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Fluorinated 3'-deoxythymidine derivatives, a method for their preparation and their use

Item Type:Patent
Title:Fluorinated 3'-deoxythymidine derivatives, a method for their preparation and their use
Creators Name:Baerwolff, D. and Lindner, R. and Munz, D.L. and Michael, R.
Abstract:The invention relates to new side chain-fluorinated 3'-deoxythymidine derivatives of the general formula (I) or physiological acceptable esters thereof, wherein R = CH218F; CH18F2; CH2F or CHF2 and Y = H, N3 or Hal. The invention also relates to a simple and efficient method for the preparation of these 3'-deoxythymidines of formula (I) and to the use of the 18F-containing compounds of formula (I) or of a pharmaceutical composition comprising these compounds for the diagnosis of tumors in positron emission tomography (PET).
Date:2 November 2006

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