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L(ou)sy miRNA targets?

Item Type:Editorial
Title:L(ou)sy miRNA targets?
Creators Name:Rajewsky, N.
Abstract:MicroRNAs (miRNAs) are noncoding small RNAs thought to post-transcriptionally regulate many metazoan genes by binding to partially complementary sites in target messenger RNAs. In this issue, Didiano and Hobert examine known and predicted targets of the nematode lsy-6 miRNA, question the general validity of previously proposed rules about miRNA-target interactions and suggest that many functional miRNA targets might be context dependent, as seen in metazoan gene regulation by transcription factors.
Keywords:3' Untranslated Regions, Base Pairing, Base Sequence, MicroRNAs, Molecular Sequence Data, Animals, Caenorhabditis Elegans
Source:Nature Structural & Molecular Biology
ISSN:1545-9993
Publisher:Nature Publishing Group (U.K.)
Volume:13
Number:9
Page Range:754-755
Date:September 2006
Official Publication:https://doi.org/10.1038/nsmb0906-754
PubMed:View item in PubMed

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