Organophosphorus-mediated N-N bond formation: facile access to 3-amino-2H-indazoles

Tools

Item Type:	Article
Title:	Organophosphorus-mediated N-N bond formation: facile access to 3-amino-2H-indazoles
Creators Name:	Bel Abed, H., Schoene, J., Christmann, M. and Nazare, M.
Abstract:	A convenient and efficient strategy has been devised to access 3-amino-2H-indazole derivatives in two steps from readily available starting materials. The conversion of 2-nitrobenzonitriles to substituted benzamidines followed by an organophosphorus-mediated reductive cyclization and a subsequent N-N bond formation afforded 3-amino-2H-indazoles in good to excellent yields.
Source:	Organic & Biomolecular Chemistry
ISSN:	1477-0520
Publisher:	Royal Society of Chemistry
Volume:	14
Number:	36
Page Range:	8520-8528
Date:	28 September 2016
Official Publication:	https://doi.org/10.1039/c6ob01544a
PubMed:	View item in PubMed

Repository Staff Only: item control page