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Protein quality control: On IPODs and other JUNQ

Official URL:https://doi.org/10.1016/j.cub.2008.09.036
PubMed:View item in PubMed
Creators Name:Bagola, K. and Sommer, T.
Journal Title:Current Biology
Journal Abbreviation:Curr Biol
Volume:18
Number:21
Page Range:R1019-R1021
Date:11 November 2008
Keywords:Cell Compartmentation, Protein Folding, Proteins, Physiological Stress, Ubiquitination
Abstract:The accumulation of misfolded cytosolic or aggregation-prone proteins leads to cellular stress. To protect the cell, damaged or aggregated proteins are actively sequestered in two newly discovered quality control compartments, JUNQ and IPOD, which are highly conserved in evolution.
ISSN:0960-9822
Publisher:Cell Press (U.S.A.)
Item Type:Editorial

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