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Plasma exchange for primary autoimmune autonomic failure

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Official URL:https://doi.org/10.1056/NEJMoa051719
PubMed:View item in PubMed
Creators Name:Schroeder, C. and Vernino, S. and Birkenfeld, A.L. and Tank, J. and Heusser, K. and Lipp, A. and Benter, T. and Lindschau, C. and Kettritz, R. and Luft, F.C. and Jordan, J.
Journal Title:New England Journal of Medicine
Journal Abbreviation:N Engl J Med
Volume:353
Number:15
Page Range:1585-1590
Date:13 October 2005
Keywords:Autoantibodies, Autoimmune Diseases, Autonomic Ganglia, Autonomic Nervous System Diseases, Cholinergic Receptors, Combined Modality Therapy, Glucocorticoids, Immunosuppression, Plasma Exchange, Prednisolone, Recurrence, Syncope
Abstract:We report on a patient with long-standing severe autonomic failure that affected his sympathetic and parasympathetic nervous systems. Antibodies against the ganglionic acetylcholine receptors were detected in the serum. Removal of the antibodies by means of plasma exchange resulted in a dramatic clinical improvement.
ISSN:0028-4793
Publisher:Massachusetts Medical Society (U.S.A.)
Item Type:Article

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