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Translating principles of quality control to cardiovascular magnetic resonance: assessing quantitative parameters of the left ventricle in a large cohort

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Item Type:Article
Title:Translating principles of quality control to cardiovascular magnetic resonance: assessing quantitative parameters of the left ventricle in a large cohort
Creators Name:Riazy, L., Däuber, S., Lange, S., Viezzer, D.S., Ott, S., Wiesemann, S., Blaszczyk, E., Mühlberg, F., Zange, L. and Schulz-Menger, J.
Abstract:Cardiac magnetic resonance (CMR) examinations require standardization to achieve reproducible results. Therefore, quality control as known as in other industries such as in-vitro diagnostics, could be of essential value. One such method is the statistical detection of long-time drifts of clinically relevant measurements. Starting in 2010, reports from all CMR examinations of a high-volume center were stored in a hospital information system. Quantitative parameters of the left ventricle were analyzed over time with moving averages of different window sizes. Influencing factors on the acquisition and on the downstream analysis were captured. 26,902 patient examinations were exported from the clinical information system. The moving median was compared to predefined tolerance ranges, which revealed an overall of 50 potential quality relevant changes ("alerts") in SV, EDV and LVM. Potential causes such as change of staff, scanner relocation and software changes were found not to be causal of the alerts. No other influencing factors were identified retrospectively. Statistical quality assurance systems based on moving average control charts may provide an important step towards reliability of quantitative CMR. A prospective evaluation is needed for the effective root cause analysis of quality relevant alerts.
Keywords:Cine Magnetic Resonance Imaging, Heart Ventricles, Left Ventricular Function, Magnetic Resonance Spectroscopy, Quality Control, Reproducibility of Results, Retrospective Studies, Stroke Volume
Source:Scientific Reports
ISSN:2045-2322
Publisher:Nature Publishing Group
Volume:13
Number:1
Page Range:2205
Date:7 February 2023
Official Publication:https://doi.org/10.1038/s41598-023-29028-7
PubMed:View item in PubMed

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