Helicobacter pylori induces AGS cell motility and elongation via independent signaling pathways

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Item Type:	Article
Title:	Helicobacter pylori induces AGS cell motility and elongation via independent signaling pathways
Creators Name:	Moese, S., Selbach, M., Kwok, T., Brinkmann, V., Koenig, W., Meyer, T.F. and Backert, S.
Abstract:	Helicobacter pylori induces motogenic and cytoskeletal responses in gastric epithelial cells. We demonstrate that these responses can be induced via independent signaling pathways that often occur in parallel. The cag pathogenicity island appears to be nonessential for induction of motility, whereas the elongation phenotype depends on translocation and phosphorylation of CagA.
Keywords:	Bacterial Antigens, Bacterial Proteins, Cell Movement, Cultured Cells, Cytoskeleton, Epithelial Cells, Gastric Mucosa, Bacterial Gene Expression Regulation, Helicobacter pylori, Signal Transduction, Transfection, Virulence
Source:	Infection and Immunity
ISSN:	0019-9567
Publisher:	American Society for Microbiology
Volume:	72
Number:	6
Page Range:	3646-3649
Date:	June 2004
Official Publication:	https://doi.org/10.1128/IAI.72.6.3646-3649.2004
PubMed:	View item in PubMed

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