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Die Rolle der Polychemotherapie im multimodalen Behandlungskonzept der malignen Knochentumoren [The role of polychemotherapy in the management of malignant bone tumors]

Item Type:Article
Title:Die Rolle der Polychemotherapie im multimodalen Behandlungskonzept der malignen Knochentumoren [The role of polychemotherapy in the management of malignant bone tumors]
Creators Name:Reichardt, P. and Doerken, B.
Abstract:Osteosarcoma,chondrosarcoma and Ewingtumors are the most common primary malignant bone tumors.Due to early hematogenous dissemination, surgery alone is able to cure less than 20% of patients with osteosarcoma. In Ewing-tumors less than 10% of patients will be cured with local treatment alone.By the use of aggressive polychemotherapy, given both pre- and post-surgery, cure rates of more than 50% for Ewing-tumors and about 70% for osteosarcoma could be achieved.Thus,chemotherapy is an indispensable part of the multimodal treatment of these tumor types. Chondrosarcomas are usually more highly differentiated and therefore show a lower rate of metastasis. The use of chemotherapy is not established in these tumors.
Keywords:Osteosarcoma, Ewing Tumors, Chondrosarcoma, Multimodality Treatment, Polychemotherapy
Source:Chirurg
ISSN:0009-4722
Publisher:Springer
Volume:73
Number:12
Page Range:1170-1173
Date:1 December 2002
Official Publication:https://doi.org/10.1007/s00104-002-0555-9
PubMed:View item in PubMed

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