Linkage analysis in German breast cancer families with early onset of the disease, using highly polymorphic markers from the chromosome 17q11-q24 region

Item Type:	Article
Title:	Linkage analysis in German breast cancer families with early onset of the disease, using highly polymorphic markers from the chromosome 17q11-q24 region
Creators Name:	Zimmermann, W. and Bender, E. and Rohde, K. and Reis, A. and Wiseman, R. and Futreal, A. and Krause, H. and Prokoph, H. and Werner, S. and Scherneck, S.
Abstract:	Linkage analysis in German breast cancer families with early onset of the disease by using six markers on chromosome 17q11-q24 has been carried out. In the region between markers D17S250 and GH, three markers showed positive LOD scores at an estimated distance of zero. Evidence for linkage is greatest for D17S250, with a LOD score of 2.42.
Keywords:	Breast Neoplasms, Chromosome Mapping, Family Health, Genetic Linkage, Genetic Markers, Genetic Polymorphism, Germany, Hereditary Neoplastic Syndromes, Lod Score, Lymphocytes, Neoplasm DNA, Ovarian Neoplasms, Pair 17 Human Chromosomes, Pedigree, Proto-Oncogenes, Transformed Cell Line
Source:	American Journal of Human Genetics
ISSN:	0002-9297
Publisher:	University of Chicago Press
Volume:	52
Number:	4
Page Range:	789-791
Date:	April 1993
Official Publication:	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1682094/
PubMed:	View item in PubMed

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