A cFLIP-flop switch for senolysis

Tools

Item Type:	Editorial
Title:	A cFLIP-flop switch for senolysis
Creators Name:	Fan, D.N.Y. and Schmitt, C.A.
Abstract:	Persistent senescent cancer cells have tumor-promoting potential, making their selective elimination a prime therapeutic objective. The death receptor inhibitor cFLIP has now been shown to counter the susceptibility of senescent cells to DR5-mediated extrinsic apoptosis, which can be therapeutically exploited.
Keywords:	Apoptosis, CASP8 and FADD-Like Apoptosis Regulating Protein
Source:	Nature Cancer
ISSN:	2662-1347
Publisher:	Springer Nature
Volume:	3
Number:	11
Page Range:	1279-1281
Date:	November 2022
Official Publication:	https://doi.org/10.1038/s43018-022-00455-1
PubMed:	View item in PubMed

Repository Staff Only: item control page