UnSASPing senescence: unmasking tumor suppression?

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Item Type:	Editorial
Title:	UnSASPing senescence: unmasking tumor suppression?
Creators Name:	Schmitt, C.A.
Abstract:	Cellular senescence serves as a barrier to tumor development and a principle effector of anti-cancer therapy, but the largely pro-inflammatory senescence-associated secretory phenotype (SASP) may drive tumor promotion and contribute to age-related pathologies. In this issue of Cancer Cell, Georgilis et al. present SASP-deprived senescence as a potential therapeutic perspective.
Keywords:	Alternative Splicing, Carcinogenesis, Cellular Senescence, Heterogeneous-Nuclear Ribonucleoproteins, Neoplasms, Phenotype, Polypyrimidine Tract-Binding Protein
Source:	Cancer Cell
ISSN:	1535-6108
Publisher:	Cell Press / Elsevier
Volume:	34
Number:	1
Page Range:	6-8
Date:	9 July 2018
Official Publication:	https://doi.org/10.1016/j.ccell.2018.06.009
PubMed:	View item in PubMed

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