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Lipoproteins and their receptors in embryonic development: more than cholesterol clearance

Item Type:Review
Title:Lipoproteins and their receptors in embryonic development: more than cholesterol clearance
Creators Name:Willnow, T.E. and Hammes, A. and Eaton, S.
Abstract:Previously, the relevance of lipoproteins and their receptors has mainly been discussed in terms of cholesterol clearance in the adult organism. Now, findings from nematodes to fruit flies to mammals all point towards novel and unexpected roles for lipoprotein metabolism in the control of key regulatory pathways in the developing embryo, including signaling through steroid hormones and throughout the hedgehog and Wnt signaling pathways. Here, we discuss the emerging view of how lipoproteins and their receptors regulate embryogenesis.
Keywords:Cholesterol, Embryonic Development, Gonadal Steroid Hormones, Lipoprotein Receptors, Lipoproteins, Animals , Mice
Source:Development
ISSN:0950-1991
Publisher:Company of Biologists (U.K.)
Volume:134
Number:18
Page Range:3239-3249
Date:September 2007
Official Publication:https://doi.org/10.1242/dev.004408
PubMed:View item in PubMed

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