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Plasma exchange for primary autoimmune autonomic failure

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Item Type:Article
Title:Plasma exchange for primary autoimmune autonomic failure
Creators Name:Schroeder, C. and Vernino, S. and Birkenfeld, A.L. and Tank, J. and Heusser, K. and Lipp, A. and Benter, T. and Lindschau, C. and Kettritz, R. and Luft, F.C. and Jordan, J.
Abstract:We report on a patient with long-standing severe autonomic failure that affected his sympathetic and parasympathetic nervous systems. Antibodies against the ganglionic acetylcholine receptors were detected in the serum. Removal of the antibodies by means of plasma exchange resulted in a dramatic clinical improvement.
Keywords:Autoantibodies, Autoimmune Diseases, Autonomic Ganglia, Autonomic Nervous System Diseases, Cholinergic Receptors, Combined Modality Therapy, Glucocorticoids, Immunosuppression, Plasma Exchange, Prednisolone, Recurrence, Syncope
Source:New England Journal of Medicine
ISSN:0028-4793
Publisher:Massachusetts Medical Society (U.S.A.)
Volume:353
Number:15
Page Range:1585-1590
Date:13 October 2005
Official Publication:https://doi.org/10.1056/NEJMoa051719
PubMed:View item in PubMed

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