Seeing elephants and drinking water from a porcelain vase - a case of septin-7 antibody-associated encephalitis presenting as a severe disorganized psychosis

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Item Type:	Letter
Title:	Seeing elephants and drinking water from a porcelain vase - a case of septin-7 antibody-associated encephalitis presenting as a severe disorganized psychosis
Creators:	Gaebler, Arnim Johannes ORCID: https://orcid.org/0000-0002-8816-3415, Arlt, Friederike A ORCID: https://orcid.org/0000-0002-0112-8685, Scharf, Madeleine, Wolking, Stefan, Weber, Yvonne ORCID: https://orcid.org/0000-0002-0806-5592, Tauber, Simone, Kirchner, Marieluise ORCID: https://orcid.org/0000-0002-7049-534X, Mertins, Philipp ORCID: https://orcid.org/0000-0002-2245-528X, Boy, Christian, Neuner, Irene ORCID: https://orcid.org/0000-0002-5164-8873, Frodl, Thomas ORCID: https://orcid.org/0000-0002-8113-6959, Tebartz van Elst, Ludger ORCID: https://orcid.org/0000-0002-2274-5447, Prüss, Harald ORCID: https://orcid.org/0000-0002-8283-7976 and Novakovic, Ana
Abstract:	Identifying autoimmune encephalitis (AIE) in patients with predominant psychiatric symptoms poses a diagnostic challenge for psychiatrists and neurologists, especially when CSF and MRI findings are inconclusive. We report a case of septin-7 AIE presenting as steroid-responsive psychosis, whose definite diagnosis could only be made years after onset.
Source:	Translational Psychiatry
ISSN:	2158-3188
Publisher:	Nature Publishing Group
Volume:	16
Number:	1
Page Range:	71
Date:	11 February 2026
Official Publication:	https://doi.org/10.1038/s41398-026-03877-y
PubMed:	View item in PubMed

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