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Quantification of insect genome divergence

Item Type:Article
Title:Quantification of insect genome divergence
Creators Name:Zdobnov, E.M. and Bork, P.
Abstract:The recent sequencing of twelve insect genomes has enabled us to quantify their divergence using synteny conservation and sequence identity of single-copy orthologs. Protein identity correlates well with synteny and is about three times more conserved, an observation consistent with comparisons among vertebrates. The observed distribution of the lengths of synteny blocks follows a power law and differs from the expectations of the currently accepted random breakage model. Our results show that there is only limited selection for conservation of gene order and reveal a few hundred genes, proximity among which seems to be vital.
Keywords:Genetic Models, Genetic Variation, Genome, Genomics, Insect Proteins, Phylogeny, Synteny, Animals, Insects
Source:Trends in Genetics
ISSN:0168-9525
Publisher:Elsevier (The Netherlands)
Volume:23
Number:1
Page Range:16-20
Date:January 2007
Official Publication:https://doi.org/10.1016/j.tig.2006.10.004
PubMed:View item in PubMed

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