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New developments in the InterPro database

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Item Type:Article
Title:New developments in the InterPro database
Creators Name:Mulder, N.J. and Apweiler, R. and Attwood, T.K. and Bairoch, A. and Bateman, A. and Binns, D. and Bork, P. and Buillard, V. and Cerutti, L. and Copley, R. and Courcelle, E. and Das, U. and Daugherty, L. and Dibley, M. and Finn, R. and Fleischmann, W. and Gough, J. and Haft, D. and Hulo, N. and Hunter, S. and Kahn, D. and Kanapin, A. and Kejariwal, A. and Labarga, A. and Langendijk-Genevaux, P.S. and Lonsdale, D. and Lopez, R. and Letunic, I. and Madera, M. and Maslen, J. and McAnulla, C. and McDowall, J. and Mistry, J. and Mitchell, A. and Nikolskaya, A.N. and Orchard, S. and Orengo, C. and Petryszak, R. and Selengut, J.D. and Sigrist, C.J. and Thomas, P.D. and Valentin, F. and Wilson, D. and Wu, C.H. and Yeats, C.
Abstract:InterPro is an integrated resource for protein families, domains and functional sites, which integrates the following protein signature databases: PROSITE, PRINTS, ProDom, Pfam, SMART, TIGRFAMs, PIRSF, SUPERFAMILY, Gene3D and PANTHER. The latter two new member databases have been integrated since the last publication in this journal. There have been several new developments in InterPro, including an additional reading field, new database links, extensions to the web interface and additional match XML files. InterPro has always provided matches to UniProtKB proteins on the website and in the match XML file on the FTP site. Additional matches to proteins in UniParc (UniProt archive) are now available for download in the new match XML files only. The latest InterPro release (13.0) contains more than 13 000 entries, covering over 78% of all proteins in UniProtKB. The database is available for text- and sequence-based searches via a webserver (http://www.ebi.ac.uk/interpro), and for download by anonymous FTP (ftp://ftp.ebi.ac.uk/pub/databases/interpro). The InterProScan search tool is now also available via a web service at http://www.ebi.ac.uk/Tools/webservices/WSInterProScan.html.
Keywords:Internet, Protein Databases, Protein Sequence Analysis, Proteins, Systems Integration, Tertiary Protein Structure, User-Computer Interface
Source:Nucleic Acids Research
ISSN:0305-1048
Publisher:Oxford University Press
Volume:35
Number:Database Issue
Page Range:D224-D228
Date:January 2007
Official Publication:https://doi.org/10.1093/nar/gkl841
PubMed:View item in PubMed

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