Identifying RBP targets with RIP-seq

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Item Type:	Article
Title:	Identifying RBP targets with RIP-seq
Creators Name:	Wessels, H.H., Hirsekorn, A., Ohler, U. and Mukherjee, N.
Abstract:	Throughout their lifetime RNA molecules interact with a variety of RNA-binding proteins (RBPs). RBPs control gene expression by regulating splicing, polyadenylation, editing, transport, stability, and translation of RNA. There are ~1500 RBPs encoded by the human genome and recent studies have detected ~1100 proteins directly interacting with polyadenylated RNA. Identifying the RNAs bound by RBPs will continue to provide important insights into the regulation of gene expression.
Keywords:	Ribonucleoprotein, Immunoprecipitation, RNA-Binding Protein, RNA-Seq
Source:	Methods in Molecular Biology
Series Name:	Methods in Molecular Biology
Title of Book:	Post-Transcriptional Gene Regulation
ISSN:	1064-3745
ISBN:	978-1-4939-3066-1
Publisher:	Springer / Humana Press
Volume:	1358
Page Range:	141-152
Number of Pages:	353
Date:	2016
Official Publication:	https://doi.org/10.1007/978-1-4939-3067-8_9
PubMed:	View item in PubMed

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