cag+ Helicobacter pylori induces homotypic aggregation of macrophage-like cells by up-regulation and recruitment of intracellular adhesion molecule 1 to the cell surface

Item Type:	Article
Title:	cag+ Helicobacter pylori induces homotypic aggregation of macrophage-like cells by up-regulation and recruitment of intracellular adhesion molecule 1 to the cell surface
Creators Name:	Moese, S. and Selbach, M. and Meyer, T.F. and Backert, S.
Abstract:	Infection with cag+ but not cag-negative Helicobacter pylori leads to the formation of large homotypic aggregates of macrophage-like cells. Intracellular adhesion molecule 1 is up-regulated and recruited to the cell surface of infected cells and mediates the aggregation via lymphocyte function-associated molecule 1. This signaling may regulate cell-cell interactions and inflammatory responses.
Keywords:	Bacterial Antigens, Bacterial Proteins, Cell Aggregation, Cell Membrane, Drosophila Proteins, Helicobacter pylori
Source:	Infection and Immunity
ISSN:	0019-9567
Publisher:	American Society for Microbiology
Volume:	70
Number:	8
Page Range:	4687-4691
Date:	August 2002
Official Publication:	https://doi.org/10.1128/IAI.70.8.4687-4691.2002
PubMed:	View item in PubMed

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