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Comprehensive suppression of the renin-angiotensin-aldosterone system in chronic kidney disease: Covering all of the bases

Item Type:Editorial
Title:Comprehensive suppression of the renin-angiotensin-aldosterone system in chronic kidney disease: Covering all of the bases
Creators Name:Weinberger, M.H. and Luft, F.C.
Abstract:Reducing proteinuria and blood pressure in chronic kidney disease (CKD) decreases rate of progression. Inhibition of the renin-angiotensin system by angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers is beneficial in reducing proteinuria but incomplete in suppressing aldosterone production and its renal effects. Adding aldosterone receptor blockers to these other agents may further halt the progression of CKD.
Keywords:Aldosterone Antagonists, Angiotensin II Type 1 Receptor Blockers, Angiotensin-Converting Enzyme Inhibitors, Chronic Renal Insufficiency, Renin-Angiotensin System
Source:Kidney International
ISSN:0085-2538
Publisher:Nature Publishing Group (U.S.A.)
Volume:70
Number:12
Page Range:2051-2053
Date:2 December 2006
Official Publication:https://doi.org/10.1038/sj.ki.5002007
PubMed:View item in PubMed

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