Diagnostik und Therapie von statinassoziierten Muskelsymptomen [Diagnostics and treatment of statin-associated muscle symptoms]

Tools

Item Type:	Article
Title:	Diagnostik und Therapie von statinassoziierten Muskelsymptomen [Diagnostics and treatment of statin-associated muscle symptoms]
Creators Name:	Kassner, U., Grunwald, S., Spira, D., Buchmann, N., Bobbert, T., Gazzerro, E., Hollstein, T., Spuler, S. and Steinhagen-Thiessen, E.
Abstract:	Statins are among the most frequently prescribed drugs in Germany. Their benefits in lowering cardiovascular risk are beyond dispute. Nevertheless, many patients complain of side effects from statin therapy, including statin-associated muscle symptoms (SAMS) in particular. Despite their relative frequency, it is difficult to objectively diagnose them, as the time until appearance of first symptoms, the nature of the complaints and the severity of muscle problems vary widely. This narrative review summarizes the causes of SAMS as well as new possibilities regarding their diagnosis and therapy.
Keywords:	Myalgia, Myopathies, HMG CoA Reductase, Creatine Kinase, Genetic Predisposition to Disease
Source:	Internist
ISSN:	0020-9554
Publisher:	Springer
Volume:	62
Page Range:	827-840
Date:	August 2021
Official Publication:	https://doi.org/10.1007/s00108-021-01059-0
PubMed:	View item in PubMed

Repository Staff Only: item control page