Item Type: | Editorial |
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Title: | A multi-omics roadmap of β-cell failure in type 2 diabetes mellitus |
Creators Name: | Wang, G. and Sander, M. |
Abstract: | Pancreatic β-cell dysfunction contributes to type 2 diabetes mellitus (T2DM) pathogenesis. However, human islet studies have revealed few consistent molecular changes in T2DM, owing partly to technical and biological confounding factors. A new multi-omics study of islets from well-phenotyped living donors attempts to overcome these limitations to catalogue T2DM-associated molecular changes. |
Keywords: | Gene Expression Analysis, Type 2 Diabetes |
Source: | Nature Reviews Endocrinology |
ISSN: | 1759-5029 |
Publisher: | Springer Nature |
Volume: | 17 |
Number: | 11 |
Page Range: | 641-642 |
Date: | November 2021 |
Official Publication: | https://doi.org/10.1038/s41574-021-00556-4 |
PubMed: | View item in PubMed |
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