Item Type: | Editorial |
---|---|
Title: | Transient activated fibroblasts contribute to zebrafish heart regeneration |
Creators Name: | Junker, J.P. and Panáková, D. |
Abstract: | In the zebrafish heart, several transient fibroblast types appear after injury. High-throughput lineage tracing revealed that injury-responsive fibroblasts are derived from two distinct lineage origins: the epicardium and the endocardium. Targeted cell-type-specific depletion showed that at least one fibroblast type has a critical role in heart regeneration. |
Keywords: | Cardiac Myocytes, Cell Proliferation, Fibroblasts, Heart, Regeneration, Zebrafish Proteins, Animals, Zebrafish |
Source: | Nature Genetics |
ISSN: | 1061-4036 |
Publisher: | Nature Publishing Group |
Volume: | 54 |
Number: | 8 |
Page Range: | 1076-1077 |
Date: | August 2022 |
Official Publication: | https://doi.org/10.1038/s41588-022-01130-y |
PubMed: | View item in PubMed |
Repository Staff Only: item control page