Repeat-element driven activation of proto-oncogenes in human malignancies

Item Type:	Article
Title:	Repeat-element driven activation of proto-oncogenes in human malignancies
Creators Name:	Lamprecht, B. and Bonifer, C. and Mathas, S.
Abstract:	Recent data demonstrated that the aberrant activity of endogenous repetitive elements of the DNA in humans can drive the expression of proto-oncogenes. This article summarizes these results and gives an outlook on the impact of these findings on the pathogenesis and therapy of human cancer.
Keywords:	LTR, Hodgkin Lymphoma, CSF-1 Receptor, Epigenetic Reprogramming, DNA Methylation
Source:	Cell Cycle
ISSN:	1538-4101
Publisher:	Landes Bioscience
Volume:	9
Number:	21
Page Range:	4276-4281
Date:	November 2010
Official Publication:	https://doi.org/10.4161/cc.9.21.13682
PubMed:	View item in PubMed

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