., Naumann, D., Zamyatkin, D.F. and Filimonov, V.V.
Biochemistry 38 : 5633-5642. 27 April 1999

Trifluoroethanol-induced conformational transitions of proteins: Insights gained from the differences between alpha-lactalbumin and ribonuclease A.
Gast, K., Zirwer, D., Mueller-Frohne, M. and Damaschun, G.
Protein Science 8 : 625-634. 1 March 1999

Compactness of the kinetic molten globule of bovine alpha-lactalbumin: a dynamic light scattering study.
Gast, K., Zirwer, D., Mueller-Frohne, M. and Damaschun, G.
Protein Science 7 : 2004-2011. 1 September 1998

Initial hydrophobic collapse is not necessary for folding RNase A.
Noeppert, A., Gast, K., Zirwer, D. and Damaschun, G.
Folding & Design 3 (3): 213-221. June 1998

Folding of firefly (photinus pyralis) luciferase: aggregation and reactivation of unfolding intermediates.
Herbst, R., Gast, K. and Seckler, R.
Biochemistry 37 : 6586-6597. 1 January 1998

Conformation of thermally denatured RNase T1 with intact disulfide bonds: A study by small-angle X-ray scattering.
Damaschun, H., Gast, K., Hahn, U., Kroeber, R., Mueller-Frohne, M., Zirwer, D. and Damaschun, G.
Biochimica et Biophysica Acta 1340 : 235-244. 1 January 1997

Lack of coupling between secondary structure formation and collapse in a model polypeptide the mimics early folding intermediates, the F2 fragment of the Escherichia coli tryptophan-synthase beta chain.
Gast, K., Chaffotte, A.F., Zirwer, D., Guillou, Y., Mueller-Frohne, M., Cadieux, C., Hodges, M., Damaschun, G. and Goldberg, M.E.
Protein Science 6 : 2578-2588. 1 January 1997

Ribonuclease T1 has different dimensions in the thermally and chemically denatured states: a dynamic light scattering study.
Gast, K., Zirwer, D., Damaschun, H., Hahn, U., Mueller-Frohne, M., Wirth, M. and Damaschun, G.
FEBS Letters 403 : 245-248. 1 January 1997

Stopped-flow dynamic light scattering as a method to monitor compaction during protein folding.
Gast, K., Noeppert, A., Mueller-Frohne, M., Zirwer, D. and Damaschun, G.
European Biophysics Journal with Biophysics Letters 25 : 211-219. 1 January 1997

Transient changes of the conformation of hemagglutinin of influenza virus at low ph detected by time resolved circular dichroism spectroscopy.
Korte, T., Ludwig, K., Krumbiegel, M., Zirwer, D., Damaschun, G. and Herrmann, A.
Journal of Biological Chemistry 272 : 9764-9770. 1 January 1997

Reduced-denatured ribonuclease A is not in a compact state.
Noeppert, A., Gast, K., Mueller-Frohne, M., Zirwer, D. and Damaschun, G.
FEBS Letters 380 : 179-182. 1 January 1996

Multimodal particle size distribution or fractal surface of acrylic acid copolymer nanoparticles: A small-angle X-ray scattering study using direct Fourier and indirect maximum entropy methods.
Mueller, J.J., Hansen, S., Lukowski, G. and Gast, K.
Journal of Applied Crystallography 28 (Pt 6): 774-781. 1 December 1995

Prothymosin alpha: a biologically active protein with random coil conformation.
Gast, K., Damaschun, H., Eckert, K., Schulze-Forster, K., Maurer, H.R., Mueller-Frohne, M., Zirwer, D., Czarnecki, J. and Damaschun, G.
Biochemistry 34 (40): 13211-13218. 10 October 1995

AKIMA interpolation: A tool used in direct slit-length desmearing procedures of non-frequency- limited X-ray scattering curves.
Mueller, J.J., Mueller, E.C., Gernat, C. and Kroeber, R.
Journal of Applied Crystallography 28 (Pt 1): 38-42. 1 February 1995

Cold denaturation of yeast phosphoglycerate kinase which domain is more stable?
Gast, K., Damaschun, G., Desmadril, M., Minard, P., Mueller-Frohne, M., Pfeil, W. and Zirwer, D.
FEBS Letters 358 : 247-250. 1 January 1995

Computer simulations of X-ray scattering curves: Gelation and crystallization process in amylose solutions.
Mueller, J.J., Gernat, C., Schulz, W., Mueller, E.C., Vorwerg, W. and Damaschun, G.
Biopolymers 35 : 271-288. 1 January 1995

Acrylic acid copolymer nanoparticles for drug delivery: structural characterization of nanoparticles by small-angle x-ray scattering.
Mueller, J.J., Lukowski, G., Kroeber, R., Damaschun, G. and Dittgen, M.
Colloid and Polymer Science 272 : 755-769. 1 January 1994

The thermostability of natural variants of bacterial plasminogen- activator staphylokinase.
Gase, A., Birch-Hirschfeld, E., Guehrs, K.H., Hartmann, M., Vetterman, S., Damaschun, G., Damaschun, H., Gast, K., Misselwitz, R., Zirwer, D., Collen, D. and Schlott, B.
European Journal of Biochemistry 223 : 303-308. 1 January 1994

Compactness of protein molten globules: temperature-induced structural changes of the apomyoglobin folding intermediate.
Gast, K., Damaschun, H., Misselwitz, R., Mueller-Frohne, M., Zirwer, D. and Damaschun, G.
European Biophysics Journal with Biophysics Letters 23 (4): 297-305. 1994

Cold denaturation-induced conformational changes in phosphoglycerate kinase from yeast.
Damaschun, G., Damaschun, H., Gast, K., Misselwitz, R., Mueller, J.J., Pfeil, W. and Zirwer, D.
Biochemistry 32 (30): 7739-7746. 3 August 1993

Cold denaturation of yeast phosphoglycerate kinase: kinetics of changes in secondary structure and compactness on unfolding and refolding.
Gast, K., Damaschun, G., Damaschun, H., Misselwitz, R. and Zirwer, D.
Biochemistry 32 : 7747-7752. 1 January 1993

Crystalline parts of three different conformations detected in native and enzymatically degraded starches.
Gernat, C., Radosta, S., Anger, H. and Damaschun, G.
Starch / Staerke 45 : 309-314. 1 January 1993

Physical and conformational properties of staphylokinase in solution.
Damaschun, G., Damaschun, H., Gast, K., Misselwitz, R., Zirwer, D., Guehrs, K.H., Hartmann, M., Schlott, B., Triebel, H. and Behnke, H.
Biochimica et Biophysica Acta 1161 : 244-248. 1 January 1993

The database BIOSCAT: a tool for structure research by scattering and hydrodynamic methods.
Mueller, J.J., Pankow, H., Poppe, B. and Damaschun, G.
Journal of Applied Crystallography 25 (Pt 6): 803-806. 1 December 1992

The inertia-equivalent ellipsoid: a link between atomic structure and low-resolution models of small globular proteins determined by small-angle x-ray scattering.
Mueller, J.J. and Schrauber, H.
Journal of Applied Crystallography 25 (Pt 2): 181-191. 1 April 1992

Application of dynamic light scattering to studies of protein folding kinetics.
Gast, K., Damaschun, G., Misselwitz, R. and Zirwer, D.
European Biophysics Journal with Biophysics Letters 21 : 357-362. 1 January 1992

Measuring the in-vitro assembly of microtubules by dynamic light scattering.
Walter, A., Gast, K., Vater, W. and Zirwer, D.
Acta Histochemica (Suppl XLI): 29-35. 1 January 1992

Streptokinase is a flexible multi-domain protein.
Damaschun, G., Damaschun, H., Gast, K., Gerlach, D., Misselwitz, R., Welfle, H. and Zirwer, D.
European Biophysics Journal with Biophysics Letters 20 : 355-361. 1 January 1992

Studies on rye starch properties and modification. Part II: swelling and solubility behaviour of rye starch granules.
Radosta, S., Kettlitz, B., Schierbaum, F. and Gernat, C.
Starch / Staerke 44 : 8-14. 1 January 1992

Acid denatured apo-cytochrome c is a random coil: evidence from small-angle x-ray scattering and dynamic light scattering.
Damaschun, G., Damaschun, H., Gast, K., Gernat, C. and Zirwer, D.
Biochimica et Biophysica Acta 1078 : 289-295. 1 January 1991

Compactness of protein molecules in native and denatured states as revealed by laser light scattering and x-ray scattering.
Gast, K., Damaschun, G., Damaschun, H., Misselwitz, R. and Zirwer, D.
Biochemical Society Transactions 19 : 488. 1 January 1991

Solvent dependence of dimensions of unfolded protein chains.
Damaschun, G., Damaschun, H., Gast, K., Zirwer, D. and Bychkova, V.E.
International Journal of Biological Macromolecules 13 : 217-221. 1 January 1991

Book Section

Conformational differences between ovine and human CRF.
Dathe, M., Zirwer, D., Gast, K., Beyermann, M., Krause, F. and Bienert, M.
In: Peptides: Chemistry, Structure and Biology. Proceedings of the 13th American Peptide Symposium, June 20-25. Edmonton, Canada, 24-27. 1 January 1993

Compactness of protein molecules in native and denatured states as revealed by laser light scattering and X-ray scattering.
Gast, K., Damaschun, G., Damaschun, H., Misselwitz, R., Zirwer, D. and Bychkova, V.A.
In: Laser Light Scattering in Biochemistry. Thomas Graham House, Cambridge, 209-223. 1 January 1992

Dissociation of 11S globulins from plant seeds after succinylation - a problem of subunit interaction.
Schwenke, K.D., Zirwer, D., Gast, K., Linow, K.J., Goernitz, E., Gueguen, J. and Subirade, M.
In: Protein Interactions. VCH, Weinheim, 233-251. ISBN 3-527-28499-8 1 January 1992

Rapeseed protein-polyamin interactions.
Schwenke, K.D., Mothes, R., Gast, K. and Zirwer, D.
In: Protein Interactions. VCH, Weinheim, 255-267. ISBN 3-527-28499-8 1 January 1992

Untersuchung von flexiblen Makromolekuelen mit Roentgen- Kleinwinkelstreuung und dynamischer Lichtstreuung.
Damaschun, G., Damaschun, H., Gast, K. and Zirwer, D.
In: Strukturuntersuchungen an nichtkristallinen und partiellkristallinen Stoffen. Universitaet Rostock und Deutsche Gesellschaft fuer Kristallographie, Rostock, 10-11. 1 January 1991

Untersuchung der Roentgen-Streuung von Cytochrom C (Pferdeherz) in Loesung.
Damaschun, G., Damaschun, H., Gernat, C., Kroeber, R. and Mueller, J.J.
In: UNSPECIFIED Freiberger Praezisionsmechanik GmbH, 1-9. 1991

Book

Lehre und Ausbildung am MDC Berlin-Buch.
Damaschun, G.
Max-Delbrueck-Centrum fuer Molekulare Medizin, Berlin-Buch. 1 January 1992

Thesis

Studien zur Kinetik der Fehlfaltung und Aggregation von Proteinen.
Modler, A.J.
UNSPECIFIED thesis, UNSPECIFIED. 23 October 2003

Review

Denatured states of yeast phosphoglycerate kinase.
Damaschun, G., Damaschun, H., Gast, K. and Zirwer, D.
Biochemistry Moskau 63 : 259-275. 1 January 1998