Heterogeneity of diabetes: β-cells, phenotypes, and precision medicine: proceedings of an international symposium of the canadian institutes of Health Research’s Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases

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Item Type:	Article
Title:	Heterogeneity of diabetes: β-cells, phenotypes, and precision medicine: proceedings of an international symposium of the canadian institutes of Health Research’s Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases
Creators Name:	Cefalu, W.T., Andersen, D.K., Arreaza-Rubín, G., Pin, C.L., Sato, S., Verchere, C.B., Woo, M., Rosenblum, N.D., Rosenblum, N., Cefalu, W., Andersen, D.K., Arreaza-Rubín, G., Dhara, C., James, S.P., Makarchuk, M.J., Pin, C.L., Sato, S., Verchere, B., Woo, M., Powers, A., Estall, J., Hoesli, C., Millman, J., Linnemann, A., Johnson, J., Pin, C.L., Hawkins, M., Woo, M., Gloyn, A., Cefalu, W., Rosenblum, N., Huising, M.O., Benninger, R.K.P., Almaça, J., Hull-Meichle, R.L., MacDonald, P., Lynn, F., Melero-Martin, J., Yoshihara, E., Stabler, C., Sander, M., Evans-Molina, C., Engin, F., Thompson, P., Shalev, A., Redondo, M.J., Nadeau, K., Bellin, M., Udler, M.S., Dennis, J., Dash, S., Zhou, W., Snyder, M., Booth, G., Butte, A. and Florez, J.
Abstract:	One hundred years have passed since the discovery of insulin - an achievement that transformed diabetes from a fatal illness into a manageable chronic condition. The decades since that momentous achievement have brought ever more rapid innovation and advancement in diabetes research and clinical care. To celebrate the important work of the past century and help to chart a course for its continuation into the next, the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases recently held a joint international symposium, bringing together a cohort of researchers with diverse interests and backgrounds from both countries and beyond to discuss their collective quest to better understand the heterogeneity of diabetes and thus gain insights to inform new directions in diabetes treatment and prevention. This article summarizes the proceedings of that symposium, which spanned cutting-edge research into various aspects of islet biology, the heterogeneity of diabetic phenotypes, and the current state of and future prospects for precision medicine in diabetes.
Keywords:	Canada, Diabetes Mellitus, National Institute of Diabetes and Digestive and Kidney Diseases (U.S.), National Institutes of Health (U.S.), Phenotype, Precision Medicine, United States
Source:	Canadian Journal of Diabetes
ISSN:	1499-2671
Publisher:	Elsevier
Volume:	45
Number:	8
Page Range:	697-713
Date:	December 2021
Official Publication:	https://doi.org/10.1016/j.jcjd.2021.09.126
PubMed:	View item in PubMed

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