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| Item Type: | Article |
|---|---|
| Title: | Cardio-respiratory motion-corrected 3D cardiac water-fat MRI using model-based image reconstruction |
| Creators Name: | Mayer, J., Blaszczyk, E., Cipriani, A., Ferrazzi, G., Schulz-Menger, J., Schaeffter, T. and Kolbitsch, C. |
| Abstract: | PURPOSE: Myocardial fat infiltrations are associated with a range of cardiomyopathies. The purpose of this study was to perform cardio-respiratory motion-correction for model-based water-fat separation to image fatty infiltrations of the heart in a free-breathing, non-cardiac-triggered high-resolution 3D MRI acquisition. METHODS: Data were acquired in nine patients using a free-breathing, non-cardiac-triggered high-resolution 3D Dixon gradient-echo sequence and radial phase encoding trajectory. Motion correction was combined with a model-based water-fat reconstruction approach. Respiratory and cardiac motion models were estimated using a dual-mode registration algorithm incorporating both motion-resolved water and fat information. Qualitative comparisons of fat structures were made between 2D clinical routine reference scans and reformatted 3D motion-corrected images. To evaluate the effect of motion correction the local sharpness of epicardial fat structures was analyzed for motion-averaged and motion-corrected fat images. RESULTS: The reformatted 3D motion-corrected reconstructions yielded qualitatively comparable fat structures and fat structure sharpness in the heart as the standard 2D breath-hold. Respiratory motion correction improved the local sharpness on average by 32% ± 24% with maximum improvements of 81% and cardiac motion correction increased the sharpness further by another 15% ± 11% with maximum increases of 31%. One patient showed a fat infiltration in the myocardium and cardio-respiratory motion correction was able to improve its visualization in 3D. CONCLUSION: The 3D water-fat separated cardiac images were acquired during free-breathing and in a clinically feasible and predictable scan time. Compared to a motion-averaged reconstruction an increase in sharpness of fat structures by 51% ± 27% using the presented motion correction approach was observed for nine patients. |
| Keywords: | 3D Imaging, Fat, Heart, Model-Based, Motion-Correction, MRI |
| Source: | Magnetic Resonance in Medicine |
| ISSN: | 0740-3194 |
| Publisher: | Wiley |
| Volume: | 88 |
| Number: | 4 |
| Page Range: | 1561-1574 |
| Date: | October 2022 |
| Official Publication: | https://doi.org/10.1002/mrm.29284 |
| PubMed: | View item in PubMed |
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