![[feed]](/style/images/feed-icon-14x14.png){kind=icon}
Tools
Tools
| Item Type: | Article |
|---|---|
| Title: | Validation and performance assessment of a preclinical SiPM-based SPECT/MRI insert |
| Creators Name: | Carminati, M., Baratelli, F.M., Occhipinti, M., Erlandsson, K., Nagy, K., Nyitrai, Z., Czeller, M., Kühne, A., Niendorf, T., Valtorta, S., Belloli, S., Moresco, R.M., Savi, A., Iadanza, A., Falini, A., Politi, L.S., Cadioli, M., Hutton, B.F. and Fiorini, C. |
| Abstract: | A preclinical insert for small animal simultaneous SPECT and MR imaging, in particular for imaging mouse brains, is presented. It consists of ten static magnetic resonance imaging (MRI)-compatible gamma cameras based on tiles of silicon photomultipliers readout by a multichannel ASIC and coupled to 5 cm × 5 cm CsI(Tl) scintillators and to an MRI-compatible multipinhole collimator. Calibration and image reconstruction algorithm are illustrated. Mutual compatibility is demonstrated along with imaging performance that is comparable with other non-MR micro-SPECT systems: 0.9 mm tomographic spatial resolution across a transverse field of view of 15.6 mm, 12% energy resolution (at 140 keV), and 1105 cps/MBq sensitivity. Experimental results with phantoms (glass capillaries of 290 μm diameter and a mini Derenzo) are presented. |
| Keywords: | Gamma Camera, Multimodal Imaging, Multipinhole Collimator, Silicon Photomultipliers (SiPMs) |
| Source: | IEEE Transactions on Radiation and Plasma Medical Sciences |
| ISSN: | 2469-7311 |
| Publisher: | IEEE |
| Volume: | 3 |
| Number: | 4 |
| Page Range: | 483-490 |
| Date: | July 2019 |
| Official Publication: | https://doi.org/10.1109/TRPMS.2019.2893377 |
Repository Staff Only: item control page
