Riboswitch finder - a tool for identification of riboswitch RNAs

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Item Type:	Article
Title:	Riboswitch finder - a tool for identification of riboswitch RNAs
Creators Name:	Bengert, P. and Dandekar, T.
Abstract:	We describe a dedicated RNA motif search program and web server to identify RNA riboswitches. The Riboswitch finder analyses a given sequence using the web interface, checks specific sequence elements and secondary structure, calculates and displays the energy folding of the RNA structure and runs a number of tests including this information to determine whether high-sensitivity riboswitch motifs (or variants) according to the Bacillus subtilis type are present in the given RNA sequence. Batch-mode determination (all sequences input at once and separated by FASTA format) is also possible. The program has been implemented and is available both as local software for in-house installation and as a web server at http://www.biozentrum.uni-wuerzburg.de/bioinformatik/Riboswitch/.
Keywords:	Allosteric Regulation, Internet, Nucleic Acid Conformation, Messenger RNA, Ribonucleic Acid Regulatory Sequences, RNA Sequence Analysis, Software
Source:	Nucleic Acids Research
ISSN:	0305-1048
Publisher:	Oxford University Press
Volume:	32
Number:	Web Server Issue
Page Range:	W154-W159
Date:	1 July 2004
Official Publication:	https://doi.org/10.1093/nar/gkh352
PubMed:	View item in PubMed

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