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Unlocking the secrets of structural variants in a healthy tissue

Item Type:Article
Title:Unlocking the secrets of structural variants in a healthy tissue
Creators Name:Korbel, J.O. and Sanders, A.D.
Abstract:Our study explored cell-specific functional consequences and clonal expansions of mosaic structural variants in distinct hematopoietic stem and progenitor cells by utilizing advanced single-cell sequencing techniques. Our single-cell multi-omics approach paves the way for future studies to focus on the roles of somatic structural variants in aging and disease.
Source:Nature Genetics
ISSN:1061-4036
Publisher:Nature Publishing Group
Volume:56
Number:6
Page Range:1047-1048
Date:June 2024
Official Publication:https://doi.org/10.1038/s41588-024-01757-z
PubMed:View item in PubMed

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