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SMART 6: recent updates and new developments

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Item Type:Article
Title:SMART 6: recent updates and new developments
Creators Name:Letunic, I. and Doerks, T. and Bork, P.
Abstract:Simple modular architecture research tool (SMART) is an online tool (http://smart.embl.de/) for the identification and annotation of protein domains. It provides a user-friendly platform for the exploration and comparative study of domain architectures in both proteins and genes. The current release of SMART contains manually curated models for 784 protein domains. Recent developments were focused on further data integration and improving user friendliness. The underlying protein database based on completely sequenced genomes was greatly expanded and now includes 630 species, compared to 191 in the previous release. As an initial step towards integrating information on biological pathways into SMART, our domain annotations were extended with data on metabolic pathways and links to several pathways resources. The interaction network view was completely redesigned and is now available for more than 2 million proteins. In addition to the standard web access to the database, users can now query SMART using distributed annotation system (DAS) or through a simple object access protocol (SOAP) based web service.
Keywords:Protein Databases, Internet, Metabolic Networks and Pathways, Protein Interaction Mapping, Tertiary Protein Structure, Software, User-Computer Interface
Source:Nucleic Acids Research
Publisher:Oxford University Press
Number:Database Issue
Page Range:D229-D232
Date:January 2009
Official Publication:https://doi.org/10.1093/nar/gkn808
PubMed:View item in PubMed

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