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| Item Type: | Editorial |
|---|---|
| Title: | Keep them close: PRC2 poises enhancer-promoter interactions at anterior neuronal genes |
| Creators Name: | Caglio, Giulia, Torlai Triglia, E. and Pombo, A. |
| Abstract: | Enhancers exist in different epigenetic states: active, primed, or poised. However, it is not yet understood how the different enhancer states influence gene activation. In this issue of Cell Stem Cell, Cruz-Molina et al. (2017) unravel how poised enhancers activate anterior neural genes and the role of Polycomb proteins in enhancer-promoter contacts. |
| Keywords: | Enhancer Elements, Genetic, Epigenesis, Genetic, Models, Theoretical, Neurons, Polycomb Repressive Complex, Promoter Regions, Genetic, Animals, Mice |
| Source: | Cell Stem Cell |
| ISSN: | 1934-5909 |
| Publisher: | Cell Press |
| Volume: | 20 |
| Number: | 5 |
| Page Range: | 573-575 |
| Date: | 4 May 2017 |
| Official Publication: | https://doi.org/10.1016/j.stem.2017.04.006 |
| PubMed: | View item in PubMed |
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