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| Item Type: | Review |
|---|---|
| Title: | An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome |
| Creators Name: | Wirth, K.J., Scheibenbogen, C. and Paul, F. |
| Abstract: | There is accumulating evidence of endothelial dysfunction, muscle and cerebral hypoperfusion in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In this paper we deduce the pathomechanisms resulting in central nervous pathology and the myriad of neurocognitive symptoms. We outline tentative mechanisms of impaired cerebral blood flow, increase in intracranial pressure and central adrenergic hyperactivity and how they can well explain the key symptoms of cognitive impairment, brain fog, headache, hypersensitivity, sleep disturbances and dysautonomia. |
| Keywords: | Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, Post-Covid-19 Syndrome, Neurological Symptoms, Cognitive Impairment, Brain Fog, Hypersensitivity, Dysautonomia, Sleep Disturbance, Headache |
| Source: | Journal of Translational Medicine |
| ISSN: | 1479-5876 |
| Publisher: | BioMed Central |
| Volume: | 19 |
| Number: | 1 |
| Page Range: | 471 |
| Date: | 22 November 2021 |
| Additional Information: | Erratum in: J Transl Med 20(1): 25. |
| Official Publication: | https://doi.org/10.1186/s12967-021-03143-3 |
| PubMed: | View item in PubMed |
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