Accurate and universal delineation of prokaryotic species

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Item Type:	Article
Title:	Accurate and universal delineation of prokaryotic species
Creators Name:	Mende, D.R., Sunagawa, S., Zeller, G. and Bork, P.
Abstract:	The exponentially increasing number of sequenced genomes necessitates fast, accurate, universally applicable and automated approaches for the delineation of prokaryotic species. We developed specI (species identification tool; http://www.bork.embl.de/software/specI/), a method to group organisms into species clusters based on 40 universal, single-copy phylogenetic marker genes. Applied to 3,496 prokaryotic genomes, specI identified 1,753 species clusters. Of 314 discrepancies with a widely used taxonomic classification, >62% were resolved by literature support.
Keywords:	16S Ribosomal RNA, Factual Databases, Genetic Markers, Genome, Phylogeny, Prochlorococcus, Prokaryotic Cells, Proteins, Sequence Alignment, Taxonomic DNA Barcoding
Source:	Nature Methods
ISSN:	1548-7091
Publisher:	Nature Publishing Group
Volume:	10
Number:	9
Page Range:	881-884
Date:	September 2013
Official Publication:	https://doi.org/10.1038/nmeth.2575
PubMed:	View item in PubMed

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