Aquaporin-2 is not alone

Tools

Item Type:	Editorial
Title:	Aquaporin-2 is not alone
Creators Name:	Klussmann, E.
Abstract:	Arginine-vasopressin induces water reabsorption in collecting duct principal cells through the water channels aquaporin (AQP) 2, 3, and 4. Only the presence of these AQPs allows for short-term adjustments of plasma osmolality by arginine-vasopressin. How principal cells maintain the expression of the AQPs is unclear. Zhang et al., for the first time, identify a mechanism that explains the expression of the AQPs under resting conditions. They show that the transcription coregulator, yes-associated protein, is responsible for the coordinated expression of the 3 AQPs.
Keywords:	Aquaporin 2, Arginine, Arginine Vasopressin, Collecting Kidney Tubules, Vasopressins, Water / Metabolism
Source:	Kidney International
ISSN:	0085-2538
Publisher:	Nature Publishing Group
Volume:	103
Number:	3
Page Range:	458-460
Date:	March 2023
Official Publication:	https://doi.org/10.1016/j.kint.2022.11.014
PubMed:	View item in PubMed

Repository Staff Only: item control page