The nature and identification of quantitative trait loci: a community's view

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Item Type:	Review
Title:	The nature and identification of quantitative trait loci: a community's view
Creators Name:	Abiola, O., Angel, J.M., Avner, P., Bachmanov, A.A., Belknap, J.K., Bennett, B., Blankenhorn, E.P., Blizard, D.A., Bolivar, V., Brockmann, G.A., Buck, K.J., Bureau, J.F., Casley, W.L., Chesler, E.J., Cheverud, J.M., Churchill, G.A., Cook, M., Crabbe, J.C., Crusio, W.E., Darvasi, A., de Haan, G., Dermant, P., Doerge, R.W., Elliot, R.W., Farber, C.R., Flaherty, L., Flint, J., Gershenfeld, H., Gibson, J.P., Gu, J., Gu, W., Himmelbauer, H., Hitzemann, R., Hsu, H.C., Hunter, K., Iraqi, F.F., Jansen, R.C., Johnson, T.E., Jones, B.C., Kempermann, G., Lammert, F., Lu, L., Manly, K.F., Matthews, D.B., Medrano, J.F., Mehrabian, M., Mittlemann, G., Mock, B.A., Mogil, J.S., Montagutelli, X., Morahan, G., Mountz, J.D., Nagase, H., Nowakowski, R.S., O'Hara, B.F., Osadchuk, A.V., Paigen, B., Palmer, A.A., Peirce, J.L., Pomp, D., Rosemann, M., Rosen, G.D., Schalkwyk, L.C., Seltzer, Z., Settle, S., Shimomura, K., Shou, S., Sikela, J.M., Siracusa, L.D., Spearow, J.L., Teuscher, C., Threadgill, D.W., Toth, L.A., Toye, A.A., Vadasz, C., Van Zant, G., Wakeland, E., Williams, R.W., Zhang, H.G. and Zou, F.
Abstract:	This white paper by eighty members of the Complex Trait Consortium presents a community's view on the approaches and statistical analyses that are needed for the identification of genetic loci that determine quantitative traits. Quantitative trait loci (QTLs) can be identified in several ways, but is there a definitive test of whether a candidate locus actually corresponds to a specific QTL?
Keywords:	Chromosome Mapping, Genetically Modified Animals, Quantitative Trait Loci, Animals
Source:	Nature Reviews Genetics
ISSN:	1471-0056
Publisher:	Nature Publishing Group
Volume:	4
Number:	11
Page Range:	911-916
Date:	1 November 2003
Official Publication:	https://doi.org/10.1038/nrg1206
PubMed:	View item in PubMed

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